famprofazone-3753 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the famprofazone-3753 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAM22 ADAM metallopeptidase domain 22
ADORA1 adenosine A1 receptor
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPL alkaline phosphatase, liver/bone/kidney
AMN amnion associated transmembrane protein
ANGPTL4 angiopoietin-like 4
ARHGAP28 Rho GTPase activating protein 28
ARSA arylsulfatase A
BLZF1 basic leucine zipper nuclear factor 1
BRS3 bombesin-like receptor 3
C22ORF31 chromosome 22 open reading frame 31
CCDC170 coiled-coil domain containing 170
CCDC57 coiled-coil domain containing 57
CD1A CD1a molecule
CDK18 cyclin-dependent kinase 18
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CISH cytokine inducible SH2-containing protein
CLTCL1 clathrin, heavy chain-like 1
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
CPEB3 cytoplasmic polyadenylation element binding protein 3
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DBT dihydrolipoamide branched chain transacylase E2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDA ectodysplasin A
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
FLRT2 fibronectin leucine rich transmembrane protein 2
GFRA1 GDNF family receptor alpha 1
GLP1R glucagon-like peptide 1 receptor
GP6 glycoprotein VI (platelet)
GPR157 G protein-coupled receptor 157
HIC2 hypermethylated in cancer 2
ING4 inhibitor of growth family, member 4
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM2 junctional adhesion molecule 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL25 kelch-like family member 25
KRT16 keratin 16, type I
KRT32 keratin 32, type I
LARP7 La ribonucleoprotein domain family, member 7
LINC00216 long intergenic non-protein coding RNA 216
LINC00652 long intergenic non-protein coding RNA 652
MAML3 mastermind-like 3 (Drosophila)
MON2 MON2 homolog (S. cerevisiae)
MORC1 MORC family CW-type zinc finger 1
MPPE1 metallophosphoesterase 1
MUC3B mucin 3B, cell surface associated
MYOZ3 myozenin 3
NPR1 natriuretic peptide receptor 1
NPTX1 neuronal pentraxin I
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OXCT2 3-oxoacid CoA transferase 2
PBX2 pre-B-cell leukemia homeobox 2
PKNOX2 PBX/knotted 1 homeobox 2
PLAG1 pleiomorphic adenoma gene 1
PLXNA2 plexin A2
PLXNB1 plexin B1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRB1 proline-rich protein BstNI subfamily 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PTN pleiotrophin
PTPRH protein tyrosine phosphatase, receptor type, H
RHAG Rh-associated glycoprotein
RND1 Rho family GTPase 1
RUNDC3A RUN domain containing 3A
RXRB retinoid X receptor, beta
SAFB scaffold attachment factor B
SAMD14 sterile alpha motif domain containing 14
SCARF1 scavenger receptor class F, member 1
SFTPB surfactant protein B
SLAMF7 SLAM family member 7
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC25A30 solute carrier family 25, member 30
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SNCAIP synuclein, alpha interacting protein
SOSTDC1 sclerostin domain containing 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAT5A signal transducer and activator of transcription 5A
TAS2R1 taste receptor, type 2, member 1
TBCD tubulin folding cofactor D
THSD4 thrombospondin, type I, domain containing 4
TP53I11 tumor protein p53 inducible protein 11
TRA T cell receptor alpha locus
TSSK2 testis-specific serine kinase 2
WSB1 WD repeat and SOCS box containing 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZC3H7B zinc finger CCCH-type containing 7B
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANXA10 annexin A10
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AURKC aurora kinase C
C22ORF29 chromosome 22 open reading frame 29
C5ORF42 chromosome 5 open reading frame 42
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CINP cyclin-dependent kinase 2 interacting protein
CRELD1 cysteine-rich with EGF-like domains 1
CRMP1 collapsin response mediator protein 1
CYB5R2 cytochrome b5 reductase 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCLRE1A DNA cross-link repair 1A
EDN1 endothelin 1
EXOC5 exocyst complex component 5
FAM118A family with sequence similarity 118, member A
FAM120C family with sequence similarity 120C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FGF23 fibroblast growth factor 23
FKRP fukutin related protein
FSD1 fibronectin type III and SPRY domain containing 1
GALT galactose-1-phosphate uridylyltransferase
GJC1 gap junction protein, gamma 1, 45kDa
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDAC5 histone deacetylase 5
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFI6 interferon, alpha-inducible protein 6
IL11RA interleukin 11 receptor, alpha
KIFC1 kinesin family member C1
LINC00472 long intergenic non-protein coding RNA 472
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MED31 mediator complex subunit 31
MGC12488
MNX1 motor neuron and pancreas homeobox 1
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MTMR12 myotubularin related protein 12
MX1 MX dynamin-like GTPase 1
MYLIP myosin regulatory light chain interacting protein
NARFL nuclear prelamin A recognition factor-like
NCS1 neuronal calcium sensor 1
NPM3 nucleophosmin/nucleoplasmin 3
NSD1 nuclear receptor binding SET domain protein 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PICK1 protein interacting with PRKCA 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODXL2 podocalyxin-like 2
PRPH peripherin
PWAR5 Prader Willi/Angelman region RNA 5
RAB27B RAB27B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGCC regulator of cell cycle
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUNX1-IT1 RUNX1 intronic transcript 1
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SNORA21 small nucleolar RNA, H/ACA box 21
STARD5 StAR-related lipid transfer (START) domain containing 5
STK16 serine/threonine kinase 16
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPCN1 two pore segment channel 1
TRAC T cell receptor alpha constant
UGT8 UDP glycosyltransferase 8
VEZT vezatin, adherens junctions transmembrane protein
VGLL3 vestigial-like family member 3
XAB2 XPA binding protein 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF222 zinc finger protein 222
ZNF480 zinc finger protein 480
ZNF665 zinc finger protein 665
ZNF667 zinc finger protein 667
ZNF702P zinc finger protein 702, pseudogene
ZNF93 zinc finger protein 93