flufenamic acid-2104 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flufenamic acid-2104 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALOXE3 arachidonate lipoxygenase 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
BAX BCL2-associated X protein
BMP4 bone morphogenetic protein 4
C17ORF80 chromosome 17 open reading frame 80
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCP110 centriolar coiled coil protein 110kDa
CFAP69 cilia and flagella associated protein 69
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DCAF13 DDB1 and CUL4 associated factor 13
DRD2 dopamine receptor D2
DXO decapping exoribonuclease
EML2 echinoderm microtubule associated protein like 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA4 EYA transcriptional coactivator and phosphatase 4
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FCMR Fc fragment of IgM receptor
FGF1 fibroblast growth factor 1 (acidic)
FURIN furin (paired basic amino acid cleaving enzyme)
GAL3ST4 galactose-3-O-sulfotransferase 4
GALT galactose-1-phosphate uridylyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HIRA histone cell cycle regulator
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
IFI6 interferon, alpha-inducible protein 6
IL6ST interleukin 6 signal transducer
INO80B INO80 complex subunit B
ITGB5 integrin, beta 5
JUND jun D proto-oncogene
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0754 KIAA0754
KYNU kynureninase
LINC00341 long intergenic non-protein coding RNA 341
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LOC729164 hCG1732469
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
METTL5 methyltransferase like 5
MINK1 misshapen-like kinase 1
MOCS1 molybdenum cofactor synthesis 1
MYH15 myosin, heavy chain 15
NF2 neurofibromin 2 (merlin)
NFX1 nuclear transcription factor, X-box binding 1
NT5M 5',3'-nucleotidase, mitochondrial
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCNXL2 pecanex-like 2 (Drosophila)
PDCD6 programmed cell death 6
PDLIM4 PDZ and LIM domain 4
PER3 period circadian clock 3
PHF1 PHD finger protein 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLBD1 phospholipase B domain containing 1
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRR14L proline rich 14-like
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51B RAD51 paralog B
RARS arginyl-tRNA synthetase
RGS14 regulator of G-protein signaling 14
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RTEL1 regulator of telomere elongation helicase 1
SCARB1 scavenger receptor class B, member 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLA Src-like-adaptor
SLC17A2 solute carrier family 17, member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNORA21 small nucleolar RNA, H/ACA box 21
SORBS2 sorbin and SH3 domain containing 2
SP100 SP100 nuclear antigen
SRRM2 serine/arginine repetitive matrix 2
SSX3 synovial sarcoma, X breakpoint 3
STC1 stanniocalcin 1
SYMPK symplekin
TAOK1 TAO kinase 1
TAT tyrosine aminotransferase
TDRKH tudor and KH domain containing
THRAP3 thyroid hormone receptor associated protein 3
TMEM231 transmembrane protein 231
TNC tenascin C
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
YTHDC1 YTH domain containing 1
YY2 YY2 transcription factor
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACOX2 acyl-CoA oxidase 2, branched chain
ADCY6 adenylate cyclase 6
ADGRG2 adhesion G protein-coupled receptor G2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APLP1 amyloid beta (A4) precursor-like protein 1
BNC1 basonuclin 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF115 chromosome 1 open reading frame 115
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLCN2 chloride channel, voltage-sensitive 2
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNPY3 canopy FGF signaling regulator 3
CNTNAP1 contactin associated protein 1
CXORF56 chromosome X open reading frame 56
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DMTF1 cyclin D binding myb-like transcription factor 1
DMXL1 Dmx-like 1
EGF epidermal growth factor
EHD3 EH-domain containing 3
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FOXD1 forkhead box D1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPATCH1 G patch domain containing 1
GSDMD gasdermin D
HCFC2 host cell factor C2
HECA headcase homolog (Drosophila)
HHLA3 HERV-H LTR-associating 3
HINFP histone H4 transcription factor
HIST1H2BC histone cluster 1, H2bc
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMHA1 histocompatibility (minor) HA-1
HSF2BP heat shock transcription factor 2 binding protein
IGFLR1 IGF-like family receptor 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISYNA1 inositol-3-phosphate synthase 1
KDM4D lysine (K)-specific demethylase 4D
LRRC8E leucine rich repeat containing 8 family, member E
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPK12 mitogen-activated protein kinase 12
MFSD10 major facilitator superfamily domain containing 10
MFSD12 major facilitator superfamily domain containing 12
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOGS mannosyl-oligosaccharide glucosidase
MORC3 MORC family CW-type zinc finger 3
MOXD1 monooxygenase, DBH-like 1
MYO1D myosin ID
NCS1 neuronal calcium sensor 1
NDEL1 nudE neurodevelopment protein 1-like 1
NINL ninein-like
PAQR6 progestin and adipoQ receptor family member VI
PARM1 prostate androgen-regulated mucin-like protein 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PDZD2 PDZ domain containing 2
PHKG2 phosphorylase kinase, gamma 2 (testis)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTK6 protein tyrosine kinase 6
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RIC8B RIC8 guanine nucleotide exchange factor B
RNF216 ring finger protein 216
RPAP2 RNA polymerase II associated protein 2
RUVBL1 RuvB-like AAA ATPase 1
SAMD9 sterile alpha motif domain containing 9
SERTAD3 SERTA domain containing 3
SH2D2A SH2 domain containing 2A
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNTA1 syntrophin, alpha 1
SREBF2 sterol regulatory element binding transcription factor 2
ST5 suppression of tumorigenicity 5
TBCCD1 TBCC domain containing 1
TESK1 testis-specific kinase 1
TIPRL TOR signaling pathway regulator
TMEM184C transmembrane protein 184C
TRIM45 tripartite motif containing 45
TSPAN8 tetraspanin 8
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YIPF3 Yip1 domain family, member 3
ZBTB39 zinc finger and BTB domain containing 39
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF304 zinc finger protein 304