extraembryonic tissue Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The structure outside the embryonic body; e.g., those membranes involved with the embryos protection and nutrition which are discarded at birth without being incorporated in its body. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003360)
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Genes

336 proteins co-occuring with the tissue extraembryonic tissue in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
GATA6 GATA binding protein 6 1.79549
AFP alpha-fetoprotein 1.62707
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.60316
OTX2 orthodenticle homeobox 2 1.58732
GATA4 GATA binding protein 4 1.56574
MNX1 motor neuron and pancreas homeobox 1 1.47662
BMP4 bone morphogenetic protein 4 1.39559
EOMES eomesodermin 1.33003
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.32371
IHH indian hedgehog 1.31063
SOX17 SRY (sex determining region Y)-box 17 1.24922
RFTN2 raftlin family member 2 1.24208
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.20511
NANOG Nanog homeobox 1.20022
EED embryonic ectoderm development 1.17669
ESX1 ESX homeobox 1 1.17181
SFMBT2 Scm-like with four mbt domains 2 1.15761
ERICH1 glutamate-rich 1 1.13368
HESX1 HESX homeobox 1 1.11464
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 1.08015
TSSC4 tumor suppressing subtransferable candidate 4 1.04885
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.0484
BPTF bromodomain PHD finger transcription factor 1.04708
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.04093
HNF1B HNF1 homeobox B 1.03566
ECEL1 endothelin converting enzyme-like 1 1.02425
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 1.02162
SLC39A5 solute carrier family 39 (zinc transporter), member 5 1.02075
AMOT angiomotin 1.01593
ZFP42 ZFP42 zinc finger protein 1.01506
LEFTY2 left-right determination factor 2 1.01462
ESRRB estrogen-related receptor beta 1.00283
EVL Enah/Vasp-like 0.981084
ASCL2 achaete-scute family bHLH transcription factor 2 0.975015
CDX2 caudal type homeobox 2 0.971984
OCM2 oncomodulin 2 0.970686
SMAD2 SMAD family member 2 0.970253
OCM oncomodulin 0.966793
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.963767
SNX2 sorting nexin 2 0.962039
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.958154
EMB embigin 0.957722
CUL4B cullin 4B 0.955565
ZDBF2 zinc finger, DBF-type containing 2 0.945656
MOSPD2 motile sperm domain containing 2 0.942645
FOXA2 forkhead box A2 0.936199
ZNF18 zinc finger protein 18 0.934911
IGF2 insulin-like growth factor 2 0.934482
TTR transthyretin 0.931908
OTX1 orthodenticle homeobox 1 0.904553
TGFB1 transforming growth factor, beta 1 0.89647
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.893496
FN1 fibronectin 1 0.866842
ACSS3 acyl-CoA synthetase short-chain family member 3 0.8601
KLF16 Kruppel-like factor 16 0.850005
WNT3A wingless-type MMTV integration site family, member 3A 0.844126
FBLN7 fibulin 7 0.837833
LAMA1 laminin, alpha 1 0.836156
HAND1 heart and neural crest derivatives expressed 1 0.826942
ACVR1B activin A receptor, type IB 0.807716
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.786468
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.783141
PELO pelota homolog (Drosophila) 0.780648
HNF4A hepatocyte nuclear factor 4, alpha 0.780232
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.754124
LRP2 low density lipoprotein receptor-related protein 2 0.747515
STRA6 stimulated by retinoic acid 6 0.745039
PLS1 plastin 1 0.731031
FGF4 fibroblast growth factor 4 0.724863
HES4 hes family bHLH transcription factor 4 0.721166
UTF1 undifferentiated embryonic cell transcription factor 1 0.720755
APCDD1 adenomatosis polyposis coli down-regulated 1 0.718703
LEFTY1 left-right determination factor 1 0.71542
DLX4 distal-less homeobox 4 0.713369
HOXB6 homeobox B6 0.713369
HLA-G major histocompatibility complex, class I, G 0.702308
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.700671
ZNF503 zinc finger protein 503 0.695763
