fatty acid β-oxidation Gene Set

Dataset HumanCyc Pathways
Category structural or functional annotations
Type pathway
Description A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). (Gene Ontology, GO_0006635)
External Link http://humancyc.org/HUMAN/NEW-IMAGE?type=PATHWAY&object=FAO-PWY
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Genes

16 proteins participating in the fatty acid β-oxidation pathway from the HumanCyc Pathways dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACADL acyl-CoA dehydrogenase, long chain
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACSL5 acyl-CoA synthetase long-chain family member 5
ACSL6 acyl-CoA synthetase long-chain family member 6
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
ECI1 enoyl-CoA delta isomerase 1
HADH hydroxyacyl-CoA dehydrogenase
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
SCP2 sterol carrier protein 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2