fatty acid beta-oxidation multienzyme complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT). (Gene Ontology, GO_0036125)
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Genes

68 proteins co-occuring with the fatty acid beta-oxidation multienzyme complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 2.47084
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.96638
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 1.77665
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.63005
BPGM 2,3-bisphosphoglycerate mutase 1.32762
ECI2 enoyl-CoA delta isomerase 2 1.30067
ECI1 enoyl-CoA delta isomerase 1 1.21376
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 1.06853
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.934544
ACAA1 acetyl-CoA acyltransferase 1 0.917644
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.906926
GRIP2 glutamate receptor interacting protein 2 0.886551
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.859392
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 0.843318
ACOT2 acyl-CoA thioesterase 2 0.811193
LCLAT1 lysocardiolipin acyltransferase 1 0.771819
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.712351
ACADL acyl-CoA dehydrogenase, long chain 0.688576
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.685517
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.672026
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.662072
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.642286
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.626057
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.617133
FTCD formimidoyltransferase cyclodeaminase 0.593492
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.588875
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.567169
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.563847
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.563847
TSPAN1 tetraspanin 1 0.537827
ACADVL acyl-CoA dehydrogenase, very long chain 0.531258
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.510826
ACAA2 acetyl-CoA acyltransferase 2 0.503506
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.493775
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.491752
DHFR dihydrofolate reductase 0.486904
PGAM2 phosphoglycerate mutase 2 (muscle) 0.4608
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.457606
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.454019
HADH hydroxyacyl-CoA dehydrogenase 0.452427
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.430253
MDH1 malate dehydrogenase 1, NAD (soluble) 0.425531
PGAM1 phosphoglycerate mutase 1 (brain) 0.424353
FGF19 fibroblast growth factor 19 0.421212
AMPD1 adenosine monophosphate deaminase 1 0.409869
TAZ tafazzin 0.405971
FOLR1 folate receptor 1 (adult) 0.395098
CAT catalase 0.376202
ACAT1 acetyl-CoA acetyltransferase 1 0.362422
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.358609
HSPE1 heat shock 10kDa protein 1 0.348725
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.321201
PRMT1 protein arginine methyltransferase 1 0.300682
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.266042
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.25547
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.234533
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.233101
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.232744
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.232029
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.232029
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.225267
SIAE sialic acid acetylesterase 0.22385
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.217861
TARDBP TAR DNA binding protein 0.204378
IMMT inner membrane protein, mitochondrial 0.200663
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.19733
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.180339
PHB prohibitin 0.167611