WTAP Wilms tumor 1 associated protein 0.691268
ACVR1C activin A receptor, type IC 0.690042
MIXL1 Mix paired-like homeobox 0.689226
SMAD4 SMAD family member 4 0.688409
ONECUT1 one cut homeobox 1 0.680248
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.679433
PITX2 paired-like homeodomain 2 0.666402
HAND2 heart and neural crest derivatives expressed 2 0.665995
OTOP1 otopetrin 1 0.663962
TFEB transcription factor EB 0.663555
FOXH1 forkhead box H1 0.659491
TEAD3 TEA domain family member 3 0.65746
PCSK6 proprotein convertase subtilisin/kexin type 6 0.656648
CBX1 chromobox homolog 1 0.653807
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.6534
TAL1 T-cell acute lymphocytic leukemia 1 0.652589
DMBT1 deleted in malignant brain tumors 1 0.649749
CCS copper chaperone for superoxide dismutase 0.648127
DUSP9 dual specificity phosphatase 9 0.644074
AMOTL2 angiomotin like 2 0.640023
SFRP5 secreted frizzled-related protein 5 0.637999
CYTH1 cytohesin 1 0.626677
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.623446
SMAD5 SMAD family member 5 0.621428
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.618603
NOG noggin 0.612958
SIX3 SIX homeobox 3 0.611346
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.598871
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 0.598871
LHX1 LIM homeobox 1 0.59646
ZSCAN4 zinc finger and SCAN domain containing 4 0.595656
MESDC2 mesoderm development candidate 2 0.595255
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.59405
DSP desmoplakin 0.590437
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 0.588832
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.588031
FOXF1 forkhead box F1 0.584823
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.580818
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.579216
IGF2R insulin-like growth factor 2 receptor 0.579216
FOXM1 forkhead box M1 0.578416
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.571619
TGIF1 TGFB-induced factor homeobox 1 0.569622
AMOTL1 angiomotin like 1 0.565232
SPNS2 spinster homolog 2 (Drosophila) 0.564833
ZNF24 zinc finger protein 24 0.558457
MTTP microsomal triglyceride transfer protein 0.550106
FUBP1 far upstream element (FUSE) binding protein 1 0.549709
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.545342
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.544152
RYBP RING1 and YY1 binding protein 0.54217
CHRD chordin 0.540585
H3F3A H3 histone, family 3A 0.539793
H3F3B H3 histone, family 3B (H3.3B) 0.539793
ERN1 endoplasmic reticulum to nucleus signaling 1 0.537021
CFC1 cripto, FRL-1, cryptic family 1 0.53346
WNT3 wingless-type MMTV integration site family, member 3 0.531484
TGIF2 TGFB-induced factor homeobox 2 0.528719
ZFP36L2 ZFP36 ring finger protein-like 2 0.527928
TLL1 tolloid-like 1 0.520829
MAP2K2 mitogen-activated protein kinase kinase 2 0.519647
ARF4 ADP-ribosylation factor 4 0.518465
ARFRP1 ADP-ribosylation factor related protein 1 0.517678
SNX1 sorting nexin 1 0.517284
POU5F1 POU class 5 homeobox 1 0.509027
HNF1A HNF1 homeobox A 0.50079
FOXP2 forkhead box P2 0.50079
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.499615
CER1 cerberus 1, DAN family BMP antagonist 0.494136
PRDM1 PR domain containing 1, with ZNF domain 0.484376
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.483206
KDM1A lysine (K)-specific demethylase 1A 0.481259
SHH sonic hedgehog 0.476979
RNF2 ring finger protein 2 0.475034
NPAT nuclear protein, ataxia-telangiectasia locus 0.464561
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.464561
HOXB7 homeobox B7 0.461465
PCSK5 proprotein convertase subtilisin/kexin type 5 0.4576
ILVBL ilvB (bacterial acetolactate synthase)-like 0.4576
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.452584
FURIN furin (paired basic amino acid cleaving enzyme) 0.450271
SOX2 SRY (sex determining region Y)-box 2 0.449501
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.445268
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.443347
