fluvoxamine-7333 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the fluvoxamine-7333 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ADGRG1 adhesion G protein-coupled receptor G1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHSP alpha hemoglobin stabilizing protein
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
AUTS2 autism susceptibility candidate 2
C19ORF73 chromosome 19 open reading frame 73
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCOCO1 calcium binding and coiled-coil domain 1
CALCR calcitonin receptor
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCNG2 cyclin G2
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CFLAR CASP8 and FADD-like apoptosis regulator
CHKA choline kinase alpha
CLCN6 chloride channel, voltage-sensitive 6
CNOT4 CCR4-NOT transcription complex, subunit 4
COL5A1 collagen, type V, alpha 1
COX4I1 cytochrome c oxidase subunit IV isoform 1
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST6 cystatin E/M
CYHR1 cysteine/histidine-rich 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLX2 distal-less homeobox 2
DMPK dystrophia myotonica-protein kinase
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ERCC2 excision repair cross-complementation group 2
EXO5 exonuclease 5
FADS3 fatty acid desaturase 3
FAM212B family with sequence similarity 212, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
GCC1 GRIP and coiled-coil domain containing 1
GMEB1 glucocorticoid modulatory element binding protein 1
GREB1L growth regulation by estrogen in breast cancer-like
GTDC1 glycosyltransferase-like domain containing 1
HFE hemochromatosis
HLA-G major histocompatibility complex, class I, G
HSF1 heat shock transcription factor 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
INO80D INO80 complex subunit D
INTS3 integrator complex subunit 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
KRT13 keratin 13, type I
LAMP1 lysosomal-associated membrane protein 1
LPAR4 lysophosphatidic acid receptor 4
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MINK1 misshapen-like kinase 1
NF1 neurofibromin 1
NPTX1 neuronal pentraxin I
OPTN optineurin
PCGF3 polycomb group ring finger 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAC1 placenta-specific 1
PLSCR1 phospholipid scramblase 1
PLXNA3 plexin A3
PMP22 peripheral myelin protein 22
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAD23B RAD23 homolog B (S. cerevisiae)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REL v-rel avian reticuloendotheliosis viral oncogene homolog
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS14 ribosomal protein S14
RTN2 reticulon 2
SAP30 Sin3A-associated protein, 30kDa
SBF1 SET binding factor 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGMAR1 sigma non-opioid intracellular receptor 1
SIPA1 signal-induced proliferation-associated 1
SKIL SKI-like proto-oncogene
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SUGP1 SURP and G patch domain containing 1
THAP3 THAP domain containing, apoptosis associated protein 3
THBD thrombomodulin
TM6SF1 transmembrane 6 superfamily member 1
TMEM242 transmembrane protein 242
TMPRSS2 transmembrane protease, serine 2
TREX1 three prime repair exonuclease 1
TTC28 tetratricopeptide repeat domain 28
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WAS Wiskott-Aldrich syndrome
XK X-linked Kx blood group
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF136 zinc finger protein 136
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF516 zinc finger protein 516
ZNF614 zinc finger protein 614
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ADAP2 ArfGAP with dual PH domains 2
ADCY7 adenylate cyclase 7
AHDC1 AT hook, DNA binding motif, containing 1
ANXA2P3 annexin A2 pseudogene 3
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
CBX7 chromobox homolog 7
CCDC15 coiled-coil domain containing 15
CDC37 cell division cycle 37
CEP97 centrosomal protein 97kDa
CFL1 cofilin 1 (non-muscle)
CLCN2 chloride channel, voltage-sensitive 2
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPTP ceramide-1-phosphate transfer protein
CTC1 CTS telomere maintenance complex component 1
CYB5R1 cytochrome b5 reductase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNALI1 dynein, axonemal, light intermediate chain 1
DPF2 D4, zinc and double PHD fingers family 2
DYSF dysferlin
EFNA3 ephrin-A3
ESRP2 epithelial splicing regulatory protein 2
FLT4 fms-related tyrosine kinase 4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
GPR19 G protein-coupled receptor 19
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2BC histone cluster 1, H2bc
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HOXA5 homeobox A5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IER2 immediate early response 2
IFITM1 interferon induced transmembrane protein 1
IGFBP6 insulin-like growth factor binding protein 6
INF2 inverted formin, FH2 and WH2 domain containing
IRX4 iroquois homeobox 4
ISG15 ISG15 ubiquitin-like modifier
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
LAGE3 L antigen family, member 3
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MATK megakaryocyte-associated tyrosine kinase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NIPAL2 NIPA-like domain containing 2
NPY5R neuropeptide Y receptor Y5
ONECUT2 one cut homeobox 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PP14571 uncharacterized LOC100130449
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARS arginyl-tRNA synthetase
RFTN1 raftlin, lipid raft linker 1
RHOC ras homolog family member C
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF121 ring finger protein 121
SH3BGR SH3 domain binding glutamate-rich protein
SLC16A6 solute carrier family 16, member 6
SOX12 SRY (sex determining region Y)-box 12
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
TDRD1 tudor domain containing 1
TEFM transcription elongation factor, mitochondrial
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TSPAN5 tetraspanin 5
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP27X ubiquitin specific peptidase 27, X-linked
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZMAT5 zinc finger, matrin-type 5
ZNF219 zinc finger protein 219
ZNF428 zinc finger protein 428
ZNF557 zinc finger protein 557
ZNF665 zinc finger protein 665
ZNF862 zinc finger protein 862