fenoprofen-4736 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the fenoprofen-4736 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASIC1 acid sensing (proton gated) ion channel 1
BDKRB2 bradykinin receptor B2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTN3A3 butyrophilin, subfamily 3, member A3
C9ORF9 chromosome 9 open reading frame 9
CCDC134 coiled-coil domain containing 134
CD52 CD52 molecule
CD6 CD6 molecule
CDH8 cadherin 8, type 2
COL1A1 collagen, type I, alpha 1
COL8A1 collagen, type VIII, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CSHL1 chorionic somatomammotropin hormone-like 1
CYBB cytochrome b-245, beta polypeptide
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DPYS dihydropyrimidinase
DTX2 deltex 2, E3 ubiquitin ligase
EFR3B EFR3 homolog B (S. cerevisiae)
EGR4 early growth response 4
ERC2-IT1 ERC2 intronic transcript 1
FAM186A family with sequence similarity 186, member A
FBXO2 F-box protein 2
FBXO21 F-box protein 21
FBXO40 F-box protein 40
FSCN1 fascin actin-bundling protein 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GFI1 growth factor independent 1 transcription repressor
GIMAP6 GTPase, IMAP family member 6
GJA4 gap junction protein, alpha 4, 37kDa
GPR3 G protein-coupled receptor 3
GPR68 G protein-coupled receptor 68
GRM8 glutamate receptor, metabotropic 8
HOXD10 homeobox D10
ICAM1 intercellular adhesion molecule 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNA1 interferon, alpha 1
IL18 interleukin 18
INSR insulin receptor
ITGA8 integrin, alpha 8
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF9 Kruppel-like factor 9
KYNU kynureninase
LAT2 linker for activation of T cells family, member 2
LEFTY1 left-right determination factor 1
LIME1 Lck interacting transmembrane adaptor 1
LOC440895 two pore channel 3 pseudogene
LPAR4 lysophosphatidic acid receptor 4
MAB21L1 mab-21-like 1 (C. elegans)
MAPK7 mitogen-activated protein kinase 7
METTL7A methyltransferase like 7A
MGAM maltase-glucoamylase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MR1 major histocompatibility complex, class I-related
MTMR7 myotubularin related protein 7
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPY neuropeptide Y
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OCA2 oculocutaneous albinism II
PADI4 peptidyl arginine deiminase, type IV
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRB3 proline-rich protein BstNI subfamily 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPRM protein tyrosine phosphatase, receptor type, M
RAB40A RAB40A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS12 regulator of G-protein signaling 12
SERHL2 serine hydrolase-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIRPA signal-regulatory protein alpha
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPK3 SRSF protein kinase 3
SSX1 synovial sarcoma, X breakpoint 1
SSX3 synovial sarcoma, X breakpoint 3
SYNPO synaptopodin
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCF12 transcription factor 12
TDRD12 tudor domain containing 12
THOC5 THO complex 5
TMPRSS4 transmembrane protease, serine 4
TSC22D4 TSC22 domain family, member 4
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
XYLB xylulokinase homolog (H. influenzae)
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARMC6 armadillo repeat containing 6
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC6 coiled-coil domain containing 6
CD82 CD82 molecule
CLCN6 chloride channel, voltage-sensitive 6
COCH cochlin
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4B DBF4 zinc finger B
DGAT1 diacylglycerol O-acyltransferase 1
DOCK4 dedicator of cytokinesis 4
DYSF dysferlin
ECH1 enoyl CoA hydratase 1, peroxisomal
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM110B family with sequence similarity 110, member B
FAM131A family with sequence similarity 131, member A
FKBP5 FK506 binding protein 5
FNTB farnesyltransferase, CAAX box, beta
FRS2 fibroblast growth factor receptor substrate 2
GBP2 guanylate binding protein 2, interferon-inducible
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH2L G patch domain containing 2-like
GPR157 G protein-coupled receptor 157
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
INPP5J inositol polyphosphate-5-phosphatase J
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIN7A lin-7 homolog A (C. elegans)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRPL44 mitochondrial ribosomal protein L44
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PARD6A par-6 family cell polarity regulator alpha
PCDHA6 protocadherin alpha 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMCH pro-melanin-concentrating hormone
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSENEN presenilin enhancer gamma secretase subunit
PSKH1 protein serine kinase H1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM23 RNA binding motif protein 23
RNF208 ring finger protein 208
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCRN3 secernin 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STIM1 stromal interaction molecule 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM242 transmembrane protein 242
TMPRSS3 transmembrane protease, serine 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
VASH2 vasohibin 2
ZNF205 zinc finger protein 205
ZNF423 zinc finger protein 423
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF606 zinc finger protein 606
ZNF804A zinc finger protein 804A