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.439507
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.435289
BCOR BCL6 corepressor 0.432991
NID1 nidogen 1 0.432608
KLF4 Kruppel-like factor 4 (gut) 0.425726
EXT1 exostosin glycosyltransferase 1 0.424963
ZMIZ1 zinc finger, MIZ-type containing 1 0.424199
AKTIP AKT interacting protein 0.422292
DSPP dentin sialophosphoprotein 0.421148
FAM3B family with sequence similarity 3, member B 0.418099
TRIM28 tripartite motif containing 28 0.415053
CTHRC1 collagen triple helix repeat containing 1 0.414673
TBX3 T-box 3 0.410491
BRD2 bromodomain containing 2 0.409731
FERMT2 fermitin family member 2 0.409351
SH3GL1 SH3-domain GRB2-like 1 0.408972
KLF5 Kruppel-like factor 5 (intestinal) 0.405935
FOXD3 forkhead box D3 0.405555
HOXD12 homeobox D12 0.40025
SLC38A5 solute carrier family 38, member 5 0.40025
TF transferrin 0.394576
ZFR zinc finger RNA binding protein 0.389666
KDM5C lysine (K)-specific demethylase 5C 0.388535
FERMT1 fermitin family member 1 0.387027
TFEC transcription factor EC 0.38665
TDGF1 teratocarcinoma-derived growth factor 1 0.382131
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.381755
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.378372
GPR1 G protein-coupled receptor 1 0.373118
BMP2 bone morphogenetic protein 2 0.371245
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.363393
GLB1 galactosidase, beta 1 0.358174
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.356686
MYH9 myosin, heavy chain 9, non-muscle 0.355198
CTSZ cathepsin Z 0.354455
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.350743
CUL4A cullin 4A 0.347408
PRND prion protein 2 (dublet) 0.346668
CBX3 chromobox homolog 3 0.346298
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.345558
GPI glucose-6-phosphate isomerase 0.34334
IRX6 iroquois homeobox 6 0.342602
FGF8 fibroblast growth factor 8 (androgen-induced) 0.342233
DHDH dihydrodiol dehydrogenase (dimeric) 0.33744
DKC1 dyskeratosis congenita 1, dyskerin 0.336336
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.334865
RUNX1 runt-related transcription factor 1 0.334498
HES2 hes family bHLH transcription factor 2 0.332661
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.329727
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.329361
HOXB9 homeobox B9 0.327896
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.32753
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.32205
TJP3 tight junction protein 3 0.32132
PIAS2 protein inhibitor of activated STAT, 2 0.320227
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.316951
FZD5 frizzled class receptor 5 0.316588
TBX6 T-box 6 0.316224
PLG plasminogen 0.315861
FOXA3 forkhead box A3 0.312595
RBP4 retinol binding protein 4, plasma 0.312232
ALX4 ALX homeobox 4 0.312232
EMILIN1 elastin microfibril interfacer 1 0.311507
FZD8 frizzled class receptor 8 0.308974
CD46 CD46 molecule, complement regulatory protein 0.306444
QKI QKI, KH domain containing, RNA binding 0.305001
ALPPL2 alkaline phosphatase, placental-like 2 0.302118
GCM1 glial cells missing homolog 1 (Drosophila) 0.302118
PRPS1 phosphoribosyl pyrophosphate synthetase 1 0.301398
ALPL alkaline phosphatase, liver/bone/kidney 0.301398
ALPP alkaline phosphatase, placental 0.300679
MYH10 myosin, heavy chain 10, non-muscle 0.30032
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.285316
GPX3 glutathione peroxidase 3 0.284607
SMAD9 SMAD family member 9 0.28107
HES3 hes family bHLH transcription factor 3 0.278955
ADNP activity-dependent neuroprotector homeobox 0.278955
RBP1 retinol binding protein 1, cellular 0.2779
IRX3 iroquois homeobox 3 0.2779
STIP1 stress-induced phosphoprotein 1 0.275444
FOS FBJ murine osteosarcoma viral oncogene homolog 0.275094
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.272649
CLDN6 claudin 6 0.271256
HLA-B major histocompatibility complex, class I, B 0.270909
FOSL1 FOS-like antigen 1 0.270561
OCRL oculocerebrorenal syndrome of Lowe 0.268482
LDB1 LIM domain binding 1 0.268137
