flavoxate-7405 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the flavoxate-7405 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AGFG2 ArfGAP with FG repeats 2
ARL4C ADP-ribosylation factor-like 4C
ATP10A ATPase, class V, type 10A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BGLAP bone gamma-carboxyglutamate (gla) protein
BIN1 bridging integrator 1
CBX7 chromobox homolog 7
CD248 CD248 molecule, endosialin
CEP250 centrosomal protein 250kDa
CLCA1 chloride channel accessory 1
CLCN7 chloride channel, voltage-sensitive 7
CLUAP1 clusterin associated protein 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAGLA diacylglycerol lipase, alpha
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EGFL7 EGF-like-domain, multiple 7
EPHB3 EPH receptor B3
EPHB6 EPH receptor B6
EPN2 epsin 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXL7 F-box and leucine-rich repeat protein 7
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGD1 FYVE, RhoGEF and PH domain containing 1
FLT4 fms-related tyrosine kinase 4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR157 G protein-coupled receptor 157
GPR85 G protein-coupled receptor 85
GSK3A glycogen synthase kinase 3 alpha
GYPB glycophorin B (MNS blood group)
HCFC1 host cell factor C1
HIST1H2BJ histone cluster 1, H2bj
HIST1H3E histone cluster 1, H3e
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICOSLG inducible T-cell co-stimulator ligand
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFT140 intraflagellar transport 140
IL22 interleukin 22
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KLHL28 kelch-like family member 28
LIN7A lin-7 homolog A (C. elegans)
LOC730101 uncharacterized LOC730101
MAN2C1 mannosidase, alpha, class 2C, member 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD1 methyl-CpG binding domain protein 1
MYL10 myosin, light chain 10, regulatory
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP16 NOP16 nucleolar protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR1A1 olfactory receptor, family 1, subfamily A, member 1
PALM paralemmin
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRSS16 protease, serine, 16 (thymus)
PSD4 pleckstrin and Sec7 domain containing 4
PSG6 pregnancy specific beta-1-glycoprotein 6
PXDC1 PX domain containing 1
RAB3A RAB3A, member RAS oncogene family
RANBP1 RAN binding protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RND1 Rho family GTPase 1
RUNX2 runt-related transcription factor 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGSM2 small G protein signaling modulator 2
SH2D3A SH2 domain containing 3A
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMG7-AS1 SMG7 antisense RNA 1
SOCS1 suppressor of cytokine signaling 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR2B small proline-rich protein 2B
SRCAP Snf2-related CREBBP activator protein
SSPN sarcospan
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBC1D2 TBC1 domain family, member 2
TEX15 testis expressed 15
TMC5 transmembrane channel-like 5
TMEM120B transmembrane protein 120B
TP53I11 tumor protein p53 inducible protein 11
ULK2 unc-51 like autophagy activating kinase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
UTRN utrophin
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YTHDC2 YTH domain containing 2
ZNF362 zinc finger protein 362
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
AMPD2 adenosine monophosphate deaminase 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASB13 ankyrin repeat and SOCS box containing 13
ATAD3A ATPase family, AAA domain containing 3A
BAX BCL2-associated X protein
BLMH bleomycin hydrolase
BRIX1 BRX1, biogenesis of ribosomes
C10ORF88 chromosome 10 open reading frame 88
C5ORF28 chromosome 5 open reading frame 28
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CCND1 cyclin D1
CISH cytokine inducible SH2-containing protein
CXCL12 chemokine (C-X-C motif) ligand 12
DTWD1 DTW domain containing 1
E2F6 E2F transcription factor 6
EGR3 early growth response 3
FAM216A family with sequence similarity 216, member A
FBRS fibrosin
FHL2 four and a half LIM domains 2
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
FZD4 frizzled class receptor 4
GAB2 GRB2-associated binding protein 2
GNL1 guanine nucleotide binding protein-like 1
GPR19 G protein-coupled receptor 19
HIRA histone cell cycle regulator
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
ING3 inhibitor of growth family, member 3
INSIG2 insulin induced gene 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA0125 KIAA0125
KRI1 KRI1 homolog (S. cerevisiae)
LRRC37A2 leucine rich repeat containing 37, member A2
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD11 major facilitator superfamily domain containing 11
MLYCD malonyl-CoA decarboxylase
MORC3 MORC family CW-type zinc finger 3
MREG melanoregulin
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NMRK1 nicotinamide riboside kinase 1
NMU neuromedin U
NOL6 nucleolar protein 6 (RNA-associated)
NPY1R neuropeptide Y receptor Y1
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PC pyruvate carboxylase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCYOX1L prenylcysteine oxidase 1 like
PDZK1 PDZ domain containing 1
PEX26 peroxisomal biogenesis factor 26
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PROCR protein C receptor, endothelial
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD51AP1 RAD51 associated protein 1
RAI14 retinoic acid induced 14
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCL1 RNA terminal phosphate cyclase-like 1
RCOR3 REST corepressor 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS19 regulator of G-protein signaling 19
RHOBTB1 Rho-related BTB domain containing 1
RNF123 ring finger protein 123
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRP1 ribosomal RNA processing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SHPK sedoheptulokinase
SIAH2 siah E3 ubiquitin protein ligase 2
SIK1 salt-inducible kinase 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNIP1 Smad nuclear interacting protein 1
STC2 stanniocalcin 2
STYXL1 serine/threonine/tyrosine interacting-like 1
SUSD4 sushi domain containing 4
TMEM164 transmembrane protein 164
TPST2 tyrosylprotein sulfotransferase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
TUBGCP5 tubulin, gamma complex associated protein 5
USP18 ubiquitin specific peptidase 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF239 zinc finger protein 239