fatty acid alpha-oxidation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway. (Gene Ontology, GO_0001561)
External Link http://amigo.geneontology.org/amigo/term/GO:0001561
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6 genes participating in the fatty acid alpha-oxidation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
HACL1 2-hydroxyacyl-CoA lyase 1
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
PEX13 peroxisomal biogenesis factor 13
PHYH phytanoyl-CoA 2-hydroxylase
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2