fluphenazine-2697 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fluphenazine-2697 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP5 A kinase (PRKA) anchor protein 5
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALLC allantoicase
ANK2 ankyrin 2, neuronal
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANTXR1 anthrax toxin receptor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARC activity-regulated cytoskeleton-associated protein
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B9D2 B9 protein domain 2
BAIAP2 BAI1-associated protein 2
BMP8B bone morphogenetic protein 8b
C11ORF63 chromosome 11 open reading frame 63
C6ORF10 chromosome 6 open reading frame 10
CABP1 calcium binding protein 1
CALD1 caldesmon 1
CCDC40 coiled-coil domain containing 40
CD226 CD226 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CHGA chromogranin A
CLCA2 chloride channel accessory 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL1A1 collagen, type I, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CTRC chymotrypsin C (caldecrin)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DRD2 dopamine receptor D2
EMID1 EMI domain containing 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FCMR Fc fragment of IgM receptor
FDXR ferredoxin reductase
FLJ11292
FOXG1 forkhead box G1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAP43 growth associated protein 43
GAST gastrin
GRK4 G protein-coupled receptor kinase 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDAC7 histone deacetylase 7
HOXD13 homeobox D13
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI6 interferon, alpha-inducible protein 6
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL24 interleukin 24
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KIAA1045 KIAA1045
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LOC57399 uncharacterized gastric protein ZA52P
MTAP methylthioadenosine phosphorylase
MTUS1 microtubule associated tumor suppressor 1
MYBPC2 myosin binding protein C, fast type
NCKAP1 NCK-associated protein 1
NOV nephroblastoma overexpressed
NRG2 neuregulin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PHTF2 putative homeodomain transcription factor 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRPH peripherin
PTGDR prostaglandin D2 receptor (DP)
QSER1 glutamine and serine rich 1
RFC1 replication factor C (activator 1) 1, 145kDa
RGS14 regulator of G-protein signaling 14
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD3 SMAD family member 3
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOX5 SRY (sex determining region Y)-box 5
SPARCL1 SPARC-like 1 (hevin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TBR1 T-box, brain, 1
TCAF1 TRPM8 channel-associated factor 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TESK1 testis-specific kinase 1
TGFBR3 transforming growth factor, beta receptor III
TMEM140 transmembrane protein 140
TMPRSS4 transmembrane protease, serine 4
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
ZNF500 zinc finger protein 500
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD55 ankyrin repeat domain 55
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
BDKRB1 bradykinin receptor B1
BTBD18 BTB (POZ) domain containing 18
CD1D CD1d molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIDEC cell death-inducing DFFA-like effector c
CLIP2 CAP-GLY domain containing linker protein 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYGC crystallin, gamma C
CSF3R colony stimulating factor 3 receptor (granulocyte)
DOC2A double C2-like domains, alpha
DOLK dolichol kinase
DPEP2 dipeptidase 2
DSCAM Down syndrome cell adhesion molecule
DTX2 deltex 2, E3 ubiquitin ligase
FAM114A2 family with sequence similarity 114, member A2
FAM127B family with sequence similarity 127, member B
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGF6 fibroblast growth factor 6
FSTL3 follistatin-like 3 (secreted glycoprotein)
G0S2 G0/G1 switch 2
GATA6 GATA binding protein 6
GIF gastric intrinsic factor (vitamin B synthesis)
GNL1 guanine nucleotide binding protein-like 1
GPATCH2L G patch domain containing 2-like
GRB7 growth factor receptor-bound protein 7
HAMP hepcidin antimicrobial peptide
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HPSE heparanase
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPA1L heat shock 70kDa protein 1-like
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IBSP integrin-binding sialoprotein
IFNA14 interferon, alpha 14
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPACT impact RWD domain protein
IPO8 importin 8
ITGA10 integrin, alpha 10
KDM7A lysine (K)-specific demethylase 7A
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MARC1 mitochondrial amidoxime reducing component 1
MDM4 MDM4, p53 regulator
MLPH melanophilin
MMP9 matrix metallopeptidase 9
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX2 MX dynamin-like GTPase 2
NCS1 neuronal calcium sensor 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXCT2 3-oxoacid CoA transferase 2
PLA2G15 phospholipase A2, group XV
PMP22 peripheral myelin protein 22
PRDM12 PR domain containing 12
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSKH1 protein serine kinase H1
R3HCC1L R3H domain and coiled-coil containing 1-like
RNF25 ring finger protein 25
SLC22A14 solute carrier family 22, member 14
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPATA2L spermatogenesis associated 2-like
SSBP3 single stranded DNA binding protein 3
SYNPO2L synaptopodin 2-like
TBKBP1 TBK1 binding protein 1
TBXAS1 thromboxane A synthase 1 (platelet)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLR8 toll-like receptor 8
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
VN1R1 vomeronasal 1 receptor 1
WASF3 WAS protein family, member 3
WT1-AS WT1 antisense RNA
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF350 zinc finger protein 350
ZNF528 zinc finger protein 528
ZNF665 zinc finger protein 665
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76