folic acid-1790 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the folic acid-1790 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARMC4 armadillo repeat containing 4
ARR3 arrestin 3, retinal (X-arrestin)
ASB13 ankyrin repeat and SOCS box containing 13
ATG2A autophagy related 2A
BMP8A bone morphogenetic protein 8a
C9ORF156 chromosome 9 open reading frame 156
CARD9 caspase recruitment domain family, member 9
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBX6 chromobox homolog 6
CCDC177 coiled-coil domain containing 177
CCDC94 coiled-coil domain containing 94
CDHR2 cadherin-related family member 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHKA choline kinase alpha
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CRYL1 crystallin, lambda 1
CYHR1 cysteine/histidine-rich 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGR1 early growth response 1
EHD1 EH-domain containing 1
EIF4B eukaryotic translation initiation factor 4B
ELMO2 engulfment and cell motility 2
ERCC8 excision repair cross-complementation group 8
FAM189A2 family with sequence similarity 189, member A2
FAM208A family with sequence similarity 208, member A
FBXO9 F-box protein 9
FMO2 flavin containing monooxygenase 2 (non-functional)
FRS3 fibroblast growth factor receptor substrate 3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAP43 growth associated protein 43
GBAP1 glucosidase, beta, acid pseudogene 1
GDF5 growth differentiation factor 5
GIMAP5 GTPase, IMAP family member 5
GJA9 gap junction protein, alpha 9, 59kDa
GPR107 G protein-coupled receptor 107
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HNF1B HNF1 homeobox B
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB11 heat shock protein family B (small), member 11
ISCA1 iron-sulfur cluster assembly 1
KDM4B lysine (K)-specific demethylase 4B
KNOP1 lysine-rich nucleolar protein 1
LENEP lens epithelial protein
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MET MET proto-oncogene, receptor tyrosine kinase
MPHOSPH9 M-phase phosphoprotein 9
MYO1E myosin IE
NFYA nuclear transcription factor Y, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NPFFR1 neuropeptide FF receptor 1
NTNG1 netrin G1
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PCNX pecanex homolog (Drosophila)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POMT1 protein-O-mannosyltransferase 1
PRDM4 PR domain containing 4
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PXN paxillin
RAB11B RAB11B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RRBP1 ribosome binding protein 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC45A2 solute carrier family 45, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMAD3 SMAD family member 3
SNHG3 small nucleolar RNA host gene 3
STK17A serine/threonine kinase 17a
STRN striatin, calmodulin binding protein
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF3 transcription factor 3
THBS3 thrombospondin 3
TOP3A topoisomerase (DNA) III alpha
TRBC1 T cell receptor beta constant 1
TREX1 three prime repair exonuclease 1
TRIM10 tripartite motif containing 10
TRIM9 tripartite motif containing 9
TSC22D3 TSC22 domain family, member 3
TTC28 tetratricopeptide repeat domain 28
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
URM1 ubiquitin related modifier 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR2 vasoactive intestinal peptide receptor 2
WSB1 WD repeat and SOCS box containing 1
ZNF408 zinc finger protein 408
ZNF419 zinc finger protein 419
ZNF518A zinc finger protein 518A
ZNF671 zinc finger protein 671
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ADAM23 ADAM metallopeptidase domain 23
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AZI2 5-azacytidine induced 2
BCL2L2 BCL2-like 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BRD1 bromodomain containing 1
C14ORF159 chromosome 14 open reading frame 159
CCDC130 coiled-coil domain containing 130
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD101 CD101 molecule
CDC42SE1 CDC42 small effector 1
CDCA3 cell division cycle associated 3
CHMP7 charged multivesicular body protein 7
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CISH cytokine inducible SH2-containing protein
CLASRP CLK4-associating serine/arginine rich protein
CLP1 cleavage and polyadenylation factor I subunit 1
CSK c-src tyrosine kinase
CYB5R1 cytochrome b5 reductase 1
DAO D-amino-acid oxidase
DDA1 DET1 and DDB1 associated 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DERL2 derlin 2
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DPH2 DPH2 homolog (S. cerevisiae)
DSN1 DSN1, MIS12 kinetochore complex component
EIF3I eukaryotic translation initiation factor 3, subunit I
FAM117A family with sequence similarity 117, member A
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GTF2I general transcription factor IIi
H2BFS H2B histone family, member S (pseudogene)
HIST1H4C histone cluster 1, H4c
HYOU1 hypoxia up-regulated 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KATNBL1 katanin p80 subunit B-like 1
KIAA0196 KIAA0196
KIF13B kinesin family member 13B
KIF18A kinesin family member 18A
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
MED17 mediator complex subunit 17
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOSPD3 motile sperm domain containing 3
MPDU1 mannose-P-dolichol utilization defect 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MRGBP MRG/MORF4L binding protein
MRPL19 mitochondrial ribosomal protein L19
MXRA8 matrix-remodelling associated 8
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NCOA4 nuclear receptor coactivator 4
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRBP1 nuclear receptor binding protein 1
NUCB2 nucleobindin 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PEPD peptidase D
PGS1 phosphatidylglycerophosphate synthase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTER phosphotriesterase related
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RBBP5 retinoblastoma binding protein 5
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF146 ring finger protein 146
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SRBD1 S1 RNA binding domain 1
SRRD SRR1 domain containing
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD8 StAR-related lipid transfer (START) domain containing 8
STK39 serine threonine kinase 39
SYNGR2 synaptogyrin 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCC tubulin folding cofactor C
TCTN1 tectonic family member 1
TMEM106B transmembrane protein 106B
TMPRSS6 transmembrane protease, serine 6
TPD52L2 tumor protein D52-like 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSPYL2 TSPY-like 2
TTBK2 tau tubulin kinase 2
USP11 ubiquitin specific peptidase 11
WDR13 WD repeat domain 13
WDR7 WD repeat domain 7
XBP1 X-box binding protein 1
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF268 zinc finger protein 268
ZNF85 zinc finger protein 85
ZWINT ZW10 interacting kinetochore protein