fendiline-7188 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the fendiline-7188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK2 adenylate kinase 2
ARNT aryl hydrocarbon receptor nuclear translocator
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR3 early growth response 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELL2 elongation factor, RNA polymerase II, 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4H histone cluster 1, H4h
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HRK harakiri, BCL2 interacting protein
HSPA13 heat shock protein 70kDa family, member 13
IER2 immediate early response 2
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRF9 interferon regulatory factor 9
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LARP6 La ribonucleoprotein domain family, member 6
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MIR22HG MIR22 host gene
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MVD mevalonate (diphospho) decarboxylase
NBR1 neighbor of BRCA1 gene 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIBF1 progesterone immunomodulatory binding factor 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STYK1 serine/threonine/tyrosine kinase 1
TGIF1 TGFB-induced factor homeobox 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB10 zinc finger and BTB domain containing 10
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD10 abhydrolase domain containing 10
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AKR1C3 aldo-keto reductase family 1, member C3
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
B3GNT1
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCORL1 BCL6 corepressor-like 1
C14ORF132 chromosome 14 open reading frame 132
C22ORF29 chromosome 22 open reading frame 29
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CA2 carbonic anhydrase II
CASKIN2 CASK interacting protein 2
CBR4 carbonyl reductase 4
CCS copper chaperone for superoxide dismutase
CDR2L cerebellar degeneration-related protein 2-like
CHMP6 charged multivesicular body protein 6
CNGB3 cyclic nucleotide gated channel beta 3
DCLRE1A DNA cross-link repair 1A
DEAF1 DEAF1 transcription factor
DSPP dentin sialophosphoprotein
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPN3 epsin 3
FAM114A2 family with sequence similarity 114, member A2
FAM63A family with sequence similarity 63, member A
FBXL14 F-box and leucine-rich repeat protein 14
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUZ fuzzy planar cell polarity protein
FYCO1 FYVE and coiled-coil domain containing 1
GAB2 GRB2-associated binding protein 2
GCHFR GTP cyclohydrolase I feedback regulator
GLI3 GLI family zinc finger 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXC11 homeobox C11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA2 heat shock 70kDa protein 2
IPO8 importin 8
KAT2A K(lysine) acetyltransferase 2A
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0125 KIAA0125
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRRC20 leucine rich repeat containing 20
LYPLA2P1 lysophospholipase II pseudogene 1
MAP6D1 MAP6 domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MMP9 matrix metallopeptidase 9
NARFL nuclear prelamin A recognition factor-like
NCAM2 neural cell adhesion molecule 2
NES nestin
OLFML3 olfactomedin-like 3
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR3 progestin and adipoQ receptor family member III
PARP16 poly (ADP-ribose) polymerase family, member 16
PECR peroxisomal trans-2-enoyl-CoA reductase
PGGT1B protein geranylgeranyltransferase type I, beta subunit
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPT2 palmitoyl-protein thioesterase 2
PRKCD protein kinase C, delta
PYCRL pyrroline-5-carboxylate reductase-like
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL1 retinoblastoma-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RIC8B RIC8 guanine nucleotide exchange factor B
SACS sacsin molecular chaperone
SCN1B sodium channel, voltage gated, type I beta subunit
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOBP sine oculis binding protein homolog (Drosophila)
STK16 serine/threonine kinase 16
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THOP1 thimet oligopeptidase 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM180 transmembrane protein 180
TNS2 tensin 2
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZNF480 zinc finger protein 480
ZNF574 zinc finger protein 574
ZNF586 zinc finger protein 586
ZNF692 zinc finger protein 692