flupentixol-2643 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flupentixol-2643 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATF6B activating transcription factor 6 beta
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BMP1 bone morphogenetic protein 1
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML3 calmodulin-like 3
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CSRP2 cysteine and glycine-rich protein 2
CTNND2 catenin (cadherin-associated protein), delta 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSPP dentin sialophosphoprotein
EDNRA endothelin receptor type A
ENO3 enolase 3 (beta, muscle)
EWSR1 EWS RNA-binding protein 1
FAM13C family with sequence similarity 13, member C
FAS Fas cell surface death receptor
FAXDC2 fatty acid hydroxylase domain containing 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HPX hemopexin
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL36G interleukin 36, gamma
INHBC inhibin, beta C
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0125 KIAA0125
KIAA1456 KIAA1456
KIDINS220 kinase D-interacting substrate, 220kDa
KRT24 keratin 24, type I
LAMC2 laminin, gamma 2
LPIN1 lipin 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTBP2 latent transforming growth factor beta binding protein 2
MAGEA3 melanoma antigen family A3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD2 methyl-CpG binding domain protein 2
MPZ myelin protein zero
MRPS18C mitochondrial ribosomal protein S18C
MX2 MX dynamin-like GTPase 2
MYH14 myosin, heavy chain 14, non-muscle
N4BP3 NEDD4 binding protein 3
NCS1 neuronal calcium sensor 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEURL1 neuralized E3 ubiquitin protein ligase 1
NGLY1 N-glycanase 1
NKX2-5 NK2 homeobox 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLXNB3 plexin B3
POLG polymerase (DNA directed), gamma
PRB1 proline-rich protein BstNI subfamily 1
RAB6B RAB6B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTN2 reticulon 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STOML1 stomatin (EPB72)-like 1
TAPBP TAP binding protein (tapasin)
TBC1D2B TBC1 domain family, member 2B
TDRD3 tudor domain containing 3
THY1 Thy-1 cell surface antigen
TMPRSS2 transmembrane protease, serine 2
UBOX5 U-box domain containing 5
UTRN utrophin
VSNL1 visinin-like 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WSCD1 WSC domain containing 1
YIPF2 Yip1 domain family, member 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C22ORF46 chromosome 22 open reading frame 46
C2ORF44 chromosome 2 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CCDC134 coiled-coil domain containing 134
CCDC85C coiled-coil domain containing 85C
CD79B CD79b molecule, immunoglobulin-associated beta
CEP97 centrosomal protein 97kDa
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP13 dual specificity phosphatase 13
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EVA1B eva-1 homolog B (C. elegans)
EXO5 exonuclease 5
FAM189B family with sequence similarity 189, member B
FBRS fibrosin
FCHSD2 FCH and double SH3 domains 2
FER fer (fps/fes related) tyrosine kinase
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FOXJ2 forkhead box J2
FPGS folylpolyglutamate synthase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HIRA histone cell cycle regulator
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT22 intraflagellar transport 22
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLF3 Kruppel-like factor 3 (basic)
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LINS lines homolog (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NT5E 5'-nucleotidase, ecto (CD73)
OLFML2A olfactomedin-like 2A
PDIA3 protein disulfide isomerase family A, member 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCOR3 REST corepressor 3
ROM1 retinal outer segment membrane protein 1
SAA4 serum amyloid A4, constitutive
SH2D4A SH2 domain containing 4A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A6 solute carrier family 16, member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC46A3 solute carrier family 46, member 3
SPRYD7 SPRY domain containing 7
STAG3 stromal antigen 3
SUN2 Sad1 and UNC84 domain containing 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D17 TBC1 domain family, member 17
TCHH trichohyalin
TCTA T-cell leukemia translocation altered
TMEM180 transmembrane protein 180
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNRC6B trinucleotide repeat containing 6B
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2W ubiquitin-conjugating enzyme E2W (putative)
USP27X ubiquitin specific peptidase 27, X-linked
USP36 ubiquitin specific peptidase 36
WDR25 WD repeat domain 25
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZMYM3 zinc finger, MYM-type 3
ZNF324 zinc finger protein 324
ZNF446 zinc finger protein 446
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF701 zinc finger protein 701
ZNF74 zinc finger protein 74