failure of blastocyst to hatch from the zona pellucida Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description the hatching of the cellular blastocyst from the zona pellucida, the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, fails to occur (Mammalian Phenotype Ontology, MP_0003694)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003694
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Genes

29 gene mutations causing the failure of blastocyst to hatch from the zona pellucida phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
CDCA8 cell division cycle associated 8
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK11A cyclin-dependent kinase 11A
CDX2 caudal type homeobox 2
CHEK1 checkpoint kinase 1
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
ECT2 epithelial cell transforming 2
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
KIF11 kinesin family member 11
KLF5 Kruppel-like factor 5 (intestinal)
MCL1 myeloid cell leukemia 1
NLE1 notchless homolog 1 (Drosophila)
PARG poly (ADP-ribose) glycohydrolase
PDCD2 programmed cell death 2
RBBP8 retinoblastoma binding protein 8
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SRRT serrate, RNA effector molecule
SYF2 SYF2 pre-mRNA-splicing factor
TGS1 trimethylguanosine synthase 1
THOC1 THO complex 1
TSHZ2 teashirt zinc finger homeobox 2
TXN thioredoxin
VAV1 vav 1 guanine nucleotide exchange factor
VEZT vezatin, adherens junctions transmembrane protein
ZNF830 zinc finger protein 830