flutamide-2358 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the flutamide-2358 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABI2 abl-interactor 2
ADORA1 adenosine A1 receptor
AIRE autoimmune regulator
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP7 aquaporin 7
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL4C ADP-ribosylation factor-like 4C
ARRB1 arrestin, beta 1
ATP10B ATPase, class V, type 10B
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C1ORF61 chromosome 1 open reading frame 61
C5ORF45 chromosome 5 open reading frame 45
CADM3 cell adhesion molecule 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL4A1 collagen, type IV, alpha 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSRP2 cysteine and glycine-rich protein 2
DCLK2 doublecortin-like kinase 2
DCT dopachrome tautomerase
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DMC1 DNA meiotic recombinase 1
DOCK9 dedicator of cytokinesis 9
DUSP8 dual specificity phosphatase 8
E2F4 E2F transcription factor 4, p107/p130-binding
EGR1 early growth response 1
EPHA1 EPH receptor A1
EPHB6 EPH receptor B6
EXOC7 exocyst complex component 7
FBLN1 fibulin 1
FGL1 fibrinogen-like 1
FTH1 ferritin, heavy polypeptide 1
FUS FUS RNA binding protein
GATA3 GATA binding protein 3
GPR1 G protein-coupled receptor 1
GPX2 glutathione peroxidase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFNA17 interferon, alpha 17
IGLJ3 immunoglobulin lambda joining 3
INPP1 inositol polyphosphate-1-phosphatase
IRF2BP1 interferon regulatory factor 2 binding protein 1
IVD isovaleryl-CoA dehydrogenase
JAK3 Janus kinase 3
KIF1A kinesin family member 1A
LARP4B La ribonucleoprotein domain family, member 4B
LIMD2 LIM domain containing 2
LOC284244 uncharacterized LOC284244
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAN1B1 mannosidase, alpha, class 1B, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK4 MAP/microtubule affinity-regulating kinase 4
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOBP myelin-associated oligodendrocyte basic protein
MYLK myosin light chain kinase
MYO1C myosin IC
NEB nebulin
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L3 nuclear factor, erythroid 2-like 3
NRP1 neuropilin 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PBX2 pre-B-cell leukemia homeobox 2
PEG3 paternally expressed 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLK3 polo-like kinase 3
PPARD peroxisome proliferator-activated receptor delta
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PROL1 proline rich, lacrimal 1
PTAFR platelet-activating factor receptor
RARA retinoic acid receptor, alpha
RFPL3 ret finger protein-like 3
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIN3 Ras and Rab interactor 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUFY3 RUN and FYVE domain containing 3
SCN2B sodium channel, voltage gated, type II beta subunit
SH2B1 SH2B adaptor protein 1
SIDT2 SID1 transmembrane family, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SSH3 slingshot protein phosphatase 3
SSX3 synovial sarcoma, X breakpoint 3
STC2 stanniocalcin 2
SYNJ2 synaptojanin 2
TBC1D30 TBC1 domain family, member 30
TEX261 testis expressed 261
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLE3 transducin-like enhancer of split 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM23 tripartite motif containing 23
TSPYL2 TSPY-like 2
ZNF589 zinc finger protein 589
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AEN apoptosis enhancing nuclease
AGO4 argonaute RISC catalytic component 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHCTF1 AT hook containing transcription factor 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOL6 apolipoprotein L, 6
ARMC7 armadillo repeat containing 7
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATG2B autophagy related 2B
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BMP15 bone morphogenetic protein 15
BTN3A3 butyrophilin, subfamily 3, member A3
C3 complement component 3
C6ORF47 chromosome 6 open reading frame 47
CAPN5 calpain 5
CCDC6 coiled-coil domain containing 6
CCR2 chemokine (C-C motif) receptor 2
CD244 CD244 molecule, natural killer cell receptor 2B4
CDK3 cyclin-dependent kinase 3
CEP70 centrosomal protein 70kDa
CHMP1A charged multivesicular body protein 1A
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COG4 component of oligomeric golgi complex 4
CYSLTR1 cysteinyl leukotriene receptor 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DEPDC1 DEP domain containing 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPY19L2P2 DPY19L2 pseudogene 2
DYM dymeclin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FADS2 fatty acid desaturase 2
FCHSD2 FCH and double SH3 domains 2
HIST2H2BE histone cluster 2, H2be
HS1BP3 HCLS1 binding protein 3
ICK intestinal cell (MAK-like) kinase
IFT46 intraflagellar transport 46
IFT81 intraflagellar transport 81
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
LXN latexin
MANSC1 MANSC domain containing 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK3 mitogen-activated protein kinase 3
METTL16 methyltransferase like 16
METTL2B methyltransferase like 2B
MILR1 mast cell immunoglobulin-like receptor 1
MITF microphthalmia-associated transcription factor
MLPH melanophilin
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NARFL nuclear prelamin A recognition factor-like
NPFFR1 neuropeptide FF receptor 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ORAI3 ORAI calcium release-activated calcium modulator 3
OSBPL11 oxysterol binding protein-like 11
OTUD3 OTU deubiquitinase 3
PAQR4 progestin and adipoQ receptor family member IV
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PIR pirin (iron-binding nuclear protein)
PITRM1 pitrilysin metallopeptidase 1
PMCH pro-melanin-concentrating hormone
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5B RAB5B, member RAS oncogene family
RBM4B RNA binding motif protein 4B
RFXAP regulatory factor X-associated protein
RIN1 Ras and Rab interactor 1
SAMD9 sterile alpha motif domain containing 9
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SNX15 sorting nexin 15
SYNJ2BP synaptojanin 2 binding protein
TBCCD1 TBCC domain containing 1
TBX19 T-box 19
TESK1 testis-specific kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM134 transmembrane protein 134
TMEM254 transmembrane protein 254
TMEM39B transmembrane protein 39B
TMEM57 transmembrane protein 57
TNRC6B trinucleotide repeat containing 6B
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
TRIM26 tripartite motif containing 26
TSPAN32 tetraspanin 32
TTPAL tocopherol (alpha) transfer protein-like
TXNDC15 thioredoxin domain containing 15
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WT1-AS WT1 antisense RNA
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT5 zinc finger, matrin-type 5
ZNF552 zinc finger protein 552
ZNF668 zinc finger protein 668
ZSCAN31 zinc finger and SCAN domain containing 31