fluorometholone-2509 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fluorometholone-2509 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACO2 aconitase 2, mitochondrial
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADORA3 adenosine A3 receptor
ADTRP androgen-dependent TFPI-regulating protein
AGGF1 angiogenic factor with G patch and FHA domains 1
APOA1 apolipoprotein A-I
AREG amphiregulin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPH aspartate beta-hydroxylase
B9D1 B9 protein domain 1
C4BPA complement component 4 binding protein, alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK5 docking protein 5
DUSP1 dual specificity phosphatase 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENPEP glutamyl aminopeptidase (aminopeptidase A)
F2RL3 coagulation factor II (thrombin) receptor-like 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FDPS farnesyl diphosphate synthase
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
GPR35 G protein-coupled receptor 35
GZMK granzyme K (granzyme 3; tryptase II)
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC11 histone deacetylase 11
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRK harakiri, BCL2 interacting protein
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IGH immunoglobulin heavy locus
IL13RA1 interleukin 13 receptor, alpha 1
IL1R2 interleukin 1 receptor, type II
IQCK IQ motif containing K
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLF9 Kruppel-like factor 9
KLHL20 kelch-like family member 20
KLK10 kallikrein-related peptidase 10
KRT9 keratin 9, type I
LAMA4 laminin, alpha 4
LDB3 LIM domain binding 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTBP2 latent transforming growth factor beta binding protein 2
MANSC1 MANSC domain containing 1
MARC1 mitochondrial amidoxime reducing component 1
MEG3 maternally expressed 3 (non-protein coding)
MET MET proto-oncogene, receptor tyrosine kinase
METTL7A methyltransferase like 7A
MISP mitotic spindle positioning
MPPE1 metallophosphoesterase 1
MTRF1L mitochondrial translational release factor 1-like
MTSS1 metastasis suppressor 1
NCAM1 neural cell adhesion molecule 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OMD osteomodulin
OXCT2 3-oxoacid CoA transferase 2
PAX7 paired box 7
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PER1 period circadian clock 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLSCR3 phospholipid scramblase 3
PRDM14 PR domain containing 14
PRKCQ protein kinase C, theta
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RAB26 RAB26, member RAS oncogene family
RAD51B RAD51 paralog B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBBP9 retinoblastoma binding protein 9
RGS5 regulator of G-protein signaling 5
RHOH ras homolog family member H
RUNX1 runt-related transcription factor 1
SDC2 syndecan 2
SEC14L1 SEC14-like 1 (S. cerevisiae)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH2D1A SH2 domain containing 1A
SSPN sarcospan
SVIL supervillin
SYCP1 synaptonemal complex protein 1
TAT tyrosine aminotransferase
THBS1 thrombospondin 1
TRH thyrotropin-releasing hormone
TRO trophinin
TSC22D3 TSC22 domain family, member 3
TSPAN6 tetraspanin 6
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRA3 adhesion G protein-coupled receptor A3
ANKRD55 ankyrin repeat domain 55
ARHGAP12 Rho GTPase activating protein 12
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASB7 ankyrin repeat and SOCS box containing 7
AXIN1 axin 1
C11ORF30 chromosome 11 open reading frame 30
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CCDC176 coiled-coil domain containing 176
CCL2 chemokine (C-C motif) ligand 2
CDK20 cyclin-dependent kinase 20
CORT cortistatin
CTNNBIP1 catenin, beta interacting protein 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DENND1A DENN/MADD domain containing 1A
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRAM1 DNA-damage regulated autophagy modulator 1
ECM1 extracellular matrix protein 1
ELP6 elongator acetyltransferase complex subunit 6
ENAH enabled homolog (Drosophila)
FAM188A family with sequence similarity 188, member A
FAM204A family with sequence similarity 204, member A
FAM63A family with sequence similarity 63, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FICD FIC domain containing
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAMP hepcidin antimicrobial peptide
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HHLA3 HERV-H LTR-associating 3
HSPA1L heat shock 70kDa protein 1-like
HYAL2 hyaluronoglucosaminidase 2
IL1B interleukin 1, beta
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIF1B kinesin family member 1B
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOC100287590 uncharacterized LOC100287590
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
LZTFL1 leucine zipper transcription factor-like 1
MAGEF1 melanoma antigen family F1
MBTD1 mbt domain containing 1
MCOLN1 mucolipin 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTERF1 mitochondrial transcription termination factor 1
MTG1 mitochondrial ribosome-associated GTPase 1
MYBBP1A MYB binding protein (P160) 1a
MYH15 myosin, heavy chain 15
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NBEAL2 neurobeachin-like 2
NCS1 neuronal calcium sensor 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NPIPB3 nuclear pore complex interacting protein family, member B3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARG poly (ADP-ribose) glycohydrolase
PBX3 pre-B-cell leukemia homeobox 3
PLA2G15 phospholipase A2, group XV
PODXL2 podocalyxin-like 2
RPA4 replication protein A4, 30kDa
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRAS related RAS viral (r-ras) oncogene homolog
SCML1 sex comb on midleg-like 1 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SIK1 salt-inducible kinase 1
SPATA20 spermatogenesis associated 20
SPATA2L spermatogenesis associated 2-like
SPATA7 spermatogenesis associated 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STBD1 starch binding domain 1
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
THBS4 thrombospondin 4
TMEM212 transmembrane protein 212
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNIP1 TNFAIP3 interacting protein 1
TSPAN13 tetraspanin 13
TSSC4 tumor suppressing subtransferable candidate 4
UNC13B unc-13 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZC2HC1A zinc finger, C2HC-type containing 1A
ZC3H3 zinc finger CCCH-type containing 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF696 zinc finger protein 696