flunixin-4273 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the flunixin-4273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADORA1 adenosine A1 receptor
ALDOB aldolase B, fructose-bisphosphate
AMPD1 adenosine monophosphate deaminase 1
AOC3 amine oxidase, copper containing 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARTN artemin
ATP10A ATPase, class V, type 10A
CABIN1 calcineurin binding protein 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM1 cell adhesion molecule 1
CCL8 chemokine (C-C motif) ligand 8
CD22 CD22 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD6 CD6 molecule
CDRT1 CMT1A duplicated region transcript 1
CHD2 chromodomain helicase DNA binding protein 2
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CORO2B coronin, actin binding protein, 2B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTC1 CREB regulated transcription coactivator 1
CRYGC crystallin, gamma C
CST4 cystatin S
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DLX2 distal-less homeobox 2
DNAI2 dynein, axonemal, intermediate chain 2
EPN1 epsin 1
FAM174B family with sequence similarity 174, member B
FGF6 fibroblast growth factor 6
FLJ11710 uncharacterized protein FLJ11710
FLT3 fms-related tyrosine kinase 3
FRMD8 FERM domain containing 8
FSCN3 fascin actin-bundling protein 3, testicular
GC group-specific component (vitamin D binding protein)
GJA4 gap junction protein, alpha 4, 37kDa
GPR20 G protein-coupled receptor 20
GREB1L growth regulation by estrogen in breast cancer-like
GRK4 G protein-coupled receptor kinase 4
HCRTR2 hypocretin (orexin) receptor 2
HHAT hedgehog acyltransferase
HPS1 Hermansky-Pudlak syndrome 1
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IRF4 interferon regulatory factor 4
KRTAP5-9 keratin associated protein 5-9
LIME1 Lck interacting transmembrane adaptor 1
LIPE lipase, hormone-sensitive
LMOD1 leiomodin 1 (smooth muscle)
LRP1 low density lipoprotein receptor-related protein 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCF2L MCF.2 cell line derived transforming sequence-like
MLN motilin
MUC3A mucin 3A, cell surface associated
NIPAL2 NIPA-like domain containing 2
NLE1 notchless homolog 1 (Drosophila)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PCDHGA11 protocadherin gamma subfamily A, 11
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLEK pleckstrin
PMP2 peripheral myelin protein 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROSC proline synthetase co-transcribed homolog (bacterial)
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIS prostaglandin I2 (prostacyclin) synthase
PXN paxillin
RAB6B RAB6B, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RGS16 regulator of G-protein signaling 16
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC14L4 SEC14-like 4 (S. cerevisiae)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SORBS3 sorbin and SH3 domain containing 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTBN5 spectrin, beta, non-erythrocytic 5
SSX1 synovial sarcoma, X breakpoint 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TBL1Y transducin (beta)-like 1, Y-linked
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TM4SF20 transmembrane 4 L six family member 20
TRIM3 tripartite motif containing 3
TULP2 tubby like protein 2
YBX2 Y box binding protein 2
ZFPL1 zinc finger protein-like 1
ZNF117 zinc finger protein 117
ZNF609 zinc finger protein 609
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARSJ arylsulfatase family, member J
ASB7 ankyrin repeat and SOCS box containing 7
CCNJL cyclin J-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CFAP44 cilia and flagella associated protein 44
COA7 cytochrome c oxidase assembly factor 7 (putative)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL6 chemokine (C-X-C motif) ligand 6
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLL3 delta-like 3 (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSC2 desmocollin 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM204A family with sequence similarity 204, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLTP glycolipid transfer protein
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4C histone cluster 1, H4c
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOXC4 homeobox C4
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
IL33 interleukin 33
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIFC1 kinesin family member C1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MFSD6 major facilitator superfamily domain containing 6
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MIS18BP1 MIS18 binding protein 1
MTERF4 mitochondrial transcription termination factor 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OSMR oncostatin M receptor
PBLD phenazine biosynthesis-like protein domain containing
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHF14 PHD finger protein 14
PLA2G12A phospholipase A2, group XIIA
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBBP5 retinoblastoma binding protein 5
RFX7 regulatory factor X, 7
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS14P3 ribosomal protein S14 pseudogene 3
RSRC1 arginine/serine-rich coiled-coil 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPATS2 spermatogenesis associated, serine-rich 2
SPIDR scaffolding protein involved in DNA repair
SPIN1 spindlin 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBXN8 UBX domain protein 8
USP27X ubiquitin specific peptidase 27, X-linked
WWC2 WW and C2 domain containing 2
ZBED1 zinc finger, BED-type containing 1
ZBTB24 zinc finger and BTB domain containing 24
ZC3H12A zinc finger CCCH-type containing 12A
ZFP69B ZFP69 zinc finger protein B
ZNF264 zinc finger protein 264
ZNF468 zinc finger protein 468
ZNF492 zinc finger protein 492
ZNF529 zinc finger protein 529
ZNF652 zinc finger protein 652
ZNF667 zinc finger protein 667