eye cancer cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A cell of a cancerous growth in any part of the eye. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000579)
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Genes

241 proteins co-occuring with the tissue eye cancer cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
RBP3 retinol binding protein 3, interstitial 1.66307
CRX cone-rod homeobox 1.54681
RB1 retinoblastoma 1 1.47335
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 1.31559
ZBED4 zinc finger, BED-type containing 4 1.24967
ARR3 arrestin 3, retinal (X-arrestin) 1.24253
NRL neural retina leucine zipper 1.16249
TRHDE thyrotropin-releasing hormone degrading enzyme 1.16027
ASMT acetylserotonin O-methyltransferase 1.15008
SH3BP4 SH3-domain binding protein 4 1.12172
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.10358
SAG S-antigen; retina and pineal gland (arrestin) 1.06515
ENO2 enolase 2 (gamma, neuronal) 1.04708
NR2E3 nuclear receptor subfamily 2, group E, member 3 1.03434
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.983688
GRIK5 glutamate receptor, ionotropic, kainate 5 0.953409
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.939206
EGFLAM EGF-like, fibronectin type III and laminin G domains 0.937059
RHO rhodopsin 0.929764
RCVRN recoverin 0.925051
SUSD2 sushi domain containing 2 0.871483
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.836575
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.801042
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.794792
TP53 tumor protein p53 0.780648
CDK10 cyclin-dependent kinase 10 0.768197
NUB1 negative regulator of ubiquitin-like proteins 1 0.762811
PAX6 paired box 6 0.74174
CETN1 centrin, EF-hand protein, 1 0.7146
OTX2 orthodenticle homeobox 2 0.698625
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.689634
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.676987
CRH corticotropin releasing hormone 0.674543
KIF4A kinesin family member 4A 0.673321
CRHR1 corticotropin releasing hormone receptor 1 0.668843
MVP major vault protein 0.627485
SAFB scaffold attachment factor B 0.610541
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.606514
ILK integrin-linked kinase 0.601283
BAX BCL2-associated X protein 0.580818
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.578816
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.578816
NR2E1 nuclear receptor subfamily 2, group E, member 1 0.578016
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.577615
RS1 retinoschisin 1 0.575216
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.574017
RHAG Rh-associated glycoprotein 0.573616
PGPEP1 pyroglutamyl-peptidase I 0.573616
PXDN peroxidasin 0.571219
CXADR coxsackie virus and adenovirus receptor 0.56603
GJA3 gap junction protein, alpha 3, 46kDa 0.54217
CETN2 centrin, EF-hand protein, 2 0.540585
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.531879
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.531089
FASN fatty acid synthase 0.516104
RCOR1 REST corepressor 1 0.50079
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.494918
PDZD4 PDZ domain containing 4 0.494136
AXL AXL receptor tyrosine kinase 0.464561
PLCB2 phospholipase C, beta 2 0.461852
CIITA class II, major histocompatibility complex, transactivator 0.461465
ANXA5 annexin A5 0.443347
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.442962
TICAM2 toll-like receptor adaptor molecule 2 0.439123
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.430695
ULBP2 UL16 binding protein 2 0.42993
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.42649
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.422673
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.420004
CNTN6 contactin 6 0.417337
POU3F2 POU class 3 homeobox 2 0.414673
VSX2 visual system homeobox 2 0.414293
RLBP1 retinaldehyde binding protein 1 0.412011
ESRRB estrogen-related receptor beta 0.410491
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.402523
CDK1 cyclin-dependent kinase 1 0.400628
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.393442
HMGA2 high mobility group AT-hook 2 0.388912
CCNE2 cyclin E2 0.378372
BAG3 BCL2-associated athanogene 3 0.36825
ESD esterase D 0.366381
CRYAB crystallin, alpha B 0.363766
EPCAM epithelial cell adhesion molecule 0.358546
TMEM132D transmembrane protein 132D 0.357058
ACACB acetyl-CoA carboxylase beta 0.356686
DCD dermcidin 0.352598
CD276 CD276 molecule 0.345558
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.342233
SUMO2 small ubiquitin-like modifier 2 0.335233
DCT dopachrome tautomerase 0.332294
EPS15 epidermal growth factor receptor pathway substrate 15 0.32497
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.324239
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.318407
TXNDC9 thioredoxin domain containing 9 0.316951
GRK1 G protein-coupled receptor kinase 1 0.314772
GTF2B general transcription factor IIB 0.308612
MMP2 matrix metallopeptidase 2 0.299601
PARP1 poly (ADP-ribose) polymerase 1 0.298524
KDM1A lysine (K)-specific demethylase 1A 0.296372
TIMP2 TIMP metallopeptidase inhibitor 2 0.293508
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 0.290592
INSR insulin receptor 0.288514
PDCL phosducin-like 0.284253
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.279659
VIP vasoactive intestinal peptide 0.278955
CRYAA crystallin, alpha A 0.278955
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.269867
CDK5 cyclin-dependent kinase 5 0.269867
TGFB1 transforming growth factor, beta 1 0.268137
AK1 adenylate kinase 1 0.263669
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.260945
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.2559
CYR61 cysteine-rich, angiogenic inducer, 61 0.250627
MCM2 minichromosome maintenance complex component 2 0.249977
PTER phosphotriesterase related 0.249653
