extracellular vesicular exosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. (Gene Ontology, GO_0070062)
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Genes

333 proteins co-occuring with the extracellular vesicular exosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 2.41832
EXOSC2 exosome component 2 2.30104
CD63 CD63 molecule 1.94042
EXOSC4 exosome component 4 1.78583
CD9 CD9 molecule 1.71808
CD81 CD81 molecule 1.65995
EXOSC5 exosome component 5 1.56674
EXOSC8 exosome component 8 1.53952
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.51638
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 1.43669
EXOSC3 exosome component 3 1.42092
MFGE8 milk fat globule-EGF factor 8 protein 1.40466
TSG101 tumor susceptibility 101 1.3752
MIR21 microRNA 21 1.35923
ZC3HAV1 zinc finger CCCH-type, antiviral 1 1.35156
DIS3L DIS3 like exosome 3'-5' exoribonuclease 1.25917
STEAP3 STEAP family member 3, metalloreductase 1.25443
XRN1 5'-3' exoribonuclease 1 1.21635
ZCCHC7 zinc finger, CCHC domain containing 7 1.16184
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 1.14085
KHSRP KH-type splicing regulatory protein 1.1296
PNPT1 polyribonucleotide nucleotidyltransferase 1 1.12807
CD4 CD4 molecule 1.09086
AGO2 argonaute RISC catalytic component 2 1.07005
HSPA4 heat shock 70kDa protein 4 1.06195
HLA-B major histocompatibility complex, class I, B 1.05337
EXOSC10 exosome component 10 1.05136
PARN poly(A)-specific ribonuclease 1.03879
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.03529
WDR61 WD repeat domain 61 1.02231
RAB27B RAB27B, member RAS oncogene family 0.994652
PAPD7 PAP associated domain containing 7 0.984393
CD86 CD86 molecule 0.982932
MIR17 microRNA 17 0.966474
EXOSC9 exosome component 9 0.951619
MIR210 microRNA 210 0.920918
TTC37 tetratricopeptide repeat domain 37 0.919982
MIR223 microRNA 223 0.90321
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.898572
AQP2 aquaporin 2 (collecting duct) 0.897183
CD80 CD80 molecule 0.887936
RAB27A RAB27A, member RAS oncogene family 0.878712
FASLG Fas ligand (TNF superfamily, member 6) 0.871806
TFRC transferrin receptor 0.86169
TSPAN8 tetraspanin 8 0.86169
CD24 CD24 molecule 0.858473
MIR192 microRNA 192 0.83781
RBM7 RNA binding motif protein 7 0.811652
LRRC24 leucine rich repeat containing 24 0.807524
CHMP4C charged multivesicular body protein 4C 0.800645
FLOT1 flotillin 1 0.796062
ICAM1 intercellular adhesion molecule 1 0.795145
ADAM10 ADAM metallopeptidase domain 10 0.79148
XRN2 5'-3' exoribonuclease 2 0.772732
LSM1 LSM1, U6 small nuclear RNA associated 0.734666
RHBDD1 rhomboid domain containing 1 0.734666
CNOT10 CCR4-NOT transcription complex, subunit 10 0.72258
PRNP prion protein 0.717236
MICA MHC class I polypeptide-related sequence A 0.715458
DCPS decapping enzyme, scavenger 0.709693
PAPD5 PAP associated domain containing 5 0.703949
NRD1 nardilysin (N-arginine dibasic convertase) 0.699103
MIR221 microRNA 221 0.692516
C1D C1D nuclear receptor corepressor 0.692516
TXNDC16 thioredoxin domain containing 16 0.687264
CD40 CD40 molecule, TNF receptor superfamily member 5 0.680719
ULBP1 UL16 binding protein 1 0.67463
L1CAM L1 cell adhesion molecule 0.673762
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.662072
MIR222 microRNA 222 0.650439
MIR22 microRNA 22 0.650439
GTPBP1 GTP binding protein 1 0.641001
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.635868
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.63544
MIR19A microRNA 19a 0.629039
EFNA3 ephrin-A3 0.616709
FOXP3 forkhead box P3 0.612895
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 0.612895
MPHOSPH6 M-phase phosphoprotein 6 0.607395
RNASEH2A ribonuclease H2, subunit A 0.607395
JAK3 Janus kinase 3 0.605284
ANXA2 annexin A2 0.604862
PROM1 prominin 1 0.601487
TMPRSS2 transmembrane protease, serine 2 0.588456
LOC102724852 uncharacterized LOC102724852 0.587199
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.582594
MIR100 microRNA 100 0.578833
PABPN1 poly(A) binding protein, nuclear 1 0.562187
DCP2 decapping mRNA 2 0.558457
CD82 CD82 molecule 0.5568
MYD88 myeloid differentiation primary response 88 0.54606
DPP4 dipeptidyl-peptidase 4 0.54606
FLOT2 flotillin 2 0.544823
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.541117
GLIPR1L1 GLI pathogenesis-related 1 like 1 0.535772
ZCCHC8 zinc finger, CCHC domain containing 8 0.532078