KMT2B lysine (K)-specific methyltransferase 2B 0.267446
SLC22A18 solute carrier family 22, member 18 0.267102
ELSPBP1 epididymal sperm binding protein 1 0.264353
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.263669
PAX6 paired box 6 0.260606
MED1 mediator complex subunit 1 0.260267
PTPRB protein tyrosine phosphatase, receptor type, B 0.259591
SIX6 SIX homeobox 6 0.256234
SEBOX SEBOX homeobox 0.253248
BMP8B bone morphogenetic protein 8b 0.251606
FGF17 fibroblast growth factor 17 0.250953
GDF11 growth differentiation factor 11 0.250953
JUP junction plakoglobin 0.250301
ELF5 E74-like factor 5 (ets domain transcription factor) 0.248683
MEF2C myocyte enhancer factor 2C 0.24804
CBX5 chromobox homolog 5 0.247079
PGK1 phosphoglycerate kinase 1 0.246442
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.246442
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.245807
HES6 hes family bHLH transcription factor 6 0.243918
MDK midkine (neurite growth-promoting factor 2) 0.243605
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.243294
HOXA13 homeobox A13 0.242983
HLA-A major histocompatibility complex, class I, A 0.242672
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.242054
DVL2 dishevelled segment polarity protein 2 0.23961
YY1 YY1 transcription factor 0.237216
CASC5 cancer susceptibility candidate 5 0.235167
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.235167
MEOX2 mesenchyme homeobox 2 0.23459
ERF Ets2 repressor factor 0.23459
NFYA nuclear transcription factor Y, alpha 0.233731
PAX1 paired box 1 0.232039
TPBG trophoblast glycoprotein 0.23176
GATA5 GATA binding protein 5 0.23011
HOXA11 homeobox A11 0.226667
APOA1 apolipoprotein A-I 0.226155
ARHGAP18 Rho GTPase activating protein 18 0.226155
PAX2 paired box 2 0.2259
SPAST spastin 0.225647
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.225395
WNT5A wingless-type MMTV integration site family, member 5A 0.221521
DLK1 delta-like 1 homolog (Drosophila) 0.218613
PLAU plasminogen activator, urokinase 0.217554
EPAS1 endothelial PAS domain protein 1 0.217139
STARD13 StAR-related lipid transfer (START) domain containing 13 0.215147
PRSS8 protease, serine, 8 0.214765
FZD4 frizzled class receptor 4 0.21365
VANGL2 VANGL planar cell polarity protein 2 0.213291
ACSS2 acyl-CoA synthetase short-chain family member 2 0.212586
SET SET nuclear proto-oncogene 0.188066
EFNA2 ephrin-A2 0.187937
WNT6 wingless-type MMTV integration site family, member 6 0.187791
RPL13A ribosomal protein L13a 0.187708
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.187625
FOXJ1 forkhead box J1 0.18683
TTPA tocopherol (alpha) transfer protein 0.18643
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.186281
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.186262
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.185899
GBX2 gastrulation brain homeobox 2 0.18586
ISL1 ISL LIM homeobox 1 0.185763
COL4A1 collagen, type IV, alpha 1 0.185684
ACVR1 activin A receptor, type I 0.185505
HOXA5 homeobox A5 0.185485
WNT7B wingless-type MMTV integration site family, member 7B 0.185323
TFG TRK-fused gene 0.184675
FLCN folliculin 0.18461
NEUROD1 neuronal differentiation 1 0.184214
LGALS7 lectin, galactoside-binding, soluble, 7 0.184169
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.183965
VDAC1 voltage-dependent anion channel 1 0.183873
PTF1A pancreas specific transcription factor, 1a 0.183758
NMS neuromedin S 0.18343
FGF5 fibroblast growth factor 5 0.183334
PDX1 pancreatic and duodenal homeobox 1 0.18314
SOX1 SRY (sex determining region Y)-box 1 0.18292
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.182618
KRT19 keratin 19, type I 0.181941
TJP1 tight junction protein 1 0.181941
PLAUR plasminogen activator, urokinase receptor 0.181111
SOX3 SRY (sex determining region Y)-box 3 0.181083
PAX4 paired box 4 0.180498
PLAT plasminogen activator, tissue 0.180226
SALL4 spalt-like transcription factor 4 0.180226
KRT18 keratin 18, type I 0.179855
EN2 engrailed homeobox 2 0.179697