extrinsic apoptotic signaling pathway in absence of ligand Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered. (Gene Ontology, GO_0097192)
External Link http://amigo.geneontology.org/amigo/term/GO:0097192
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Genes

36 genes participating in the extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BOK BCL2-related ovarian killer
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
ERBB3 erb-b2 receptor tyrosine kinase 3
EYA2 EYA transcriptional coactivator and phosphatase 2
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FOXO3 forkhead box O3
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL4 interleukin 4
ITGAV integrin, alpha V
ITM2B integral membrane protein 2B
KITLG KIT ligand
LCN2 lipocalin 2
MCL1 myeloid cell leukemia 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MOAP1 modulator of apoptosis 1
NGF nerve growth factor (beta polypeptide)
ST20 suppressor of tumorigenicity 20