flufenamic acid-1420 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flufenamic acid-1420 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AIM2 absent in melanoma 2
ARSB arylsulfatase B
ATP5SL ATP5S-like
BAHCC1 BAH domain and coiled-coil containing 1
BAX BCL2-associated X protein
BCL7A B-cell CLL/lymphoma 7A
C19ORF66 chromosome 19 open reading frame 66
C2ORF27A chromosome 2 open reading frame 27A
CA14 carbonic anhydrase XIV
CAMKV CaM kinase-like vesicle-associated
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CDHR2 cadherin-related family member 2
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHERP calcium homeostasis endoplasmic reticulum protein
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL4A2 collagen, type IV, alpha 2
CPED1 cadherin-like and PC-esterase domain containing 1
CTSZ cathepsin Z
CUL5 cullin 5
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHFR dihydrofolate reductase
DNAL4 dynein, axonemal, light chain 4
DOCK5 dedicator of cytokinesis 5
DRAM1 DNA-damage regulated autophagy modulator 1
EDAR ectodysplasin A receptor
ELMO2 engulfment and cell motility 2
EML2 echinoderm microtubule associated protein like 2
FAM86B1 family with sequence similarity 86, member B1
FHL3 four and a half LIM domains 3
FNBP1 formin binding protein 1
FST follistatin
GPX2 glutathione peroxidase 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBB hemoglobin, beta
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HFE hemochromatosis
HIRA histone cell cycle regulator
HTRA2 HtrA serine peptidase 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INO80D INO80 complex subunit D
KRCC1 lysine-rich coiled-coil 1
KRT38 keratin 38, type I
LPAR1 lysophosphatidic acid receptor 1
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MCL1 myeloid cell leukemia 1
MED28 mediator complex subunit 28
MET MET proto-oncogene, receptor tyrosine kinase
N4BP1 NEDD4 binding protein 1
NDNF neuron-derived neurotrophic factor
NEU3 sialidase 3 (membrane sialidase)
NPM3 nucleophosmin/nucleoplasmin 3
NT5E 5'-nucleotidase, ecto (CD73)
OSBPL2 oxysterol binding protein-like 2
PGK1 phosphoglycerate kinase 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLD2 phospholipase D2
PLIN2 perilipin 2
PNOC prepronociceptin
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRDM11 PR domain containing 11
PRODH2 proline dehydrogenase (oxidase) 2
PRR14L proline rich 14-like
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARB retinoic acid receptor, beta
RASAL1 RAS protein activator like 1 (GAP1 like)
RHOQ ras homolog family member Q
SAP18 Sin3A-associated protein, 18kDa
SH2D2A SH2 domain containing 2A
SH3BP2 SH3-domain binding protein 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SMG5 SMG5 nonsense mediated mRNA decay factor
SPN sialophorin
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STK17B serine/threonine kinase 17b
SUGP1 SURP and G patch domain containing 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TFEB transcription factor EB
TMED1 transmembrane emp24 protein transport domain containing 1
TRABD TraB domain containing
UBE3A ubiquitin protein ligase E3A
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
YIPF1 Yip1 domain family, member 1
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADAM23 ADAM metallopeptidase domain 23
ANXA6 annexin A6
ASCC1 activating signal cointegrator 1 complex subunit 1
ASNSD1 asparagine synthetase domain containing 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN2 ataxin 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL7C B-cell CLL/lymphoma 7C
C12ORF43 chromosome 12 open reading frame 43
CASZ1 castor zinc finger 1
CD2AP CD2-associated protein
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTR1 cap methyltransferase 1
COG7 component of oligomeric golgi complex 7
CPOX coproporphyrinogen oxidase
CRY1 cryptochrome circadian clock 1
CTSL cathepsin L
CYTH2 cytohesin 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DENND4A DENN/MADD domain containing 4A
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIXDC1 DIX domain containing 1
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMXL1 Dmx-like 1
DPYD dihydropyrimidine dehydrogenase
DUSP5 dual specificity phosphatase 5
ERF Ets2 repressor factor
FBXO5 F-box protein 5
FBXW12 F-box and WD repeat domain containing 12
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FZD2 frizzled class receptor 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCHFR GTP cyclohydrolase I feedback regulator
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPN3 GPN-loop GTPase 3
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
H1FX H1 histone family, member X
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAUS2 HAUS augmin-like complex, subunit 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KIF20B kinesin family member 20B
MAGEF1 melanoma antigen family F1
MAGOHB mago-nashi homolog B (Drosophila)
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAST3 microtubule associated serine/threonine kinase 3
MGAM maltase-glucoamylase
MPHOSPH8 M-phase phosphoprotein 8
MRPL33 mitochondrial ribosomal protein L33
MT1HL1 metallothionein 1H-like 1
MXRA8 matrix-remodelling associated 8
MYL12B myosin, light chain 12B, regulatory
NABP2 nucleic acid binding protein 2
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRBP1 nuclear receptor binding protein 1
NT5DC3 5'-nucleotidase domain containing 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHACTR4 phosphatase and actin regulator 4
PLCD1 phospholipase C, delta 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PMM1 phosphomannomutase 1
POMT1 protein-O-mannosyltransferase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPIEL peptidylprolyl isomerase E-like pseudogene
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRR11 proline rich 11
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RECQL4 RecQ protein-like 4
RFWD3 ring finger and WD repeat domain 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUNX1-IT1 RUNX1 intronic transcript 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SMAD7 SMAD family member 7
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SSNA1 Sjogren syndrome nuclear autoantigen 1
STXBP3 syntaxin binding protein 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TM7SF3 transmembrane 7 superfamily member 3
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZEB2 zinc finger E-box binding homeobox 2
ZNF160 zinc finger protein 160
ZNF264 zinc finger protein 264
ZNF268 zinc finger protein 268
ZNF426 zinc finger protein 426
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669