fibrous tissue neoplasm Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A connective tissue cancer that has_material_basis_in fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern. (Human Disease Ontology, DOID_3355)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0012316
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Genes

32 genes associated with the fibrous tissue neoplasm phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANTXR2 anthrax toxin receptor 2
APC adenomatous polyposis coli
CREB1 cAMP responsive element binding protein 1
DHCR24 24-dehydrocholesterol reductase
FLNA filamin A, alpha
HRAS Harvey rat sarcoma viral oncogene homolog
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLLN killin, p53-regulated DNA replication inhibitor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
MEN1 multiple endocrine neoplasia I
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCD1 phospholipase C, delta 1
PTCH1 patched 1
PTCH2 patched 2
PTEN phosphatase and tensin homolog
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SOS1 son of sevenless homolog 1 (Drosophila)
SPRED1 sprouty-related, EVH1 domain containing 1
SUFU suppressor of fused homolog (Drosophila)
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2