fludrocortisone-3866 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the fludrocortisone-3866 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
AFF2 AF4/FMR2 family, member 2
AGRP agouti related neuropeptide
AHNAK AHNAK nucleoprotein
AK1 adenylate kinase 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BGN biglycan
BIRC3 baculoviral IAP repeat containing 3
C17ORF53 chromosome 17 open reading frame 53
C9ORF9 chromosome 9 open reading frame 9
CCNK cyclin K
CCR1 chemokine (C-C motif) receptor 1
CD1A CD1a molecule
CD34 CD34 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDHR2 cadherin-related family member 2
CDK12 cyclin-dependent kinase 12
CFAP45 cilia and flagella associated protein 45
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CUZD1 CUB and zona pellucida-like domains 1
CXORF21 chromosome X open reading frame 21
DHRS12 dehydrogenase/reductase (SDR family) member 12
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DRD1 dopamine receptor D1
DRICH1 aspartate-rich 1
ECE1 endothelin converting enzyme 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EMP1 epithelial membrane protein 1
EPHA5 EPH receptor A5
EPPIN epididymal peptidase inhibitor
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FKRP fukutin related protein
FN1 fibronectin 1
FZD10 frizzled class receptor 10
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALR3 galanin receptor 3
GPER1 G protein-coupled estrogen receptor 1
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTTP1 glutathione S-transferase theta pseudogene 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AB histone cluster 1, H2ab
HR hair growth associated
IL23A interleukin 23, alpha subunit p19
KLF9 Kruppel-like factor 9
LCMT2 leucine carboxyl methyltransferase 2
LOXL2 lysyl oxidase-like 2
LTK leukocyte receptor tyrosine kinase
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP2K7 mitogen-activated protein kinase kinase 7
METTL5 methyltransferase like 5
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NOL12 nucleolar protein 12
NOX1 NADPH oxidase 1
NRL neural retina leucine zipper
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDCD6 programmed cell death 6
PDGFA platelet-derived growth factor alpha polypeptide
PEX16 peroxisomal biogenesis factor 16
PICK1 protein interacting with PRKCA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLK3 polo-like kinase 3
PRF1 perforin 1 (pore forming protein)
PSCA prostate stem cell antigen
PSG11 pregnancy specific beta-1-glycoprotein 11
RARB retinoic acid receptor, beta
RASL11B RAS-like, family 11, member B
RFC1 replication factor C (activator 1) 1, 145kDa
RHOBTB2 Rho-related BTB domain containing 2
RIMS3 regulating synaptic membrane exocytosis 3
RXRB retinoid X receptor, beta
SCN1B sodium channel, voltage gated, type I beta subunit
SERHL2 serine hydrolase-like 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAI2 snail family zinc finger 2
SPON1 spondin 1, extracellular matrix protein
SPTB spectrin, beta, erythrocytic
STOML1 stomatin (EPB72)-like 1
SULT4A1 sulfotransferase family 4A, member 1
T T, brachyury homolog (mouse)
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIO trio Rho guanine nucleotide exchange factor
TSGA10 testis specific, 10
USP20 ubiquitin specific peptidase 20
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
AMH anti-Mullerian hormone
ARRB1 arrestin, beta 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C10ORF95 chromosome 10 open reading frame 95
C11ORF21 chromosome 11 open reading frame 21
C14ORF79 chromosome 14 open reading frame 79
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
C5AR2 complement component 5a receptor 2
CARF calcium responsive transcription factor
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CCDC71 coiled-coil domain containing 71
CCDC88C coiled-coil domain containing 88C
CCNO cyclin O
CD80 CD80 molecule
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CLASRP CLK4-associating serine/arginine rich protein
CLCN2 chloride channel, voltage-sensitive 2
CPTP ceramide-1-phosphate transfer protein
CSTA cystatin A (stefin A)
DAPK3 death-associated protein kinase 3
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEAF1 DEAF1 transcription factor
DOC2A double C2-like domains, alpha
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
EMCN endomucin
EMID1 EMI domain containing 1
ENO2 enolase 2 (gamma, neuronal)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM198B family with sequence similarity 198, member B
FBXO22 F-box protein 22
FKBP10 FK506 binding protein 10, 65 kDa
GDAP1 ganglioside induced differentiation associated protein 1
GEM GTP binding protein overexpressed in skeletal muscle
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR143 G protein-coupled receptor 143
HIST1H1B histone cluster 1, H1b
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFNA14 interferon, alpha 14
IGSF1 immunoglobulin superfamily, member 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL22 interleukin 22
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
LGALS4 lectin, galactoside-binding, soluble, 4
LHX1 LIM homeobox 1
LOC390998 ribosomal protein L10 pseudogene
MAVS mitochondrial antiviral signaling protein
MCOLN1 mucolipin 1
MDM4 MDM4, p53 regulator
MMP2 matrix metallopeptidase 2
MOGS mannosyl-oligosaccharide glucosidase
MRPS18C mitochondrial ribosomal protein S18C
NOL10 nucleolar protein 10
NPM3 nucleophosmin/nucleoplasmin 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN6 NOP2/Sun domain family, member 6
PEX26 peroxisomal biogenesis factor 26
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLD2 phospholipase D2
PRR14L proline rich 14-like
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF146 ring finger protein 146
RPL10L ribosomal protein L10-like
SDC3 syndecan 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLIT2 slit homolog 2 (Drosophila)
SPAG4 sperm associated antigen 4
SPON2 spondin 2, extracellular matrix protein
STARD3 StAR-related lipid transfer (START) domain containing 3
STON1 stonin 1
TGFBR3 transforming growth factor, beta receptor III
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM25 tripartite motif containing 25
TRIM68 tripartite motif containing 68
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
VIM vimentin
WDR33 WD repeat domain 33
WDR91 WD repeat domain 91
ZNF350 zinc finger protein 350
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2