felodipine-965 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the felodipine-965 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ATF3 activating transcription factor 3
AURKA aurora kinase A
BHLHE40 basic helix-loop-helix family, member e40
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKN2AIP CDKN2A interacting protein
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CRELD1 cysteine-rich with EGF-like domains 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DLX2 distal-less homeobox 2
DSCAM Down syndrome cell adhesion molecule
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA1 ephrin-A1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM188A family with sequence similarity 188, member A
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2AI histone cluster 1, H2ai
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IER5 immediate early response 5
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCL1 myeloid cell leukemia 1
MED6 mediator complex subunit 6
MMP19 matrix metallopeptidase 19
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-1 NK3 homeobox 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PAQR6 progestin and adipoQ receptor family member VI
PER1 period circadian clock 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTBP2 polypyrimidine tract binding protein 2
PVT1 Pvt1 oncogene (non-protein coding)
RCAN1 regulator of calcineurin 1
RND1 Rho family GTPase 1
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRA2A transformer 2 alpha homolog (Drosophila)
TRIB1 tribbles pseudokinase 1
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
USP36 ubiquitin specific peptidase 36
ZBTB10 zinc finger and BTB domain containing 10
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ANKRD36 ankyrin repeat domain 36
APOC1 apolipoprotein C-I
ARHGAP10 Rho GTPase activating protein 10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C17ORF70 chromosome 17 open reading frame 70
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CARD8 caspase recruitment domain family, member 8
CENPQ centromere protein Q
CLSPN claspin
CROT carnitine O-octanoyltransferase
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPDC1 DEP domain containing 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EHD3 EH-domain containing 3
EPHA4 EPH receptor A4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FAAH fatty acid amide hydrolase
FAM134B family with sequence similarity 134, member B
FANCE Fanconi anemia, complementation group E
FBXO3 F-box protein 3
FPGT fucose-1-phosphate guanylyltransferase
FZD2 frizzled class receptor 2
GALT galactose-1-phosphate uridylyltransferase
GDAP2 ganglioside induced differentiation associated protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRASP1 G protein-coupled receptor associated sorting protein 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HPSE heparanase
IFI35 interferon-induced protein 35
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
JRKL JRK-like
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIFC1 kinesin family member C1
KRT13 keratin 13, type I
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAP7D3 MAP7 domain containing 3
MCOLN1 mucolipin 1
MTMR6 myotubularin related protein 6
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NT5E 5'-nucleotidase, ecto (CD73)
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PEX26 peroxisomal biogenesis factor 26
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PYCRL pyrroline-5-carboxylate reductase-like
RAB33B RAB33B, member RAS oncogene family
RBL1 retinoblastoma-like 1
RLN2 relaxin 2
RNF31 ring finger protein 31
RPL23AP7 ribosomal protein L23a pseudogene 7
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPANXC SPANX family, member C
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SUGP1 SURP and G patch domain containing 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TPCN1 two pore segment channel 1
TRIM5 tripartite motif containing 5
TSPAN1 tetraspanin 1
TWF2 twinfilin actin binding protein 2
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
ZBTB39 zinc finger and BTB domain containing 39
ZNF432 zinc finger protein 432
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF778 zinc finger protein 778