fibroblast Gene Set

Dataset TISSUES Curated Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000452)
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Genes

254 proteins highly expressed in the tissue fibroblast from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABR active BCR-related
ACAD8 acyl-CoA dehydrogenase family, member 8
ADAP1 ArfGAP with dual PH domains 1
ADI1 acireductone dioxygenase 1
AJAP1 adherens junctions associated protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ALDOA aldolase A, fructose-bisphosphate
ANXA7 annexin A7
AP3M1 adaptor-related protein complex 3, mu 1 subunit
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGAP1 Rho GTPase activating protein 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AXL AXL receptor tyrosine kinase
BIN1 bridging integrator 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C1QBP complement component 1, q subcomponent binding protein
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALD1 caldesmon 1
CANT1 calcium activated nucleotidase 1
CANX calnexin
CAT catalase
CC2D1A coiled-coil and C2 domain containing 1A
CCDC130 coiled-coil domain containing 130
CCDC6 coiled-coil domain containing 6
CCKBR cholecystokinin B receptor
CCL13 chemokine (C-C motif) ligand 13
CCNG1 cyclin G1
CDC123 cell division cycle 123
CDK7 cyclin-dependent kinase 7
CFLAR CASP8 and FADD-like apoptosis regulator
CHMP1A charged multivesicular body protein 1A
CHN1 chimerin 1
COL16A1 collagen, type XVI, alpha 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CRELD1 cysteine-rich with EGF-like domains 1
CRY1 cryptochrome circadian clock 1
CXCL12 chemokine (C-X-C motif) ligand 12
DUT deoxyuridine triphosphatase
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5A eukaryotic translation initiation factor 5A
ELN elastin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
F5 coagulation factor V (proaccelerin, labile factor)
FAIM2 Fas apoptotic inhibitory molecule 2
FAP fibroblast activation protein, alpha
FBLN2 fibulin 2
FBN1 fibrillin 1
FERMT2 fermitin family member 2
FGFR1 fibroblast growth factor receptor 1
FLNC filamin C, gamma
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GAK cyclin G associated kinase
GALC galactosylceramidase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALT galactose-1-phosphate uridylyltransferase
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GLA galactosidase, alpha
GLTP glycolipid transfer protein
GOLGA5 golgin A5
GOLT1B golgi transport 1B
GPC1 glypican 1
GPR162 G protein-coupled receptor 162
GPR89A G protein-coupled receptor 89A
GPR89B G protein-coupled receptor 89B
GTF2H5 general transcription factor IIH, polypeptide 5
GUSB glucuronidase, beta
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HDAC3 histone deacetylase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HESX1 HESX homeobox 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGA2 high mobility group AT-hook 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HPSE heparanase
HR hair growth associated
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPG2 heparan sulfate proteoglycan 2
IDO1 indoleamine 2,3-dioxygenase 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGFBP6 insulin-like growth factor binding protein 6
IL20RA interleukin 20 receptor, alpha
IL24 interleukin 24
IL6 interleukin 6
INSR insulin receptor
ITGA11 integrin, alpha 11
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KAT5 K(lysine) acetyltransferase 5
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM2B lysine (K)-specific demethylase 2B
KDM5C lysine (K)-specific demethylase 5C
KLC3 kinesin light chain 3
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LAMC2 laminin, gamma 2
LAMP2 lysosomal-associated membrane protein 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOXL1 lysyl oxidase-like 1
LRRC8A leucine rich repeat containing 8 family, member A
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LY6K lymphocyte antigen 6 complex, locus K
MAP1B microtubule-associated protein 1B
MAVS mitochondrial antiviral signaling protein
MBD1 methyl-CpG binding domain protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFAP3 microfibrillar-associated protein 3
MIB2 mindbomb E3 ubiquitin protein ligase 2
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOXD1 monooxygenase, DBH-like 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NADK NAD kinase
NBN nibrin
NDFIP1 Nedd4 family interacting protein 1
NDFIP2 Nedd4 family interacting protein 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEK9 NIMA-related kinase 9
NEU1 sialidase 1 (lysosomal sialidase)
NEU4 sialidase 4
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OAZ1 ornithine decarboxylase antizyme 1
PAN3 PAN3 poly(A) specific ribonuclease subunit
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PCCB propionyl CoA carboxylase, beta polypeptide
PCM1 pericentriolar material 1
PEX26 peroxisomal biogenesis factor 26
PFDN5 prefoldin subunit 5
PHF5A PHD finger protein 5A
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMP22 peripheral myelin protein 22
PPA2 pyrophosphatase (inorganic) 2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRRX2 paired related homeobox 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTK7 protein tyrosine kinase 7 (inactive)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYCARD PYD and CARD domain containing
RAD17 RAD17 homolog (S. pombe)
RAN RAN, member RAS oncogene family
RBMS3 RNA binding motif, single stranded interacting protein 3
RCAN2 regulator of calcineurin 2
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RET ret proto-oncogene
RPL11 ribosomal protein L11
RPL26 ribosomal protein L26
RPL7 ribosomal protein L7
RTN4 reticulon 4
S100A6 S100 calcium binding protein A6
SCFD1 sec1 family domain containing 1
SDC1 syndecan 1
SDC2 syndecan 2
SDC4 syndecan 4
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFRP1 secreted frizzled-related protein 1
SH3BP4 SH3-domain binding protein 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHOX2 short stature homeobox 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPN small nuclear ribonucleoprotein polypeptide N
SSX1 synovial sarcoma, X breakpoint 1
SSX3 synovial sarcoma, X breakpoint 3
ST7 suppression of tumorigenicity 7
STC1 stanniocalcin 1
SUMO1 small ubiquitin-like modifier 1
TAGLN transgelin
TBP TATA box binding protein
TCF4 transcription factor 4
TDGF1 teratocarcinoma-derived growth factor 1
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TIPRL TOR signaling pathway regulator
TMED4 transmembrane emp24 protein transport domain containing 4
TMEM184B transmembrane protein 184B
TMEM189 transmembrane protein 189
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM241 transmembrane protein 241
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4
TRIO trio Rho guanine nucleotide exchange factor
TRIP11 thyroid hormone receptor interactor 11
TUBB tubulin, beta class I
TUBB4B tubulin, beta 4B class IVb
TWF1 twinfilin actin binding protein 1
UCK2 uridine-cytidine kinase 2
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
VCAN versican
VEGFB vascular endothelial growth factor B
VIM vimentin
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
XPA xeroderma pigmentosum, complementation group A
ZBTB7B zinc finger and BTB domain containing 7B
ZDHHC13 zinc finger, DHHC-type containing 13
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF75D zinc finger protein 75D