folic acid-7201 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the folic acid-7201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNO cyclin O
CDKL3 cyclin-dependent kinase-like 3
COPA coatomer protein complex, subunit alpha
COPS8 COP9 signalosome subunit 8
CPN2 carboxypeptidase N, polypeptide 2
CREBZF CREB/ATF bZIP transcription factor
CRYGC crystallin, gamma C
CSE1L CSE1 chromosome segregation 1-like (yeast)
CUL4B cullin 4B
DCTN1 dynactin 1
DSC2 desmocollin 2
DXO decapping exoribonuclease
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
HRK harakiri, BCL2 interacting protein
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF3 Kruppel-like factor 3 (basic)
KRT15 keratin 15, type I
LPP LIM domain containing preferred translocation partner in lipoma
LYPD1 LY6/PLAUR domain containing 1
MANEA mannosidase, endo-alpha
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MAX MYC associated factor X
MBD3 methyl-CpG binding domain protein 3
MIIP migration and invasion inhibitory protein
MVK mevalonate kinase
MXD4 MAX dimerization protein 4
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NMT2 N-myristoyltransferase 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARVA parvin, alpha
PDLIM7 PDZ and LIM domain 7 (enigma)
PIBF1 progesterone immunomodulatory binding factor 1
QKI QKI, KH domain containing, RNA binding
RAB28 RAB28, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM12B RNA binding motif protein 12B
RER1 retention in endoplasmic reticulum sorting receptor 1
RGS14 regulator of G-protein signaling 14
RGS2 regulator of G-protein signaling 2
RNF39 ring finger protein 39
RNF6 ring finger protein (C3H2C3 type) 6
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
S100A11 S100 calcium binding protein A11
SIK2 salt-inducible kinase 2
SIX3 SIX homeobox 3
SKAP1 src kinase associated phosphoprotein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG7 SMG7 nonsense mediated mRNA decay factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD2 superoxide dismutase 2, mitochondrial
SP100 SP100 nuclear antigen
STAT1 signal transducer and activator of transcription 1, 91kDa
STK4 serine/threonine kinase 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TJAP1 tight junction associated protein 1 (peripheral)
TMEM254 transmembrane protein 254
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
VIPR2 vasoactive intestinal peptide receptor 2
WDTC1 WD and tetratricopeptide repeats 1
WWOX WW domain containing oxidoreductase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP30 ZFP30 zinc finger protein
ZFPL1 zinc finger protein-like 1
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ALPK1 alpha-kinase 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
C4ORF29 chromosome 4 open reading frame 29
CAPN15 calpain 15
CASZ1 castor zinc finger 1
CCDC9 coiled-coil domain containing 9
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGREF1 cell growth regulator with EF-hand domain 1
CIC capicua transcriptional repressor
CLASRP CLK4-associating serine/arginine rich protein
CRLF1 cytokine receptor-like factor 1
DEPTOR DEP domain containing MTOR-interacting protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EIF5A2 eukaryotic translation initiation factor 5A2
EXTL2 exostosin-like glycosyltransferase 2
FAM188A family with sequence similarity 188, member A
FBXO31 F-box protein 31
GAA glucosidase, alpha; acid
GALT galactose-1-phosphate uridylyltransferase
GAN gigaxonin
GCC1 GRIP and coiled-coil domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HCFC2 host cell factor C2
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HMHA1 histocompatibility (minor) HA-1
IDI2-AS1 IDI2 antisense RNA 1
IL15RA interleukin 15 receptor, alpha
IRF1 interferon regulatory factor 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KAT2A K(lysine) acetyltransferase 2A
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0319L KIAA0319-like
KLF11 Kruppel-like factor 11
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1S microtubule-associated protein 1S
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
PCDHB3 protocadherin beta 3
PHACTR4 phosphatase and actin regulator 4
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PODXL podocalyxin-like
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRR14L proline rich 14-like
PRSS22 protease, serine, 22
RABL6 RAB, member RAS oncogene family-like 6
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SASH1 SAM and SH3 domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A9 solute carrier family 12, member 9
SOX12 SRY (sex determining region Y)-box 12
SREK1IP1 SREK1-interacting protein 1
TBX19 T-box 19
TMEM104 transmembrane protein 104
TMEM127 transmembrane protein 127
TMEM180 transmembrane protein 180
TMEM51 transmembrane protein 51
TP53BP1 tumor protein p53 binding protein 1
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
TRIM25 tripartite motif containing 25
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC23 tetratricopeptide repeat domain 23
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
VPS9D1 VPS9 domain containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF205 zinc finger protein 205
ZNF35 zinc finger protein 35
ZNF652 zinc finger protein 652