TSPAN3 tetraspanin 3 0.527569
TBC1D10A TBC1 domain family, member 10A 0.52675
MIR203A microRNA 203a 0.526341
HSPA8 heat shock 70kDa protein 8 0.521841
MIR146A microRNA 146a 0.517756
LGALS9 lectin, galactoside-binding, soluble, 9 0.511233
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.506757
DICER1 dicer 1, ribonuclease type III 0.500258
HEPACAM hepatic and glial cell adhesion molecule 0.499447
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.495395
UMOD uromodulin 0.490539
NDFIP1 Nedd4 family interacting protein 1 0.485289
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.482064
MIR214 microRNA 214 0.478843
CSDE1 cold shock domain containing E1, RNA-binding 0.478843
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.474822
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.471609
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.463997
ZC3H18 zinc finger CCCH-type containing 18 0.461998
MIR145 microRNA 145 0.459203
MUC13 mucin 13, cell surface associated 0.457606
IGSF8 immunoglobulin superfamily, member 8 0.455613
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.453621
BAG6 BCL2-associated athanogene 6 0.446862
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.446069
ADAM17 ADAM metallopeptidase domain 17 0.446069
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.43617
EGFR epidermal growth factor receptor 0.434985
TNF tumor necrosis factor 0.432618
TLR3 toll-like receptor 3 0.429072
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.427891
PABPC1 poly(A) binding protein, cytoplasmic 1 0.426711
LAMP2 lysosomal-associated membrane protein 2 0.426318
ARRDC1 arrestin domain containing 1 0.425531
SETX senataxin 0.425531
PCF11 PCF11 cleavage and polyadenylation factor subunit 0.425138
MUC16 mucin 16, cell surface associated 0.424745
MICB MHC class I polypeptide-related sequence B 0.423174
ZNF185 zinc finger protein 185 (LIM domain) 0.42082
MIR130B microRNA 130b 0.417685
SDCBP syndecan binding protein (syntenin) 0.415728
TLR7 toll-like receptor 7 0.413382
PDCD6IP programmed cell death 6 interacting protein 0.411039
CD40LG CD40 ligand 0.409479
ANXA5 annexin A5 0.408309
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 0.404415
RAB5B RAB5B, member RAS oncogene family 0.403637
CD276 CD276 molecule 0.400916
LGALS3 lectin, galactoside-binding, soluble, 3 0.399363
LGALS13 lectin, galactoside-binding, soluble, 13 0.398199
LAMP1 lysosomal-associated membrane protein 1 0.397811
MIR197 microRNA 197 0.397423
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.395485
VASN vasorin 0.395485
TNIK TRAF2 and NCK interacting kinase 0.39471
WNT5A wingless-type MMTV integration site family, member 5A 0.393936
KLK3 kallikrein-related peptidase 3 0.393162
TPBG trophoblast glycoprotein 0.392775
ELAVL1 ELAV like RNA binding protein 1 0.392001
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.388523
AQP11 aquaporin 11 0.383895
NLRP8 NLR family, pyrin domain containing 8 0.383124
CAV1 caveolin 1, caveolae protein, 22kDa 0.382354
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.379276
ZNF512 zinc finger protein 512 0.375818
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.368919
CST3 cystatin C 0.367771
ARMC10 armadillo repeat containing 10 0.367388
TLR4 toll-like receptor 4 0.366623
TUG1 taurine up-regulated 1 (non-protein coding) 0.36204
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.359752
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.357467
PTEN phosphatase and tensin homolog 0.355563
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 0.355563
MIR26B microRNA 26b 0.354422
AICDA activation-induced cytidine deaminase 0.352142
TMX2 thioredoxin-related transmembrane protein 2 0.352142
CD59 CD59 molecule, complement regulatory protein 0.348346
PRSS8 protease, serine, 8 0.344178
TBX1 T-box 1 0.340017
AHSG alpha-2-HS-glycoprotein 0.340017
MIR98 microRNA 98 0.339261
ERBB2 erb-b2 receptor tyrosine kinase 2 0.339261
MME membrane metallo-endopeptidase 0.338884
CIITA class II, major histocompatibility complex, transactivator 0.338128
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.338128
ZC3H14 zinc finger CCCH-type containing 14 0.336619
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.335864
TMEM30A transmembrane protein 30A 0.335487
TLR2 toll-like receptor 2 0.334356
ZFP36 ZFP36 ring finger protein 0.331719
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.329461
