famprofazone-3928 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the famprofazone-3928 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AMACR alpha-methylacyl-CoA racemase
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOL6 apolipoprotein L, 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL2 B-cell CLL/lymphoma 2
C19ORF66 chromosome 19 open reading frame 66
C7ORF69 chromosome 7 open reading frame 69
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD9 caspase recruitment domain family, member 9
CCDC87 coiled-coil domain containing 87
CD6 CD6 molecule
CD70 CD70 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLEC3B C-type lectin domain family 3, member B
CLTA clathrin, light chain A
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
ERCC2 excision repair cross-complementation group 2
ETV7 ets variant 7
FAIM2 Fas apoptotic inhibitory molecule 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FNDC4 fibronectin type III domain containing 4
FST follistatin
GAL3ST4 galactose-3-O-sulfotransferase 4
GAP43 growth associated protein 43
GJD2 gap junction protein, delta 2, 36kDa
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRM4 glutamate receptor, metabotropic 4
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H3J histone cluster 1, H3j
HYAL3 hyaluronoglucosaminidase 3
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
IQCA1 IQ motif containing with AAA domain 1
JAM2 junctional adhesion molecule 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
KLK15 kallikrein-related peptidase 15
KLK8 kallikrein-related peptidase 8
KXD1 KxDL motif containing 1
L1CAM L1 cell adhesion molecule
L1TD1 LINE-1 type transposase domain containing 1
LCAT lecithin-cholesterol acyltransferase
LEFTY2 left-right determination factor 2
LGALS13 lectin, galactoside-binding, soluble, 13
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00312 long intergenic non-protein coding RNA 312
MAGEA6 melanoma antigen family A6
MAGEC1 melanoma antigen family C1
MAP1A microtubule-associated protein 1A
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MIP major intrinsic protein of lens fiber
MOG myelin oligodendrocyte glycoprotein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
MYL10 myosin, light chain 10, regulatory
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OSBPL3 oxysterol binding protein-like 3
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PDZD2 PDZ domain containing 2
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIP prolactin-induced protein
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLK3 polo-like kinase 3
PPARD peroxisome proliferator-activated receptor delta
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSAT1 phosphoserine aminotransferase 1
PURG purine-rich element binding protein G
RBMS2 RNA binding motif, single stranded interacting protein 2
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SH3D21 SH3 domain containing 21
SIM2 single-minded family bHLH transcription factor 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
SORBS2 sorbin and SH3 domain containing 2
STATH statherin
STOML1 stomatin (EPB72)-like 1
SYNDIG1 synapse differentiation inducing 1
SYT11 synaptotagmin XI
TAOK1 TAO kinase 1
TEX14 testis expressed 14
UBA6 ubiquitin-like modifier activating enzyme 6
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACYP1 acylphosphatase 1, erythrocyte (common) type
ALS2CL ALS2 C-terminal like
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BEX4 brain expressed, X-linked 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C5AR2 complement component 5a receptor 2
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CD83 CD83 molecule
CGA glycoprotein hormones, alpha polypeptide
CISH cytokine inducible SH2-containing protein
CLDN1 claudin 1
CLEC4E C-type lectin domain family 4, member E
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNTN1 contactin 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EML4 echinoderm microtubule associated protein like 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXO22 F-box protein 22
FER fer (fps/fes related) tyrosine kinase
FFAR2 free fatty acid receptor 2
FOXD1 forkhead box D1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRC5D G protein-coupled receptor, class C, group 5, member D
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSF2BP heat shock transcription factor 2 binding protein
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFNA17 interferon, alpha 17
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD20 potassium channel tetramerization domain containing 20
KRT83 keratin 83, type II
LMCD1 LIM and cysteine-rich domains 1
LOC257152 uncharacterized LOC257152
LRP3 low density lipoprotein receptor-related protein 3
MAL mal, T-cell differentiation protein
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCC mutated in colorectal cancers
METTL16 methyltransferase like 16
MFAP2 microfibrillar-associated protein 2
MOCS3 molybdenum cofactor synthesis 3
MTERF4 mitochondrial transcription termination factor 4
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NOTCH4 notch 4
NPM3 nucleophosmin/nucleoplasmin 3
NT5E 5'-nucleotidase, ecto (CD73)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLCD1 phospholipase C, delta 1
PRF1 perforin 1 (pore forming protein)
RAB40AL RAB40A, member RAS oncogene family-like
RHOBTB2 Rho-related BTB domain containing 2
RND1 Rho family GTPase 1
RNF121 ring finger protein 121
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF208 ring finger protein 208
RPL23AP32 ribosomal protein L23a pseudogene 32
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGPP1 sphingosine-1-phosphate phosphatase 1
SPAG4 sperm associated antigen 4
ST5 suppression of tumorigenicity 5
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D19 TBC1 domain family, member 19
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNRC6B trinucleotide repeat containing 6B
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSC22D4 TSC22 domain family, member 4
TSPAN9 tetraspanin 9
TTLL1 tubulin tyrosine ligase-like family member 1
UBTD1 ubiquitin domain containing 1
UPP1 uridine phosphorylase 1
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
ZNF205 zinc finger protein 205
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF675 zinc finger protein 675
ZNF701 zinc finger protein 701
ZW10 zw10 kinetochore protein