flumetasone-4734 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flumetasone-4734 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADRBK2 adrenergic, beta, receptor kinase 2
AGFG1 ArfGAP with FG repeats 1
AHNAK2 AHNAK nucleoprotein 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7IP activating transcription factor 7 interacting protein
AVPR1B arginine vasopressin receptor 1B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL6 B-cell CLL/lymphoma 6
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C1ORF54 chromosome 1 open reading frame 54
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CCDC33 coiled-coil domain containing 33
CD22 CD22 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP295 centrosomal protein 295kDa
CLTB clathrin, light chain B
CNOT2 CCR4-NOT transcription complex, subunit 2
COPZ2 coatomer protein complex, subunit zeta 2
CTSF cathepsin F
CYBB cytochrome b-245, beta polypeptide
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DTX2 deltex 2, E3 ubiquitin ligase
EMP1 epithelial membrane protein 1
FERMT2 fermitin family member 2
FRMD8 FERM domain containing 8
FSTL3 follistatin-like 3 (secreted glycoprotein)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLP1R glucagon-like peptide 1 receptor
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR85 G protein-coupled receptor 85
GREB1L growth regulation by estrogen in breast cancer-like
GRM7 glutamate receptor, metabotropic 7
HDAC11 histone deacetylase 11
HIPK3 homeodomain interacting protein kinase 3
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IL2RG interleukin 2 receptor, gamma
IRF4 interferon regulatory factor 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF9 Kruppel-like factor 9
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMB4 laminin, beta 4
LOC100287387 uncharacterized LOC100287387
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEC1 melanoma antigen family C1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK7 mitogen-activated protein kinase 7
MCPH1 microcephalin 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPL MPL proto-oncogene, thrombopoietin receptor
MR1 major histocompatibility complex, class I-related
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUC3A mucin 3A, cell surface associated
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NGDN neuroguidin, EIF4E binding protein
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH1 protocadherin 1
PDE5A phosphodiesterase 5A, cGMP-specific
PER1 period circadian clock 1
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PON1 paraoxonase 1
PQLC3 PQ loop repeat containing 3
PRKCA protein kinase C, alpha
PSCA prostate stem cell antigen
PTCRA pre T-cell antigen receptor alpha
PTGES prostaglandin E synthase
REEP2 receptor accessory protein 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOBTB2 Rho-related BTB domain containing 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RYR2 ryanodine receptor 2 (cardiac)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORBS2 sorbin and SH3 domain containing 2
SYNC syncoilin, intermediate filament protein
TEX40 testis expressed 40
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THOC5 THO complex 5
TJAP1 tight junction associated protein 1 (peripheral)
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
USP46 ubiquitin specific peptidase 46
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTL8 actin-like 8
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D2 B9 protein domain 2
BMP4 bone morphogenetic protein 4
C19ORF40 chromosome 19 open reading frame 40
C22ORF29 chromosome 22 open reading frame 29
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC68 coiled-coil domain containing 68
CCDC69 coiled-coil domain containing 69
CCDC85C coiled-coil domain containing 85C
CENPO centromere protein O
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CNGB3 cyclic nucleotide gated channel beta 3
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNM3 dynamin 3
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
ERCC5 excision repair cross-complementation group 5
FAM110B family with sequence similarity 110, member B
FAM131A family with sequence similarity 131, member A
FAM204A family with sequence similarity 204, member A
FANCE Fanconi anemia, complementation group E
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FKRP fukutin related protein
GADD45G growth arrest and DNA-damage-inducible, gamma
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPATCH2L G patch domain containing 2-like
GPR27 G protein-coupled receptor 27
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HOXC13 homeobox C13
HPS6 Hermansky-Pudlak syndrome 6
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
KIAA0754 KIAA0754
KIAA1456 KIAA1456
LIG4 ligase IV, DNA, ATP-dependent
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MNX1 motor neuron and pancreas homeobox 1
MXD3 MAX dimerization protein 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD4 neuronal differentiation 4
NNAT neuronatin
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPFFR1 neuropeptide FF receptor 1
OLFML2A olfactomedin-like 2A
ONECUT1 one cut homeobox 1
PCDHA5 protocadherin alpha 5
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGB5 protocadherin gamma subfamily B, 5
PEX26 peroxisomal biogenesis factor 26
PGR progesterone receptor
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
PRR14L proline rich 14-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPA4 replication protein A4, 30kDa
RPAP1 RNA polymerase II associated protein 1
S100A2 S100 calcium binding protein A2
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SOCS2 suppressor of cytokine signaling 2
SPINK5 serine peptidase inhibitor, Kazal type 5
STON1 stonin 1
STX1A syntaxin 1A (brain)
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM66 tripartite motif containing 66
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBQLN4 ubiquilin 4
USP19 ubiquitin specific peptidase 19
XYLT1 xylosyltransferase I
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF442 zinc finger protein 442
ZNF668 zinc finger protein 668