fulvestrant-985 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fulvestrant-985 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARFRP1 ADP-ribosylation factor related protein 1
ATN1 atrophin 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
CA11 carbonic anhydrase XI
CABIN1 calcineurin binding protein 1
CAPN9 calpain 9
CCHCR1 coiled-coil alpha-helical rod protein 1
CCNG2 cyclin G2
COL9A2 collagen, type IX, alpha 2
CTIF CBP80/20-dependent translation initiation factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFHD1 EF-hand domain family, member D1
EFNA5 ephrin-A5
EFR3B EFR3 homolog B (S. cerevisiae)
EIF5A eukaryotic translation initiation factor 5A
FAM174B family with sequence similarity 174, member B
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
FZD2 frizzled class receptor 2
GPER1 G protein-coupled estrogen receptor 1
GSTM1 glutathione S-transferase mu 1
HCAR3 hydroxycarboxylic acid receptor 3
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HNMT histamine N-methyltransferase
HNRNPL heterogeneous nuclear ribonucleoprotein L
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1R1 interleukin 1 receptor, type I
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0513 KIAA0513
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEPR leptin receptor
LINC00339 long intergenic non-protein coding RNA 339
LPIN1 lipin 1
LUZP1 leucine zipper protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LZTR1 leucine-zipper-like transcription regulator 1
MAGOH2P mago-nashi homolog 2, pseudogene
MED16 mediator complex subunit 16
MIA3 melanoma inhibitory activity family, member 3
MT1F metallothionein 1F
MTA2 metastasis associated 1 family, member 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NF2 neurofibromin 2 (merlin)
NIPAL2 NIPA-like domain containing 2
PAOX polyamine oxidase (exo-N4-amino)
PDE4DIP phosphodiesterase 4D interacting protein
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKCA protein kinase C, alpha
PRKG2 protein kinase, cGMP-dependent, type II
PRX periaxin
PTCH1 patched 1
PYY peptide YY
RAD51B RAD51 paralog B
RIN3 Ras and Rab interactor 3
RNF208 ring finger protein 208
RNF43 ring finger protein 43
RPL10 ribosomal protein L10
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A8 S100 calcium binding protein A8
SDF4 stromal cell derived factor 4
SENP5 SUMO1/sentrin specific peptidase 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFT2D2 SFT2 domain containing 2
SIX2 SIX homeobox 2
SLAMF8 SLAM family member 8
SMTN smoothelin
SRSF6 serine/arginine-rich splicing factor 6
SSX1 synovial sarcoma, X breakpoint 1
STK11 serine/threonine kinase 11
STON1 stonin 1
STXBP6 syntaxin binding protein 6 (amisyn)
SYNGR1 synaptogyrin 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TDRKH tudor and KH domain containing
TGFB1 transforming growth factor, beta 1
TNK1 tyrosine kinase, non-receptor, 1
TPI1 triosephosphate isomerase 1
TRAFD1 TRAF-type zinc finger domain containing 1
TRAPPC9 trafficking protein particle complex 9
TRIB2 tribbles pseudokinase 2
TRIM21 tripartite motif containing 21
TSPYL2 TSPY-like 2
USB1 U6 snRNA biogenesis 1
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB40 zinc finger and BTB domain containing 40
ZNF446 zinc finger protein 446
ZNF532 zinc finger protein 532
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKRD11 ankyrin repeat domain 11
ANKRD36B ankyrin repeat domain 36B
ASRGL1 asparaginase like 1
BARD1 BRCA1 associated RING domain 1
BRPF1 bromodomain and PHD finger containing, 1
C1ORF56 chromosome 1 open reading frame 56
CCDC15 coiled-coil domain containing 15
CISH cytokine inducible SH2-containing protein
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COA7 cytochrome c oxidase assembly factor 7 (putative)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPTP ceramide-1-phosphate transfer protein
CRBN cereblon
CXCL12 chemokine (C-X-C motif) ligand 12
DCAF16 DDB1 and CUL4 associated factor 16
EGR3 early growth response 3
EPHA4 EPH receptor A4
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAM46A family with sequence similarity 46, member A
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FICD FIC domain containing
FNDC3B fibronectin type III domain containing 3B
FOXC1 forkhead box C1
FOXO3 forkhead box O3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HELLS helicase, lymphoid-specific
HIST1H4C histone cluster 1, H4c
HMBOX1 homeobox containing 1
HOOK1 hook microtubule-tethering protein 1
IER3 immediate early response 3
ING3 inhibitor of growth family, member 3
IPP intracisternal A particle-promoted polypeptide
KLF7 Kruppel-like factor 7 (ubiquitous)
KRI1 KRI1 homolog (S. cerevisiae)
L2HGDH L-2-hydroxyglutarate dehydrogenase
MCM3AP-AS1 MCM3AP antisense RNA 1
MED1 mediator complex subunit 1
MEIS3P1 Meis homeobox 3 pseudogene 1
METTL8 methyltransferase like 8
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIS18BP1 MIS18 binding protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLIP myosin regulatory light chain interacting protein
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUBPL nucleotide binding protein-like
OXR1 oxidation resistance 1
PCYOX1 prenylcysteine oxidase 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PEX26 peroxisomal biogenesis factor 26
PHACTR2 phosphatase and actin regulator 2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POGLUT1 protein O-glucosyltransferase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PTCD2 pentatricopeptide repeat domain 2
PTER phosphotriesterase related
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SETD6 SET domain containing 6
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A6 solute carrier family 16, member 6
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC35E1 solute carrier family 35, member E1
SLC38A1 solute carrier family 38, member 1
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA21 small nucleolar RNA, H/ACA box 21
SPIN1 spindlin 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNJ2BP synaptojanin 2 binding protein
TM7SF3 transmembrane 7 superfamily member 3
TMEM260 transmembrane protein 260
TSKU tsukushi, small leucine rich proteoglycan
TTPAL tocopherol (alpha) transfer protein-like
UGCG UDP-glucose ceramide glucosyltransferase
UNKL unkempt family zinc finger-like
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF12 zinc finger protein 12
ZNF124 zinc finger protein 124
ZNF148 zinc finger protein 148
ZNF160 zinc finger protein 160
ZNF281 zinc finger protein 281
ZNF331 zinc finger protein 331
ZNF430 zinc finger protein 430
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF654 zinc finger protein 654
ZNF721 zinc finger protein 721
ZNF91 zinc finger protein 91