fulvestrant-6867 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fulvestrant-6867 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANXA10 annexin A10
ARHGAP35 Rho GTPase activating protein 35
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCL2L1 BCL2-like 1
BCOR BCL6 corepressor
BTBD7 BTB (POZ) domain containing 7
C11ORF63 chromosome 11 open reading frame 63
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CACYBP calcyclin binding protein
CD40 CD40 molecule, TNF receptor superfamily member 5
CDK3 cyclin-dependent kinase 3
CHI3L2 chitinase 3-like 2
CLDN17 claudin 17
COL6A1 collagen, type VI, alpha 1
CORO2A coronin, actin binding protein, 2A
CORT cortistatin
CUL4B cullin 4B
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DLX2 distal-less homeobox 2
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
ELK1 ELK1, member of ETS oncogene family
EXT1 exostosin glycosyltransferase 1
FAM53B family with sequence similarity 53, member B
FLJ21369 uncharacterized protein FLJ21369
FSD1 fibronectin type III and SPRY domain containing 1
FZD7 frizzled class receptor 7
GBX2 gastrulation brain homeobox 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR107 G protein-coupled receptor 107
HDAC5 histone deacetylase 5
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IDI2-AS1 IDI2 antisense RNA 1
IGF1R insulin-like growth factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15RA interleukin 15 receptor, alpha
IL17RC interleukin 17 receptor C
IRF5 interferon regulatory factor 5
KIAA0368 KIAA0368
KLF4 Kruppel-like factor 4 (gut)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMF1 lipase maturation factor 1
LRP6 low density lipoprotein receptor-related protein 6
MAGEA12 melanoma antigen family A12
MAPK7 mitogen-activated protein kinase 7
MCM4 minichromosome maintenance complex component 4
MDM1 Mdm1 nuclear protein homolog (mouse)
MFGE8 milk fat globule-EGF factor 8 protein
MOB3B MOB kinase activator 3B
MVK mevalonate kinase
N4BP1 NEDD4 binding protein 1
NDP Norrie disease (pseudoglioma)
NFYA nuclear transcription factor Y, alpha
NFYC nuclear transcription factor Y, gamma
NIPAL2 NIPA-like domain containing 2
NPR3 natriuretic peptide receptor 3
NTSR1 neurotensin receptor 1 (high affinity)
OCRL oculocerebrorenal syndrome of Lowe
PEX3 peroxisomal biogenesis factor 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK3 polo-like kinase 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POLL polymerase (DNA directed), lambda
PTK2B protein tyrosine kinase 2 beta
PVR poliovirus receptor
RARG retinoic acid receptor, gamma
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF39 ring finger protein 39
RRP1B ribosomal RNA processing 1B
SAYSD1 SAYSVFN motif domain containing 1
SBF1 SET binding factor 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STX7 syntaxin 7
SUMO1 small ubiquitin-like modifier 1
SUN1 Sad1 and UNC84 domain containing 1
TDRD3 tudor domain containing 3
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM209 transmembrane protein 209
TUSC3 tumor suppressor candidate 3
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
WDR1 WD repeat domain 1
ZFHX2 zinc finger homeobox 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACOT8 acyl-CoA thioesterase 8
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARPIN actin-related protein 2/3 complex inhibitor
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BFSP1 beaded filament structural protein 1, filensin
BTBD18 BTB (POZ) domain containing 18
C1ORF95 chromosome 1 open reading frame 95
C1QTNF3 C1q and tumor necrosis factor related protein 3
C8B complement component 8, beta polypeptide
C8ORF44 chromosome 8 open reading frame 44
CCDC40 coiled-coil domain containing 40
CCL22 chemokine (C-C motif) ligand 22
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD300C CD300c molecule
CDK20 cyclin-dependent kinase 20
CLDN1 claudin 1
CLDN11 claudin 11
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNPY4 canopy FGF signaling regulator 4
CNTFR ciliary neurotrophic factor receptor
CNTNAP3B contactin associated protein-like 3B
CPA4 carboxypeptidase A4
CTF1 cardiotrophin 1
CTRC chymotrypsin C (caldecrin)
CTSK cathepsin K
CXORF21 chromosome X open reading frame 21
EGFL7 EGF-like-domain, multiple 7
FABP6 fatty acid binding protein 6, ileal
FAM120C family with sequence similarity 120C
FAM186A family with sequence similarity 186, member A
FBXO22 F-box protein 22
FGL1 fibrinogen-like 1
FOXC1 forkhead box C1
GALK1 galactokinase 1
GPR1 G protein-coupled receptor 1
GPR39 G protein-coupled receptor 39
GUCA1B guanylate cyclase activator 1B (retina)
HLA-DMA major histocompatibility complex, class II, DM alpha
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IL22 interleukin 22
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM4D lysine (K)-specific demethylase 4D
KIAA1324 KIAA1324
KIF13A kinesin family member 13A
KLK1 kallikrein 1
LIPG lipase, endothelial
LPPR1 lipid phosphate phosphatase-related protein type 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIP major intrinsic protein of lens fiber
NEK11 NIMA-related kinase 11
NOD1 nucleotide-binding oligomerization domain containing 1
OSMR oncostatin M receptor
PAQR5 progestin and adipoQ receptor family member V
PARP3 poly (ADP-ribose) polymerase family, member 3
PARP6 poly (ADP-ribose) polymerase family, member 6
PHOX2B paired-like homeobox 2b
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLXNA3 plexin A3
PNPLA3 patatin-like phospholipase domain containing 3
POMT2 protein-O-mannosyltransferase 2
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RHBDD3 rhomboid domain containing 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF208 ring finger protein 208
RORC RAR-related orphan receptor C
SELPLG selectin P ligand
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BGR SH3 domain binding glutamate-rich protein
SIRT6 sirtuin 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
TM4SF5 transmembrane 4 L six family member 5
TMEM212 transmembrane protein 212
TMPRSS6 transmembrane protease, serine 6
UGT8 UDP glycosyltransferase 8
UNC93B1 unc-93 homolog B1 (C. elegans)
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF212 zinc finger protein 212
ZNF219 zinc finger protein 219
ZNF667 zinc finger protein 667
ZNF671 zinc finger protein 671
ZNF747 zinc finger protein 747