fenofibrate-7474 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the fenofibrate-7474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANKRD26 ankyrin repeat domain 26
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
ATF7IP activating transcription factor 7 interacting protein
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CAPN9 calpain 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK13 cyclin-dependent kinase 13
CFLAR CASP8 and FADD-like apoptosis regulator
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CST6 cystatin E/M
CXCR4 chemokine (C-X-C motif) receptor 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DESI2 desumoylating isopeptidase 2
DLC1 DLC1 Rho GTPase activating protein
DLG5 discs, large homolog 5 (Drosophila)
DOK4 docking protein 4
ECM1 extracellular matrix protein 1
EPHA1 EPH receptor A1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM65A family with sequence similarity 65, member A
FGF12 fibroblast growth factor 12
FLOT1 flotillin 1
FOXG1 forkhead box G1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GRPR gastrin-releasing peptide receptor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXB5 homeobox B5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IL9R interleukin 9 receptor
INO80D INO80 complex subunit D
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLHL25 kelch-like family member 25
LENEP lens epithelial protein
LMAN1 lectin, mannose-binding, 1
LY86 lymphocyte antigen 86
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM4 MDM4, p53 regulator
MFSD11 major facilitator superfamily domain containing 11
MID1 midline 1
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MSX2 msh homeobox 2
NKX2-5 NK2 homeobox 5
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
ORC5 origin recognition complex, subunit 5
PAPOLG poly(A) polymerase gamma
PAQR6 progestin and adipoQ receptor family member VI
PHF20 PHD finger protein 20
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PODXL2 podocalyxin-like 2
PROL1 proline rich, lacrimal 1
RAB40C RAB40C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP1 RAN binding protein 1
RARG retinoic acid receptor, gamma
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS12 regulator of G-protein signaling 12
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNFT2 ring finger protein, transmembrane 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SGCE sarcoglycan, epsilon
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A17 solute carrier family 22, member 17
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SOCS7 suppressor of cytokine signaling 7
SRD5A3 steroid 5 alpha-reductase 3
SYMPK symplekin
TADA3 transcriptional adaptor 3
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TM4SF5 transmembrane 4 L six family member 5
TNPO3 transportin 3
TNRC6B trinucleotide repeat containing 6B
TSPAN1 tetraspanin 1
USP34 ubiquitin specific peptidase 34
WNT16 wingless-type MMTV integration site family, member 16
XDH xanthine dehydrogenase
ZBTB17 zinc finger and BTB domain containing 17
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF350 zinc finger protein 350
ZNF609 zinc finger protein 609
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABLIM3 actin binding LIM protein family, member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
BPGM 2,3-bisphosphoglycerate mutase
C16ORF59 chromosome 16 open reading frame 59
CAPRIN2 caprin family member 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPT centromere protein T
CEP85 centrosomal protein 85kDa
CFD complement factor D (adipsin)
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CLEC16A C-type lectin domain family 16, member A
CNGB3 cyclic nucleotide gated channel beta 3
CPTP ceramide-1-phosphate transfer protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKD diacylglycerol kinase, delta 130kDa
DIXDC1 DIX domain containing 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERCC4 excision repair cross-complementation group 4
FAM63A family with sequence similarity 63, member A
FOXD1 forkhead box D1
GAN gigaxonin
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPX2 glutathione peroxidase 2
HDAC11 histone deacetylase 11
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AG histone cluster 1, H2ag
HIST1H2AI histone cluster 1, H2ai
HIST1H4F histone cluster 1, H4f
HPN hepsin
HPS6 Hermansky-Pudlak syndrome 6
HTRA1 HtrA serine peptidase 1
IFT81 intraflagellar transport 81
KLF11 Kruppel-like factor 11
KRT86 keratin 86, type II
LINC00339 long intergenic non-protein coding RNA 339
LMBR1L limb development membrane protein 1-like
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
LZTR1 leucine-zipper-like transcription regulator 1
MAGEH1 melanoma antigen family H1
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL2B methyltransferase like 2B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-2 NK3 homeobox 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5DC3 5'-nucleotidase domain containing 3
ODF2 outer dense fiber of sperm tails 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB3 protocadherin beta 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZD8 PDZ domain containing 8
PHC1 polyhomeotic homolog 1 (Drosophila)
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
QDPR quinoid dihydropteridine reductase
RAB3A RAB3A, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFX7 regulatory factor X, 7
RNF2 ring finger protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
SCHIP1 schwannomin interacting protein 1
SH2B3 SH2B adaptor protein 3
SIDT1 SID1 transmembrane family, member 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TCTN2 tectonic family member 2
TDP1 tyrosyl-DNA phosphodiesterase 1
TMEM184B transmembrane protein 184B
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPST1 tyrosylprotein sulfotransferase 1
TRAF2 TNF receptor-associated factor 2
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VASP vasodilator-stimulated phosphoprotein
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF16 zinc finger protein 16
ZNF324 zinc finger protein 324
ZNF444 zinc finger protein 444
ZNF721 zinc finger protein 721
ZXDC ZXD family zinc finger C