fenoprofen-4274 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the fenoprofen-4274 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ARHGAP33 Rho GTPase activating protein 33
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASTN1 astrotactin 1
ATAT1 alpha tubulin acetyltransferase 1
ATN1 atrophin 1
BAIAP3 BAI1-associated protein 3
C14ORF1 chromosome 14 open reading frame 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD6 CD6 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDRT1 CMT1A duplicated region transcript 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CLDN8 claudin 8
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL6A1 collagen, type VI, alpha 1
CRP C-reactive protein, pentraxin-related
CST4 cystatin S
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DGCR2 DiGeorge syndrome critical region gene 2
DOK4 docking protein 4
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FBXO40 F-box protein 40
FBXO41 F-box protein 41
FGFR1 fibroblast growth factor receptor 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GFER growth factor, augmenter of liver regeneration
GGT1 gamma-glutamyltransferase 1
GGTLC1 gamma-glutamyltransferase light chain 1
GPNMB glycoprotein (transmembrane) nmb
GPR15 G protein-coupled receptor 15
H2AFX H2A histone family, member X
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HMGA1 high mobility group AT-hook 1
HOXA6 homeobox A6
HSF1 heat shock transcription factor 1
HSPG2 heparan sulfate proteoglycan 2
IL32 interleukin 32
IQCK IQ motif containing K
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF4 interferon regulatory factor 4
KIF22 kinesin family member 22
KLK7 kallikrein-related peptidase 7
LAD1 ladinin 1
LINC00312 long intergenic non-protein coding RNA 312
LRP1 low density lipoprotein receptor-related protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD2 methyl-CpG binding domain protein 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCF2L MCF.2 cell line derived transforming sequence-like
MEF2D myocyte enhancer factor 2D
MEGF8 multiple EGF-like-domains 8
MINK1 misshapen-like kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MVB12B multivesicular body subunit 12B
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NUCB1 nucleobindin 1
OSBP2 oxysterol binding protein 2
PAX2 paired box 2
PAX8 paired box 8
PBX1 pre-B-cell leukemia homeobox 1
PCDHA5 protocadherin alpha 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP3 plakophilin 3
PMFBP1 polyamine modulated factor 1 binding protein 1
PRB1 proline-rich protein BstNI subfamily 1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTMS parathymosin
PXN paxillin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL23AP53 ribosomal protein L23a pseudogene 53
RRAGD Ras-related GTP binding D
SBNO2 strawberry notch homolog 2 (Drosophila)
SH3D21 SH3 domain containing 21
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SORBS3 sorbin and SH3 domain containing 3
TAL1 T-cell acute lymphocytic leukemia 1
TAPT1 transmembrane anterior posterior transformation 1
TFEC transcription factor EC
TLN1 talin 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRA T cell receptor alpha locus
TRIM25 tripartite motif containing 25
TRIM3 tripartite motif containing 3
TRIM49 tripartite motif containing 49
TTLL1 tubulin tyrosine ligase-like family member 1
WNT3 wingless-type MMTV integration site family, member 3
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZFHX3 zinc finger homeobox 3
ZIM2 zinc finger, imprinted 2
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD3 abhydrolase domain containing 3
AGO4 argonaute RISC catalytic component 4
AP1AR adaptor-related protein complex 1 associated regulatory protein
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGAP24 Rho GTPase activating protein 24
BICD1 bicaudal D homolog 1 (Drosophila)
CXCL6 chemokine (C-X-C motif) ligand 6
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND5B DENN/MADD domain containing 5B
DEPDC1 DEP domain containing 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERAP2 endoplasmic reticulum aminopeptidase 2
ETNK2 ethanolamine kinase 2
FAIM Fas apoptotic inhibitory molecule
FAM169A family with sequence similarity 169, member A
FAM204A family with sequence similarity 204, member A
FBXL4 F-box and leucine-rich repeat protein 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAR1 GAR1 ribonucleoprotein
GAS8 growth arrest-specific 8
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLDC glycine dehydrogenase (decarboxylating)
GPALPP1 GPALPP motifs containing 1
GPATCH2L G patch domain containing 2-like
GPR1 G protein-coupled receptor 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4C histone cluster 1, H4c
IER3IP1 immediate early response 3 interacting protein 1
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT81 intraflagellar transport 81
IL33 interleukin 33
KLHL36 kelch-like family member 36
KRBOX4 KRAB box domain containing 4
LYPLA1 lysophospholipase I
MAGEA6 melanoma antigen family A6
MAGOHB mago-nashi homolog B (Drosophila)
MANEA mannosidase, endo-alpha
METTL16 methyltransferase like 16
MGC12488
MIS12 MIS12 kinetochore complex component
MIS18BP1 MIS18 binding protein 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NABP1 nucleic acid binding protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NT5DC3 5'-nucleotidase domain containing 3
PDE12 phosphodiesterase 12
PDZD2 PDZ domain containing 2
PDZK1 PDZ domain containing 1
PHF14 PHD finger protein 14
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTK6 protein tyrosine kinase 6
RBBP5 retinoblastoma binding protein 5
SERINC5 serine incorporator 5
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX10 sorting nexin 10
SNX16 sorting nexin 16
SPATS2 spermatogenesis associated, serine-rich 2
SPIDR scaffolding protein involved in DNA repair
STIL SCL/TAL1 interrupting locus
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THAP1 THAP domain containing, apoptosis associated protein 1
TM6SF1 transmembrane 6 superfamily member 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM209 transmembrane protein 209
TMSB15A thymosin beta 15a
TWISTNB TWIST neighbor
USP36 ubiquitin specific peptidase 36
WDR25 WD repeat domain 25
WDR43 WD repeat domain 43
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB3 zinc finger and BTB domain containing 3
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF215 zinc finger protein 215
ZNF529 zinc finger protein 529
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652