flufenamic acid-5059 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the flufenamic acid-5059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOT11 acyl-CoA thioesterase 11
ADAM23 ADAM metallopeptidase domain 23
ALB albumin
APC2 adenomatosis polyposis coli 2
ARHGAP35 Rho GTPase activating protein 35
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATN1 atrophin 1
ATP9A ATPase, class II, type 9A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CABP1 calcium binding protein 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARTPT CART prepropeptide
CD4 CD4 molecule
CD58 CD58 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDRT1 CMT1A duplicated region transcript 1
CEP135 centrosomal protein 135kDa
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN17 claudin 17
CNGB3 cyclic nucleotide gated channel beta 3
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CREB3L1 cAMP responsive element binding protein 3-like 1
CRHR2 corticotropin releasing hormone receptor 2
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR2 chemokine (C-X-C motif) receptor 2
DAPK3 death-associated protein kinase 3
DCTN1 dynactin 1
DDN dendrin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH2 diaphanous-related formin 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK10 dedicator of cytokinesis 10
DRD2 dopamine receptor D2
DRP2 dystrophin related protein 2
DTX3 deltex 3, E3 ubiquitin ligase
ECM1 extracellular matrix protein 1
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ELK1 ELK1, member of ETS oncogene family
ESRRG estrogen-related receptor gamma
FAM134B family with sequence similarity 134, member B
FGB fibrinogen beta chain
FMO5 flavin containing monooxygenase 5
FSCN3 fascin actin-bundling protein 3, testicular
GJA8 gap junction protein, alpha 8, 50kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HBZ hemoglobin, zeta
ICAM1 intercellular adhesion molecule 1
IRX5 iroquois homeobox 5
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIFC3 kinesin family member C3
KYNU kynureninase
LEF1 lymphoid enhancer-binding factor 1
LRP2 low density lipoprotein receptor-related protein 2
MAPK10 mitogen-activated protein kinase 10
MDFIC MyoD family inhibitor domain containing
MIR622 microRNA 622
MMP11 matrix metallopeptidase 11
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
MYBPC3 myosin binding protein C, cardiac
MYRIP myosin VIIA and Rab interacting protein
MYT1 myelin transcription factor 1
ONECUT2 one cut homeobox 2
PLAG1 pleiomorphic adenoma gene 1
PPARD peroxisome proliferator-activated receptor delta
PRSS50 protease, serine, 50
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGDR2 prostaglandin D2 receptor 2
PTPRR protein tyrosine phosphatase, receptor type, R
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF126P1 ring finger protein 126 pseudogene 1
RUNX1 runt-related transcription factor 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLA Src-like-adaptor
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO2B1 solute carrier organic anion transporter family, member 2B1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRA T cell receptor alpha locus
UNC93A unc-93 homolog A (C. elegans)
WDR25 WD repeat domain 25
XAF1 XIAP associated factor 1
XCR1 chemokine (C motif) receptor 1
ZFHX2 zinc finger homeobox 2
ZNF224 zinc finger protein 224
ZNF259P1 zinc finger protein 259 pseudogene 1
ZNF287 zinc finger protein 287
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD17B abhydrolase domain containing 17B
ACVR2B activin A receptor, type IIB
ADGRF1 adhesion G protein-coupled receptor F1
APH1B APH1B gamma secretase subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BAG4 BCL2-associated athanogene 4
BAK1 BCL2-antagonist/killer 1
BTC betacellulin
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CDT1 chromatin licensing and DNA replication factor 1
CEP112 centrosomal protein 112kDa
CFAP69 cilia and flagella associated protein 69
CHMP6 charged multivesicular body protein 6
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPED1 cadherin-like and PC-esterase domain containing 1
CSF1R colony stimulating factor 1 receptor
CTNNBL1 catenin, beta like 1
DENND4A DENN/MADD domain containing 4A
ECE1 endothelin converting enzyme 1
ELOVL4 ELOVL fatty acid elongase 4
EPHA4 EPH receptor A4
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVPL envoplakin
FAM160B2 family with sequence similarity 160, member B2
FAM53B family with sequence similarity 53, member B
FHOD1 formin homology 2 domain containing 1
GALE UDP-galactose-4-epimerase
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH1 G patch domain containing 1
GRAMD4 GRAM domain containing 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
H2AFJ H2A histone family, member J
HAUS6 HAUS augmin-like complex, subunit 6
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOMER2 homer scaffolding protein 2
HOXA1 homeobox A1
HOXA4 homeobox A4
IFI6 interferon, alpha-inducible protein 6
IL7 interleukin 7
KIAA0556 KIAA0556
KIAA0753 KIAA0753
KIAA0754 KIAA0754
KIAA1462 KIAA1462
KLF7 Kruppel-like factor 7 (ubiquitous)
KLK5 kallikrein-related peptidase 5
LMO7 LIM domain 7
LRRC37A3 leucine rich repeat containing 37, member A3
MAPK12 mitogen-activated protein kinase 12
MAPK3 mitogen-activated protein kinase 3
MFSD11 major facilitator superfamily domain containing 11
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYO1E myosin IE
NINJ1 ninjurin 1
NOD1 nucleotide-binding oligomerization domain containing 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PALMD palmdelphin
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRR15L proline rich 15-like
PYCRL pyrroline-5-carboxylate reductase-like
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SIRT6 sirtuin 6
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SOD3 superoxide dismutase 3, extracellular
SSBP3 single stranded DNA binding protein 3
STBD1 starch binding domain 1
STIM1 stromal interaction molecule 1
STX5 syntaxin 5
TAGLN3 transgelin 3
TRAPPC2 trafficking protein particle complex 2
TSC22D4 TSC22 domain family, member 4
UEVLD UEV and lactate/malate dehyrogenase domains
UNC119 unc-119 homolog (C. elegans)
WNT7A wingless-type MMTV integration site family, member 7A
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF137P zinc finger protein 137, pseudogene
ZNF197 zinc finger protein 197
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862