fludrocortisone-3785 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fludrocortisone-3785 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADAM20 ADAM metallopeptidase domain 20
ADPRH ADP-ribosylarginine hydrolase
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOXE3 arachidonate lipoxygenase 3
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARSA arylsulfatase A
ATP10B ATPase, class V, type 10B
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CADM3 cell adhesion molecule 3
CALHM2 calcium homeostasis modulator 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL22 chemokine (C-C motif) ligand 22
CCR7 chemokine (C-C motif) receptor 7
CDHR2 cadherin-related family member 2
CFH complement factor H
CHAT choline O-acetyltransferase
CNGB3 cyclic nucleotide gated channel beta 3
CNTFR ciliary neurotrophic factor receptor
COL17A1 collagen, type XVII, alpha 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCHS2 dachsous cadherin-related 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOCK9 dedicator of cytokinesis 9
DUSP1 dual specificity phosphatase 1
EGFL7 EGF-like-domain, multiple 7
ESR1 estrogen receptor 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FHL3 four and a half LIM domains 3
FKBP5 FK506 binding protein 5
GAL galanin/GMAP prepropeptide
GAS1 growth arrest-specific 1
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GGT1 gamma-glutamyltransferase 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRM8 glutamate receptor, metabotropic 8
GSTM5 glutathione S-transferase mu 5
HR hair growth associated
IDS iduronate 2-sulfatase
ING4 inhibitor of growth family, member 4
JAK3 Janus kinase 3
KIF1C kinesin family member 1C
KLF13 Kruppel-like factor 13
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
KPNA5 karyopherin alpha 5 (importin alpha 6)
LCAT lecithin-cholesterol acyltransferase
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK14 mitogen-activated protein kinase 14
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MON2 MON2 homolog (S. cerevisiae)
MT1H metallothionein 1H
MYOZ3 myozenin 3
NEK9 NIMA-related kinase 9
NNMT nicotinamide N-methyltransferase
NUMA1 nuclear mitotic apparatus protein 1
OBSL1 obscurin-like 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PAPPA2 pappalysin 2
PAWR PRKC, apoptosis, WT1, regulator
PER1 period circadian clock 1
PEX3 peroxisomal biogenesis factor 3
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLAT plasminogen activator, tissue
PLCG1 phospholipase C, gamma 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSG6 pregnancy specific beta-1-glycoprotein 6
PTN pleiotrophin
RAB6B RAB6B, member RAS oncogene family
RUNX1 runt-related transcription factor 1
SAPCD1 suppressor APC domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SHOX2 short stature homeobox 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPG20 spastic paraplegia 20 (Troyer syndrome)
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TACC1 transforming, acidic coiled-coil containing protein 1
TADA3 transcriptional adaptor 3
TEF thyrotrophic embryonic factor
TLDC1 TBC/LysM-associated domain containing 1
TLR2 toll-like receptor 2
TNS4 tensin 4
TNXB tenascin XB
ZER1 zyg-11 related, cell cycle regulator
ZIM2 zinc finger, imprinted 2
ZNF287 zinc finger protein 287
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADGRB2 adhesion G protein-coupled receptor B2
ADGRL2 adhesion G protein-coupled receptor L2
BCHE butyrylcholinesterase
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
C8ORF44 chromosome 8 open reading frame 44
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC134 coiled-coil domain containing 134
CCDC186 coiled-coil domain containing 186
CD3D CD3d molecule, delta (CD3-TCR complex)
CD53 CD53 molecule
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
CLDN11 claudin 11
CLDN15 claudin 15
CPZ carboxypeptidase Z
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DTX2 deltex 2, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
ERCC4 excision repair cross-complementation group 4
FOXO4 forkhead box O4
GAL3ST4 galactose-3-O-sulfotransferase 4
GAN gigaxonin
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GIF gastric intrinsic factor (vitamin B synthesis)
GPR21 G protein-coupled receptor 21
GREB1L growth regulation by estrogen in breast cancer-like
GUSBP3 glucuronidase, beta pseudogene 3
HHAT hedgehog acyltransferase
HIST1H2AB histone cluster 1, H2ab
HIST1H2AL histone cluster 1, H2al
IHH indian hedgehog
IL33 interleukin 33
INO80D INO80 complex subunit D
ITGA10 integrin, alpha 10
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIAA0513 KIAA0513
LIMD2 LIM domain containing 2
LOC100131532 uncharacterized LOC100131532
LPAR6 lysophosphatidic acid receptor 6
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC2 leucine rich repeat containing 2
LRRC37A3 leucine rich repeat containing 37, member A3
LRRK1 leucine-rich repeat kinase 1
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MBTD1 mbt domain containing 1
MMP9 matrix metallopeptidase 9
MMRN2 multimerin 2
MRPL41 mitochondrial ribosomal protein L41
NAT6 N-acetyltransferase 6 (GCN5-related)
NGF nerve growth factor (beta polypeptide)
NPY1R neuropeptide Y receptor Y1
NTNG1 netrin G1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PCDHGB5 protocadherin gamma subfamily B, 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP prolactin-induced protein
PLA2G1B phospholipase A2, group IB (pancreas)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RNF39 ring finger protein 39
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
STXBP5L syntaxin binding protein 5-like
SUSD4 sushi domain containing 4
TCEAL2 transcription elongation factor A (SII)-like 2
TENM4 teneurin transmembrane protein 4
TEP1 telomerase-associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM206 transmembrane protein 206
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAC T cell receptor alpha constant
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN2 tetraspanin 2
USP27X ubiquitin specific peptidase 27, X-linked
VASP vasodilator-stimulated phosphoprotein
VGLL3 vestigial-like family member 3
WNT16 wingless-type MMTV integration site family, member 16
WT1-AS WT1 antisense RNA
XYLT2 xylosyltransferase II
ZBTB33 zinc finger and BTB domain containing 33
ZFHX2 zinc finger homeobox 2
ZNF639 zinc finger protein 639
ZNF721 zinc finger protein 721