fate Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

314 genes co-occuring with the biological term fate in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACSL5 acyl-CoA synthetase long-chain family member 5
ACVR2A activin A receptor, type IIA
ACVRL1 activin A receptor type II-like 1
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA2 annexin A2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
AREG amphiregulin
ARX aristaless related homeobox
ASCL1 achaete-scute family bHLH transcription factor 1
ATF3 activating transcription factor 3
ATF6 activating transcription factor 6
ATM ATM serine/threonine kinase
AURKB aurora kinase B
B2M beta-2-microglobulin
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDKRB2 bradykinin receptor B2
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C5AR1 complement component 5a receptor 1
CALCA calcitonin-related polypeptide alpha
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCAR2 cell cycle and apoptosis regulator 2
CCNB1 cyclin B1
CCND2 cyclin D2
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDCA4 cell division cycle associated 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2AIP CDKN2A interacting protein
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CERK ceramide kinase
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CLU clusterin
COL4A2 collagen, type IV, alpha 2
CPB2 carboxypeptidase B2 (plasma)
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DACH1 dachshund family transcription factor 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DLK1 delta-like 1 homolog (Drosophila)
DLX1 distal-less homeobox 1
DNM1L dynamin 1-like
DSPP dentin sialophosphoprotein
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5A eukaryotic translation initiation factor 5A
ELAVL1 ELAV like RNA binding protein 1
EN2 engrailed homeobox 2
ENDOV endonuclease V
EP400 E1A binding protein p400
EPHB2 EPH receptor B2
ERF Ets2 repressor factor
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ETV6 ets variant 6
EZR ezrin
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FATE1 fetal and adult testis expressed 1
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FEM1A fem-1 homolog a (C. elegans)
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FMR1 fragile X mental retardation 1
FOXA2 forkhead box A2
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GDF15 growth differentiation factor 15
GMNN geminin, DNA replication inhibitor
GPC4 glypican 4
GRM4 glutamate receptor, metabotropic 4
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
H2AFX H2A histone family, member X
HAVCR2 hepatitis A virus cellular receptor 2
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HEXIM1 hexamethylene bis-acetamide inducible 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIPK2 homeodomain interacting protein kinase 2
HIST1H3B histone cluster 1, H3b
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXB1 homeobox B1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL17RD interleukin 17 receptor D
IL1B interleukin 1, beta
IL4 interleukin 4
IL7 interleukin 7
IRF3 interferon regulatory factor 3
ITGA6 integrin, alpha 6
JAK2 Janus kinase 2
JARID2 jumonji, AT rich interactive domain 2
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KAT8 K(lysine) acetyltransferase 8
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KITLG KIT ligand
KLF4 Kruppel-like factor 4 (gut)
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS2 large tumor suppressor kinase 2
LDLR low density lipoprotein receptor
LGALS9 lectin, galactoside-binding, soluble, 9
LRP5 low density lipoprotein receptor-related protein 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MIR126 microRNA 126
MIR137 microRNA 137
MIR145 microRNA 145
MIR155 microRNA 155
MIR204 microRNA 204
MIR223 microRNA 223
MIR299 microRNA 299
MIR30C2 microRNA 30c-2
MIR31 microRNA 31
MIR335 microRNA 335
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP2 matrix metallopeptidase 2
MTA3 metastasis associated 1 family, member 3
MUC1 mucin 1, cell surface associated
MVB12A multivesicular body subunit 12A
MVB12B multivesicular body subunit 12B
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NANOG Nanog homeobox
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-2 NK2 homeobox 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRL neural retina leucine zipper
NUMB numb homolog (Drosophila)
NUP107 nucleoporin 107kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OTX2 orthodenticle homeobox 2
PABPC1 poly(A) binding protein, cytoplasmic 1
PANX3 pannexin 3
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX3 paired box 3
PAX6 paired box 6
PCGF1 polycomb group ring finger 1
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POU4F2 POU class 4 homeobox 2
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM16 PR domain containing 16
PRF1 perforin 1 (pore forming protein)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRMT5 protein arginine methyltransferase 5
PRNP prion protein
PROM1 prominin 1
PROX1 prospero homeobox 1
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTF1A pancreas specific transcription factor, 1a
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB5A RAB5A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM5 RNA binding motif protein 5
RBX1 ring-box 1, E3 ubiquitin protein ligase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REN renin
RGS3 regulator of G-protein signaling 3
RHOA ras homolog family member A
RIN1 Ras and Rab interactor 1
RMST rhabdomyosarcoma 2 associated transcript (non-protein coding)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX2 runt-related transcription factor 2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SGPL1 sphingosine-1-phosphate lyase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SMAD7 SMAD family member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX1 SRY (sex determining region Y)-box 1
SOX10 SRY (sex determining region Y)-box 10
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SPI1 Spi-1 proto-oncogene
SPINT1 serine peptidase inhibitor, Kunitz type 1
SREBF1 sterol regulatory element binding transcription factor 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM109 transmembrane protein 109
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM33 tripartite motif containing 33
TSLP thymic stromal lymphopoietin
TTR transthyretin
TWIST1 twist family bHLH transcription factor 1
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP9X ubiquitin specific peptidase 9, X-linked
VEGFA vascular endothelial growth factor A
WBP1 WW domain binding protein 1
WDR62 WD repeat domain 62
WNT7A wingless-type MMTV integration site family, member 7A
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
YBX1 Y box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFP42 ZFP42 zinc finger protein
ZYX zyxin