flavoxate-6326 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the flavoxate-6326 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
AKAP7 A kinase (PRKA) anchor protein 7
ANAPC5 anaphase promoting complex subunit 5
ANKLE2 ankyrin repeat and LEM domain containing 2
ANXA10 annexin A10
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
ARHGAP1 Rho GTPase activating protein 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BATF basic leucine zipper transcription factor, ATF-like
BCAP29 B-cell receptor-associated protein 29
BMP3 bone morphogenetic protein 3
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
CAV2 caveolin 2
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIB2 calcium and integrin binding family member 2
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYB5R2 cytochrome b5 reductase 2
CYLD cylindromatosis (turban tumor syndrome)
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFNB31 deafness, autosomal recessive 31
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMP1 epithelial membrane protein 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHX2 epoxide hydrolase 2, cytoplasmic
ESRRG estrogen-related receptor gamma
ETV5 ets variant 5
FAM13A family with sequence similarity 13, member A
FBN1 fibrillin 1
GBP1 guanylate binding protein 1, interferon-inducible
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPC1 glypican 1
HIST1H4D histone cluster 1, H4d
HOXC10 homeobox C10
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNIP1 Kv channel interacting protein 1
KDM4C lysine (K)-specific demethylase 4C
LOC257152 uncharacterized LOC257152
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K7 mitogen-activated protein kinase kinase 7
MB myoglobin
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTAP methylthioadenosine phosphorylase
MTMR3 myotubularin related protein 3
MXD4 MAX dimerization protein 4
MYO15A myosin XVA
MYOF myoferlin
MYOZ1 myozenin 1
NAAA N-acylethanolamine acid amidase
NEK11 NIMA-related kinase 11
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL2 NIPA-like domain containing 2
NOX1 NADPH oxidase 1
NRXN3 neurexin 3
PARD6A par-6 family cell polarity regulator alpha
PCOLCE procollagen C-endopeptidase enhancer
PDCD2 programmed cell death 2
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA1 plexin A1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGS14 regulator of G-protein signaling 14
SAFB scaffold attachment factor B
SCARB1 scavenger receptor class B, member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMO smoothened, frizzled class receptor
SPRYD7 SPRY domain containing 7
SSX3 synovial sarcoma, X breakpoint 3
SYNJ2 synaptojanin 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAPBP TAP binding protein (tapasin)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBL1Y transducin (beta)-like 1, Y-linked
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFCP2L1 transcription factor CP2-like 1
TGFB2 transforming growth factor, beta 2
THBD thrombomodulin
TLDC1 TBC/LysM-associated domain containing 1
TUBA3C tubulin, alpha 3c
VGF VGF nerve growth factor inducible
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF174 zinc finger protein 174
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
AES amino-terminal enhancer of split
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BDNF brain-derived neurotrophic factor
BEX1 brain expressed, X-linked 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C19ORF54 chromosome 19 open reading frame 54
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CCDC47 coiled-coil domain containing 47
CCDC94 coiled-coil domain containing 94
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNN2 calponin 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CST6 cystatin E/M
DCAF16 DDB1 and CUL4 associated factor 16
DCLRE1A DNA cross-link repair 1A
DEAF1 DEAF1 transcription factor
EFNA1 ephrin-A1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERF Ets2 repressor factor
EVPL envoplakin
FAM131A family with sequence similarity 131, member A
FAM134C family with sequence similarity 134, member C
FAM222B family with sequence similarity 222, member B
FBXL6 F-box and leucine-rich repeat protein 6
GCHFR GTP cyclohydrolase I feedback regulator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL1 guanine nucleotide binding protein-like 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HPS6 Hermansky-Pudlak syndrome 6
HYAL3 hyaluronoglucosaminidase 3
IFITM1 interferon induced transmembrane protein 1
IL17RA interleukin 17 receptor A
JUNB jun B proto-oncogene
KIAA0556 KIAA0556
KRI1 KRI1 homolog (S. cerevisiae)
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAPK12 mitogen-activated protein kinase 12
MOSPD3 motile sperm domain containing 3
MRPL41 mitochondrial ribosomal protein L41
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOL12 nucleolar protein 12
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NXPE3 neurexophilin and PC-esterase domain family, member 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDIA3 protein disulfide isomerase family A, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PKN1 protein kinase N1
PLAC1 placenta-specific 1
POMT2 protein-O-mannosyltransferase 2
PTGFR prostaglandin F receptor (FP)
RABL6 RAB, member RAS oncogene family-like 6
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC25A40 solute carrier family 25, member 40
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNIP1 Smad nuclear interacting protein 1
SOX12 SRY (sex determining region Y)-box 12
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEAD4 TEA domain family member 4
TGIF1 TGFB-induced factor homeobox 1
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H12A zinc finger CCCH-type containing 12A
ZNF204P zinc finger protein 204, pseudogene
ZNF767P zinc finger family member 767, pseudogene
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2