flufenamic acid-5478 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the flufenamic acid-5478 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAM7 ADAM metallopeptidase domain 7
ADCY1 adenylate cyclase 1 (brain)
AGTR1 angiotensin II receptor, type 1
ALS2CL ALS2 C-terminal like
APOM apolipoprotein M
ARC activity-regulated cytoskeleton-associated protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARL4C ADP-ribosylation factor-like 4C
AVPR1B arginine vasopressin receptor 1B
BTF3P11 basic transcription factor 3 pseudogene 11
CASD1 CAS1 domain containing 1
CCDC71 coiled-coil domain containing 71
CD52 CD52 molecule
CD86 CD86 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLCA2 chloride channel accessory 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COL10A1 collagen, type X, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRABP1 cellular retinoic acid binding protein 1
CREBZF CREB/ATF bZIP transcription factor
CRTC1 CREB regulated transcription coactivator 1
CTBP2 C-terminal binding protein 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DLK2 delta-like 2 homolog (Drosophila)
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
FAM160B2 family with sequence similarity 160, member B2
FBLN1 fibulin 1
FH fumarate hydratase
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAR1 GAR1 ribonucleoprotein
GIF gastric intrinsic factor (vitamin B synthesis)
GLS glutaminase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC4 glypican 4
GSTP1 glutathione S-transferase pi 1
GTDC1 glycosyltransferase-like domain containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HFE hemochromatosis
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
IFT140 intraflagellar transport 140
IL1RAP interleukin 1 receptor accessory protein
JAM3 junctional adhesion molecule 3
KIAA0125 KIAA0125
KIAA0754 KIAA0754
KRT23 keratin 23, type I
LAMC2 laminin, gamma 2
LIG4 ligase IV, DNA, ATP-dependent
LINC00597 long intergenic non-protein coding RNA 597
LRP12 low density lipoprotein receptor-related protein 12
LRRC61 leucine rich repeat containing 61
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAX MYC associated factor X
MCC mutated in colorectal cancers
MYL10 myosin, light chain 10, regulatory
MYOF myoferlin
N4BP3 NEDD4 binding protein 3
NPPA natriuretic peptide A
NRIP3 nuclear receptor interacting protein 3
OCLM oculomedin
PEG10 paternally expressed 10
PKNOX2 PBX/knotted 1 homeobox 2
PLXNC1 plexin C1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD51 RAD51 recombinase
RELN reelin
RREB1 ras responsive element binding protein 1
S100A9 S100 calcium binding protein A9
SAP30 Sin3A-associated protein, 30kDa
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT3 sirtuin 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOD2 superoxide dismutase 2, mitochondrial
STX3 syntaxin 3
STX7 syntaxin 7
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBX1 T-box 1
TMEM259 transmembrane protein 259
TSSK2 testis-specific serine kinase 2
TUBB1 tubulin, beta 1 class VI
UHRF1BP1L UHRF1 binding protein 1-like
WDFY3 WD repeat and FYVE domain containing 3
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF286A zinc finger protein 286A
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AES amino-terminal enhancer of split
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATAD2B ATPase family, AAA domain containing 2B
ATAD3A ATPase family, AAA domain containing 3A
ATP13A2 ATPase type 13A2
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C14ORF132 chromosome 14 open reading frame 132
CALCOCO1 calcium binding and coiled-coil domain 1
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CHML choroideremia-like (Rab escort protein 2)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN4 claudin 4
CLDN9 claudin 9
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CUEDC1 CUE domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EIF5A2 eukaryotic translation initiation factor 5A2
ELP3 elongator acetyltransferase complex subunit 3
FBXL15 F-box and leucine-rich repeat protein 15
FOSL1 FOS-like antigen 1
GLI3 GLI family zinc finger 3
GPKOW G patch domain and KOW motifs
GPX2 glutathione peroxidase 2
HIST1H2BJ histone cluster 1, H2bj
HMOX1 heme oxygenase 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKB inositol-trisphosphate 3-kinase B
KLHL36 kelch-like family member 36
LINS lines homolog (Drosophila)
LMCD1 LIM and cysteine-rich domains 1
LRP5 low density lipoprotein receptor-related protein 5
LSR lipolysis stimulated lipoprotein receptor
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP9 microtubule-associated protein 9
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
MEIS1 Meis homeobox 1
METTL1 methyltransferase like 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
NES nestin
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5C 5', 3'-nucleotidase, cytosolic
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDLIM2 PDZ and LIM domain 2 (mystique)
PLA2G15 phospholipase A2, group XV
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN3 perilipin 3
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
PYGB phosphorylase, glycogen; brain
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REEP4 receptor accessory protein 4
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMHD1 SAM domain and HD domain 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETMAR SET domain and mariner transposase fusion gene
SIK1 salt-inducible kinase 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC35F5 solute carrier family 35, member F5
SND1 staphylococcal nuclease and tudor domain containing 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAGLN transgelin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TEAD3 TEA domain family member 3
TESC tescalcin
TESK2 testis-specific kinase 2
TEX264 testis expressed 264
TMC7 transmembrane channel-like 7
TMEM183A transmembrane protein 183A
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF696 zinc finger protein 696
ZSCAN26 zinc finger and SCAN domain containing 26