fulvestrant-6918 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


199 genes differentially expressed following the fulvestrant-6918 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ANKRD12 ankyrin repeat domain 12
ARG2 arginase 2
ASTE1 asteroid homolog 1 (Drosophila)
ATF5 activating transcription factor 5
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BICD2 bicaudal D homolog 2 (Drosophila)
C12ORF29 chromosome 12 open reading frame 29
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP290 centrosomal protein 290kDa
CLCN3 chloride channel, voltage-sensitive 3
CPE carboxypeptidase E
CPNE3 copine III
CXCL2 chemokine (C-X-C motif) ligand 2
CXORF56 chromosome X open reading frame 56
DSC2 desmocollin 2
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
E2F8 E2F transcription factor 8
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGF epidermal growth factor
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELMO2 engulfment and cell motility 2
FAM149B1 family with sequence similarity 149, member B1
FAS Fas cell surface death receptor
FGF2 fibroblast growth factor 2 (basic)
GPC4 glypican 4
HAUS6 HAUS augmin-like complex, subunit 6
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HOOK1 hook microtubule-tethering protein 1
HOXB5 homeobox B5
HSPG2 heparan sulfate proteoglycan 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPACT impact RWD domain protein
IQGAP1 IQ motif containing GTPase activating protein 1
IRF2 interferon regulatory factor 2
KIAA0100 KIAA0100
KIAA0485 uncharacterized LOC57235
KLHL24 kelch-like family member 24
KRAS Kirsten rat sarcoma viral oncogene homolog
LRP12 low density lipoprotein receptor-related protein 12
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MDM1 Mdm1 nuclear protein homolog (mouse)
MED13L mediator complex subunit 13-like
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NBN nibrin
NME5 NME/NM23 family member 5
NMT2 N-myristoyltransferase 2
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
ORAI3 ORAI calcium release-activated calcium modulator 3
OSBPL3 oxysterol binding protein-like 3
OXR1 oxidation resistance 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCLO piccolo presynaptic cytomatrix protein
PGK1 phosphoglycerate kinase 1
PHF3 PHD finger protein 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNISR PNN-interacting serine/arginine-rich protein
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRMT2 protein arginine methyltransferase 2
PRRC2C proline-rich coiled-coil 2C
PSME4 proteasome (prosome, macropain) activator subunit 4
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RAD23B RAD23 homolog B (S. cerevisiae)
RBL2 retinoblastoma-like 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL14 ribosomal protein L14
RPL38 ribosomal protein L38
SEC14L1 SEC14-like 1 (S. cerevisiae)
SETDB1 SET domain, bifurcated 1
SF1 splicing factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SUGP1 SURP and G patch domain containing 1
TBC1D30 TBC1 domain family, member 30
TBL1X transducin (beta)-like 1X-linked
TCAF1 TRPM8 channel-associated factor 1
TGFBR3 transforming growth factor, beta receptor III
TGIF2 TGFB-induced factor homeobox 2
TGOLN2 trans-golgi network protein 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPP2 tripeptidyl peptidase II
TPR translocated promoter region, nuclear basket protein
TWF1 twinfilin actin binding protein 1
UBOX5 U-box domain containing 5
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USF2 upstream transcription factor 2, c-fos interacting
USP6 ubiquitin specific peptidase 6
WWC2 WW and C2 domain containing 2
ZBTB38 zinc finger and BTB domain containing 38
ZCCHC10 zinc finger, CCHC domain containing 10
ZFX zinc finger protein, X-linked
ZNF107 zinc finger protein 107
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALG3 ALG3, alpha-1,3- mannosyltransferase
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARL2 ADP-ribosylation factor-like 2
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BSG basigin (Ok blood group)
C11ORF80 chromosome 11 open reading frame 80
CAPNS1 calpain, small subunit 1
CDA cytidine deaminase
CDC37 cell division cycle 37
CEP85 centrosomal protein 85kDa
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CRIP2 cysteine-rich protein 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYB5R1 cytochrome b5 reductase 1
CYB5R2 cytochrome b5 reductase 2
DCLRE1A DNA cross-link repair 1A
DDA1 DET1 and DDB1 associated 1
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND5B DENN/MADD domain containing 5B
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
EDC3 enhancer of mRNA decapping 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP3 elongator acetyltransferase complex subunit 3
EML4 echinoderm microtubule associated protein like 4
EMP3 epithelial membrane protein 3
ERI3 ERI1 exoribonuclease family member 3
FAM86C1 family with sequence similarity 86, member C1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLTP glycolipid transfer protein
GMIP GEM interacting protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRPR gastrin-releasing peptide receptor
GSTM2 glutathione S-transferase mu 2 (muscle)
GYS1 glycogen synthase 1 (muscle)
HYAL3 hyaluronoglucosaminidase 3
IFI30 interferon, gamma-inducible protein 30
IFI6 interferon, alpha-inducible protein 6
JUNB jun B proto-oncogene
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOXL1 lysyl oxidase-like 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MLF2 myeloid leukemia factor 2
MOSPD3 motile sperm domain containing 3
MPDU1 mannose-P-dolichol utilization defect 1
MTA2 metastasis associated 1 family, member 2
NUTF2 nuclear transport factor 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDH12 protocadherin 12
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PECR peroxisomal trans-2-enoyl-CoA reductase
PGD phosphogluconate dehydrogenase
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POGK pogo transposable element with KRAB domain
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRMT5 protein arginine methyltransferase 5
PRPF8 pre-mRNA processing factor 8
PSAT1 phosphoserine aminotransferase 1
PSENEN presenilin enhancer gamma secretase subunit
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPP25 ribonuclease P/MRP 25kDa subunit
RRAS related RAS viral (r-ras) oncogene homolog
SAMD9 sterile alpha motif domain containing 9
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SHARPIN SHANK-associated RH domain interactor
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC41A3 solute carrier family 41, member 3
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SYTL2 synaptotagmin-like 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN2 tectonic family member 2
TECR trans-2,3-enoyl-CoA reductase
TM7SF2 transmembrane 7 superfamily member 2
TMEM212 transmembrane protein 212
TMEM230 transmembrane protein 230
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOR4A torsin family 4, member A
TRABD TraB domain containing
TRAPPC2L trafficking protein particle complex 2-like
TSKU tsukushi, small leucine rich proteoglycan
TSPAN1 tetraspanin 1
TTLL7 tubulin tyrosine ligase-like family member 7
UBE2M ubiquitin-conjugating enzyme E2M
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YIPF5 Yip1 domain family, member 5