fluocinonide-4314 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the fluocinonide-4314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTSL4 ADAMTS-like 4
ADGRG1 adhesion G protein-coupled receptor G1
AIRE autoimmune regulator
AKR1C1 aldo-keto reductase family 1, member C1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOXE3 arachidonate lipoxygenase 3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARSD arylsulfatase D
ASAP1-IT1 ASAP1 intronic transcript 1
BCL2L1 BCL2-like 1
CD34 CD34 molecule
COPZ2 coatomer protein complex, subunit zeta 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CYTH3 cytohesin 3
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DKFZP434C153 DKFZP434C153 protein
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
EFNB2 ephrin-B2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPAS1 endothelial PAS domain protein 1
FBXO31 F-box protein 31
FGFR4 fibroblast growth factor receptor 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP5 FK506 binding protein 5
FLT1 fms-related tyrosine kinase 1
GATA2 GATA binding protein 2
GJA4 gap junction protein, alpha 4, 37kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR137 G protein-coupled receptor 137
GPR27 G protein-coupled receptor 27
GZMK granzyme K (granzyme 3; tryptase II)
H2AFX H2A histone family, member X
HRK harakiri, BCL2 interacting protein
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSF1 heat shock transcription factor 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFFO1 intermediate filament family orphan 1
IL6R interleukin 6 receptor
INO80B INO80 complex subunit B
ITGB4 integrin, beta 4
ITPK1 inositol-tetrakisphosphate 1-kinase
JADE2 jade family PHD finger 2
JUND jun D proto-oncogene
KLHL4 kelch-like family member 4
KRT6A keratin 6A, type II
LAD1 ladinin 1
LAX1 lymphocyte transmembrane adaptor 1
LRRC75B leucine rich repeat containing 75B
LY6G6C lymphocyte antigen 6 complex, locus G6C
MARK2 MAP/microtubule affinity-regulating kinase 2
MCL1 myeloid cell leukemia 1
MED25 mediator complex subunit 25
MINK1 misshapen-like kinase 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOBP myelin-associated oligodendrocyte basic protein
MPL MPL proto-oncogene, thrombopoietin receptor
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NAV2 neuron navigator 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEURL1 neuralized E3 ubiquitin protein ligase 1
NNMT nicotinamide N-methyltransferase
NT5M 5',3'-nucleotidase, mitochondrial
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PER1 period circadian clock 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLAT plasminogen activator, tissue
PLIN2 perilipin 2
PODNL1 podocan-like 1
POLM polymerase (DNA directed), mu
POU2F2 POU class 2 homeobox 2
PRDX2 peroxiredoxin 2
RARG retinoic acid receptor, gamma
RGS5 regulator of G-protein signaling 5
RORC RAR-related orphan receptor C
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3D21 SH3 domain containing 21
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAI2 snail family zinc finger 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRT serrate, RNA effector molecule
SRSF7 serine/arginine-rich splicing factor 7
SV2B synaptic vesicle glycoprotein 2B
TGM2 transglutaminase 2
TMEM206 transmembrane protein 206
TRIM25 tripartite motif containing 25
TRIM3 tripartite motif containing 3
UNC93B1 unc-93 homolog B1 (C. elegans)
XIST X inactive specific transcript (non-protein coding)
ZNF37BP zinc finger protein 37B, pseudogene
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ATAD2B ATPase family, AAA domain containing 2B
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BEND5 BEN domain containing 5
BEX1 brain expressed, X-linked 1
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF79 chromosome 14 open reading frame 79
C19ORF40 chromosome 19 open reading frame 40
C1ORF54 chromosome 1 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CCDC71 coiled-coil domain containing 71
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKL3 cyclin-dependent kinase-like 3
CDKN2AIP CDKN2A interacting protein
CLDN1 claudin 1
CLEC2B C-type lectin domain family 2, member B
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORT cortistatin
CRMP1 collapsin response mediator protein 1
CTC1 CTS telomere maintenance complex component 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
DPF3 D4, zinc and double PHD fingers, family 3
DUSP8 dual specificity phosphatase 8
ERO1LB ERO1-like beta (S. cerevisiae)
FLCN folliculin
FMOD fibromodulin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
GAS8 growth arrest-specific 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GREB1L growth regulation by estrogen in breast cancer-like
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM5 glutathione S-transferase mu 5
HAUS6 HAUS augmin-like complex, subunit 6
HOXA4 homeobox A4
HOXC11 homeobox C11
IDI2-AS1 IDI2 antisense RNA 1
IL17RB interleukin 17 receptor B
IL1B interleukin 1, beta
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KIAA1551 KIAA1551
LMO7 LIM domain 7
LPAR6 lysophosphatidic acid receptor 6
LRRC37A3 leucine rich repeat containing 37, member A3
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MMRN2 multimerin 2
NDP Norrie disease (pseudoglioma)
NECAP2 NECAP endocytosis associated 2
NPY1R neuropeptide Y receptor Y1
NTSR1 neurotensin receptor 1 (high affinity)
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARP6 poly (ADP-ribose) polymerase family, member 6
PC pyruvate carboxylase
PDE12 phosphodiesterase 12
PGPEP1 pyroglutamyl-peptidase I
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRAMEF11 PRAME family member 11
PRPH peripherin
PRSS53 protease, serine, 53
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SERGEF secretion regulating guanine nucleotide exchange factor
SLC38A10 solute carrier family 38, member 10
SLC46A3 solute carrier family 46, member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAGLN3 transgelin 3
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMCC2 transmembrane and coiled-coil domain family 2
TMEM62 transmembrane protein 62
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TXK TXK tyrosine kinase
UBTD1 ubiquitin domain containing 1
VEZT vezatin, adherens junctions transmembrane protein
VGLL3 vestigial-like family member 3
WDR25 WD repeat domain 25
ZNF264 zinc finger protein 264
ZNF415 zinc finger protein 415
ZNF426 zinc finger protein 426
ZNF480 zinc finger protein 480
ZNF652 zinc finger protein 652