finasteride-4766 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the finasteride-4766 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACOT11 acyl-CoA thioesterase 11
ADAM22 ADAM metallopeptidase domain 22
ADCK4 aarF domain containing kinase 4
AHNAK2 AHNAK nucleoprotein 2
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGAP24 Rho GTPase activating protein 24
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BCL2A1 BCL2-related protein A1
BIRC7 baculoviral IAP repeat containing 7
BMP8A bone morphogenetic protein 8a
C11ORF1 chromosome 11 open reading frame 1
C1ORF54 chromosome 1 open reading frame 54
C5AR1 complement component 5a receptor 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CDK13 cyclin-dependent kinase 13
CEP135 centrosomal protein 135kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CPNE7 copine VII
CTNS cystinosin, lysosomal cystine transporter
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP6 dual specificity phosphatase 6
EHBP1L1 EH domain binding protein 1-like 1
EMCN endomucin
FGD1 FYVE, RhoGEF and PH domain containing 1
FRMD8 FERM domain containing 8
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRPR gastrin-releasing peptide receptor
GSN gelsolin
HIPK3 homeodomain interacting protein kinase 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HRH1 histamine receptor H1
ICA1 islet cell autoantigen 1, 69kDa
IFI16 interferon, gamma-inducible protein 16
IGHMBP2 immunoglobulin mu binding protein 2
IL11 interleukin 11
IL2RG interleukin 2 receptor, gamma
IQCC IQ motif containing C
ITGB6 integrin, beta 6
LAMB4 laminin, beta 4
LOC100127972 uncharacterized LOC100127972
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MECOM MDS1 and EVI1 complex locus
MMP11 matrix metallopeptidase 11
MORN1 MORN repeat containing 1
MRPL41 mitochondrial ribosomal protein L41
MVB12B multivesicular body subunit 12B
MX1 MX dynamin-like GTPase 1
NCKIPSD NCK interacting protein with SH3 domain
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGDN neuroguidin, EIF4E binding protein
NKX3-1 NK3 homeobox 1
NRXN3 neurexin 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAPPA2 pappalysin 2
PCDHB11 protocadherin beta 11
PCDHGA10 protocadherin gamma subfamily A, 10
PCSK6 proprotein convertase subtilisin/kexin type 6
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PITX2 paired-like homeodomain 2
PKN2 protein kinase N2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
POM121L2 POM121 transmembrane nucleoporin-like 2
POU5F1B POU class 5 homeobox 1B
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PSG3 pregnancy specific beta-1-glycoprotein 3
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM48 RNA binding motif protein 48
RBMS2 RNA binding motif, single stranded interacting protein 2
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RUNDC3A RUN domain containing 3A
SATB2 SATB homeobox 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SIX2 SIX homeobox 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
STAB2 stabilin 2
SYNC syncoilin, intermediate filament protein
TBRG4 transforming growth factor beta regulator 4
THRB thyroid hormone receptor, beta
TM4SF4 transmembrane 4 L six family member 4
TMEM45A transmembrane protein 45A
TMEM63A transmembrane protein 63A
TMPRSS4 transmembrane protease, serine 4
TSC22D4 TSC22 domain family, member 4
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACBD4 acyl-CoA binding domain containing 4
ADAM2 ADAM metallopeptidase domain 2
ADGRE5 adhesion G protein-coupled receptor E5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APOLD1 apolipoprotein L domain containing 1
C14ORF79 chromosome 14 open reading frame 79
CA11 carbonic anhydrase XI
CAPN15 calpain 15
CD83 CD83 molecule
CLEC7A C-type lectin domain family 7, member A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNN1 calponin 1, basic, smooth muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRY2 cryptochrome circadian clock 2
CXCR2 chemokine (C-X-C motif) receptor 2
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM3 dynamin 3
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FER fer (fps/fes related) tyrosine kinase
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
GAMT guanidinoacetate N-methyltransferase
GEM GTP binding protein overexpressed in skeletal muscle
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR143 G protein-coupled receptor 143
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HOXA7 homeobox A7
HPN hepsin
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
INPP1 inositol polyphosphate-1-phosphatase
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA0754 KIAA0754
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP9 microtubule-associated protein 9
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM4 MDM4, p53 regulator
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMRN2 multimerin 2
MOSPD3 motile sperm domain containing 3
MTCP1 mature T-cell proliferation 1
MXD3 MAX dimerization protein 3
NOTCH4 notch 4
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
ONECUT1 one cut homeobox 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAX9 paired box 9
PEX26 peroxisomal biogenesis factor 26
PGR progesterone receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAT plasminogen activator, tissue
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
POU4F2 POU class 4 homeobox 2
PRF1 perforin 1 (pore forming protein)
PTDSS2 phosphatidylserine synthase 2
R3HCC1L R3H domain and coiled-coil containing 1-like
SAYSD1 SAYSVFN motif domain containing 1
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SPAG7 sperm associated antigen 7
SPINK1 serine peptidase inhibitor, Kazal type 1
STEAP4 STEAP family member 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TNNI3 troponin I type 3 (cardiac)
TPST1 tyrosylprotein sulfotransferase 1
TPST2 tyrosylprotein sulfotransferase 2
UCN urocortin
USP19 ubiquitin specific peptidase 19
VIPR1 vasoactive intestinal peptide receptor 1
YOD1 YOD1 deubiquitinase
ZBTB22 zinc finger and BTB domain containing 22
ZFHX4 zinc finger homeobox 4
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF423 zinc finger protein 423
ZNF506 zinc finger protein 506
ZNF750 zinc finger protein 750