PPARA peroxisome proliferator-activated receptor alpha 0.24804
BIRC5 baculoviral IAP repeat containing 5 0.247399
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.247399
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.24288
HLA-B major histocompatibility complex, class I, B 0.242054
PDC phosducin 0.240216
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.238108
ELK1 ELK1, member of ETS oncogene family 0.23604
PHYH phytanoyl-CoA 2-hydroxylase 0.235167
GFAP glial fibrillary acidic protein 0.233446
LRP6 low density lipoprotein receptor-related protein 6 0.232039
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.231206
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.228764
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.220152
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.217833
H2AFX H2A histone family, member X 0.217554
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.216126
NDRG1 N-myc downstream regulated 1 0.214954
INS insulin 0.213291
CCNE1 cyclin E1 0.213112
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 0.212848
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.202512
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.200418
ADRBK2 adrenergic, beta, receptor kinase 2 0.198846
GTSE1 G-2 and S-phase expressed 1 0.198614
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.197481
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.197292
DRAM1 DNA-damage regulated autophagy modulator 1 0.196914
E2F4 E2F transcription factor 4, p107/p130-binding 0.196238
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.19583
TOP1 topoisomerase (DNA) I 0.195233
FADS2 fatty acid desaturase 2 0.195199
PPOX protoporphyrinogen oxidase 0.195176
MIRLET7C microRNA let-7c 0.195125
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.19442
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.194166
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.194153
MYH10 myosin, heavy chain 10, non-muscle 0.194144
MIR22 microRNA 22 0.194113
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.194042
NUTM1 NUT midline carcinoma, family member 1 0.193623
MIR10B microRNA 10b 0.193459
BHLHE23 basic helix-loop-helix family, member e23 0.193075
FABP12 fatty acid binding protein 12 0.192955
ANOS1 anosmin 1 0.192664
MDM4 MDM4, p53 regulator 0.191965
MIR17 microRNA 17 0.19163
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.190858
ADRA2C adrenoceptor alpha 2C 0.190858
UCN urocortin 0.190746
UCN3 urocortin 3 0.190218
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.189985
PDCD1LG2 programmed cell death 1 ligand 2 0.189746
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.189538
MEIS1 Meis homeobox 1 0.189289
JAG2 jagged 2 0.189122
IRS1 insulin receptor substrate 1 0.188492
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.188242
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.18797
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.187583
H3F3B H3 histone, family 3B (H3.3B) 0.187389
H3F3A H3 histone, family 3A 0.187389
EP300 E1A binding protein p300 0.187269
SNAI1 snail family zinc finger 1 0.187182
CAPNS1 calpain, small subunit 1 0.186893
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.186604
GLB1 galactosidase, beta 1 0.186476
NEFL neurofilament, light polypeptide 0.186467
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.185625
FGF3 fibroblast growth factor 3 0.185404
DRD4 dopamine receptor D4 0.185333
IFNGR1 interferon gamma receptor 1 0.184512
IGF1 insulin-like growth factor 1 (somatomedin C) 0.184225
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.183919
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.183018
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.181819
MAGEA3 melanoma antigen family A3 0.181546
KIRREL2 kin of IRRE like 2 (Drosophila) 0.180587
MIR191 microRNA 191 0.180073
SP6 Sp6 transcription factor 0.17913
IL2 interleukin 2 0.178348
RD3 retinal degeneration 3 0.17765
PAX3 paired box 3 0.176384
TFF2 trefoil factor 2 0.176304
CD80 CD80 molecule 0.176122
TFF1 trefoil factor 1 0.17573
MSI1 musashi RNA-binding protein 1 0.175003
FABP9 fatty acid binding protein 9, testis 0.174221
CDKN2A cyclin-dependent kinase inhibitor 2A 0.173252
HLA-A major histocompatibility complex, class I, A 0.172301
KIRREL kin of IRRE like (Drosophila) 0.170994
AANAT aralkylamine N-acetyltransferase 0.170715
DEK DEK proto-oncogene 0.169707
RELN reelin 0.163777
B2M beta-2-microglobulin 0.162222
IL1RN interleukin 1 receptor antagonist 0.161937
NOVA2 neuro-oncological ventral antigen 2 0.161684
MAP2 microtubule-associated protein 2 0.158822
E2F3 E2F transcription factor 3 0.158497
FAM195A family with sequence similarity 195, member A 0.157452
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.155971
FOLR1 folate receptor 1 (adult) 0.153837
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.153837
CD82 CD82 molecule 0.153621
SEBOX SEBOX homeobox 0.152583
CD177 CD177 molecule 0.152304
FLT4 fms-related tyrosine kinase 4 0.151344
CD70 CD70 molecule 0.151172
NCOR1 nuclear receptor corepressor 1 0.151057
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.150885
FGFR4 fibroblast growth factor receptor 4 0.150244
NANOG Nanog homeobox 0.149358
GRIK1 glutamate receptor, ionotropic, kainate 1 0.147581
SHBG sex hormone-binding globulin 0.147581
SFRP2 secreted frizzled-related protein 2 0.147081
FN1 fibronectin 1 0.146831
FKBP1A FK506 binding protein 1A, 12kDa 0.146254
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.146061
MYH9 myosin, heavy chain 9, non-muscle 0.145997
FECH ferrochelatase 0.145352
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.14522
CYLD cylindromatosis (turban tumor syndrome) 0.144823
EPHA2 EPH receptor A2 0.144691
CDC25A cell division cycle 25A 0.144691
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.143963
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.143691