flunixin-4735 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flunixin-4735 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ALS2CL ALS2 C-terminal like
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP24 Rho GTPase activating protein 24
ARMC4 armadillo repeat containing 4
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
C3ORF18 chromosome 3 open reading frame 18
CCDC28B coiled-coil domain containing 28B
CCDC64 coiled-coil domain containing 64
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CEP295 centrosomal protein 295kDa
CLMN calmin (calponin-like, transmembrane)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNS cystinosin, lysosomal cystine transporter
CYTH4 cytohesin 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPHB4 EPH receptor B4
FAIM2 Fas apoptotic inhibitory molecule 2
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF13 fibroblast growth factor 13
FGFR1 fibroblast growth factor receptor 1
FRMD4B FERM domain containing 4B
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPM6B glycoprotein M6B
GPR153 G protein-coupled receptor 153
GREB1L growth regulation by estrogen in breast cancer-like
GRPR gastrin-releasing peptide receptor
GSK3A glycogen synthase kinase 3 alpha
GYPB glycophorin B (MNS blood group)
HFE hemochromatosis
HIC2 hypermethylated in cancer 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSF1 heat shock transcription factor 1
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA1654 KIAA1654 protein
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT9 keratin 9, type I
MAPK7 mitogen-activated protein kinase 7
MED31 mediator complex subunit 31
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP25 matrix metallopeptidase 25
MORN1 MORN repeat containing 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NF1 neurofibromin 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRF1 nuclear respiratory factor 1
OTOR otoraplin
PAX5 paired box 5
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POU5F1B POU class 5 homeobox 1B
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABGAP1 RAB GTPase activating protein 1
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RHEB Ras homolog enriched in brain
RIMS3 regulating synaptic membrane exocytosis 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SDS serine dehydratase
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLMO1 slowmo homolog 1 (Drosophila)
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPEG SPEG complex locus
SUGP1 SURP and G patch domain containing 1
TBC1D2 TBC1 domain family, member 2
TBC1D22B TBC1 domain family, member 22B
TBXA2R thromboxane A2 receptor
TCP10 t-complex 10
TDRD12 tudor domain containing 12
THAP3 THAP domain containing, apoptosis associated protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPMT thiopurine S-methyltransferase
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
WSB1 WD repeat and SOCS box containing 1
YIPF6 Yip1 domain family, member 6
ZFPL1 zinc finger protein-like 1
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTL8 actin-like 8
AGMAT agmatine ureohydrolase (agmatinase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
BAX BCL2-associated X protein
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPG capping protein (actin filament), gelsolin-like
CCDC68 coiled-coil domain containing 68
CCRL2 chemokine (C-C motif) receptor-like 2
CEL carboxyl ester lipase
CLEC7A C-type lectin domain family 7, member A
COL9A2 collagen, type IX, alpha 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNM3 dynamin 3
DUSP2 dual specificity phosphatase 2
ELSPBP1 epididymal sperm binding protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EXD3 exonuclease 3'-5' domain containing 3
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP10 FK506 binding protein 10, 65 kDa
FOXN2 forkhead box N2
GADD45G growth arrest and DNA-damage-inducible, gamma
GALK1 galactokinase 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA1456 KIAA1456
KPNA5 karyopherin alpha 5 (importin alpha 6)
LARP6 La ribonucleoprotein domain family, member 6
LAX1 lymphocyte transmembrane adaptor 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MSI1 musashi RNA-binding protein 1
MTCP1 mature T-cell proliferation 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD4 neuronal differentiation 4
NNAT neuronatin
NT5E 5'-nucleotidase, ecto (CD73)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OVOL1 ovo-like zinc finger 1
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PDIA3 protein disulfide isomerase family A, member 3
PGR progesterone receptor
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
QPCTL glutaminyl-peptide cyclotransferase-like
RAB33B RAB33B, member RAS oncogene family
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SELL selectin L
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLIT2 slit homolog 2 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STMN3 stathmin-like 3
STON1 stonin 1
STX5 syntaxin 5
TARP TCR gamma alternate reading frame protein
TBX3 T-box 3
TCTA T-cell leukemia translocation altered
THAP7 THAP domain containing 7
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPST2 tyrosylprotein sulfotransferase 2
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
WDR33 WD repeat domain 33
ZNF205 zinc finger protein 205
ZNF480 zinc finger protein 480
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862