EPCAM epithelial cell adhesion molecule 0.325702
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.325327
SNX25 sorting nexin 25 0.32345
HLA-DMA major histocompatibility complex, class II, DM alpha 0.32345
LGI3 leucine-rich repeat LGI family, member 3 0.321575
CD44 CD44 molecule (Indian blood group) 0.320451
FADS3 fatty acid desaturase 3 0.318579
TP53 tumor protein p53 0.31783
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.31596
WNT3A wingless-type MMTV integration site family, member 3A 0.315212
TSPO translocator protein (18kDa) 0.314465
GLIPR2 GLI pathogenesis-related 2 0.314465
URM1 ubiquitin related modifier 1 0.312597
VRK1 vaccinia related kinase 1 0.312224
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.309986
TRMT61A tRNA methyltransferase 61A 0.308867
MYRIP myosin VIIA and Rab interacting protein 0.308494
ADI1 acireductone dioxygenase 1 0.305888
CD69 CD69 molecule 0.304771
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.302912
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.301054
AQP6 aquaporin 6, kidney specific 0.300682
QTRT1 queuine tRNA-ribosyltransferase 1 0.299569
HLA-G major histocompatibility complex, class I, G 0.298455
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.296972
GIP gastric inhibitory polypeptide 0.292527
LYPD3 LY6/PLAUR domain containing 3 0.292527
TNRC6B trinucleotide repeat containing 6B 0.289938
PODXL podocalyxin-like 0.289569
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.287352
ZNF692 zinc finger protein 692 0.285138
MIRLET7D microRNA let-7d 0.283663
EXPH5 exophilin 5 0.282926
VTA1 vesicle (multivesicular body) trafficking 1 0.282189
CD19 CD19 molecule 0.280716
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.27998
CARD17 caspase recruitment domain family, member 17 0.278509
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.278141
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.276671
CD5L CD5 molecule-like 0.276304
MUC1 mucin 1, cell surface associated 0.274835
SLBP stem-loop binding protein 0.274835
MORF4 mortality factor 4 (pseudogene) 0.274468
SNX31 sorting nexin 31 0.274101
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.272633
CANX calnexin 0.269701
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.268603
DGKA diacylglycerol kinase, alpha 80kDa 0.268603
ATP13A2 ATPase type 13A2 0.266774
GRHL3 grainyhead-like 3 (Drosophila) 0.266408
CD37 CD37 molecule 0.266042
RPP14 ribonuclease P/MRP 14kDa subunit 0.265677
HLA-A major histocompatibility complex, class I, A 0.265311
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.261296
F3 coagulation factor III (thromboplastin, tissue factor) 0.260931
NLRP3 NLR family, pyrin domain containing 3 0.259837
MIR133B microRNA 133b 0.259473
VEGFA vascular endothelial growth factor A 0.253653
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.253291
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.249302
CXCL12 chemokine (C-X-C motif) ligand 12 0.24894
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.246046
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.243879
CD34 CD34 molecule 0.242797
TLR8 toll-like receptor 8 0.242437
PRF1 perforin 1 (pore forming protein) 0.239916
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.238837
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.238478
MIR27B microRNA 27b 0.238478
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.238119
USB1 U6 snRNA biogenesis 1 0.237401
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.235249
RBMXL1 RNA binding motif protein, X-linked-like 1 0.233817
ERVW-1 endogenous retrovirus group W, member 1 0.232744
S100A9 S100 calcium binding protein A9 0.227752
MAPK4 mitogen-activated protein kinase 4 0.227752
AQP1 aquaporin 1 (Colton blood group) 0.227041
CNOT6 CCR4-NOT transcription complex, subunit 6 0.225622
AREG amphiregulin 0.22279
IFI16 interferon, gamma-inducible protein 16 0.222083
AHRR aryl-hydrocarbon receptor repressor 0.221025
MIR183 microRNA 183 0.218563
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.218212
SGMS2 sphingomyelin synthase 2 0.217511
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.21646
RASA3 RAS p21 protein activator 3 0.216111
CXCL11 chemokine (C-X-C motif) ligand 11 0.216111
IFNA17 interferon, alpha 17 0.215412
CD83 CD83 molecule 0.213669
IDE insulin-degrading enzyme 0.213669
STC2 stanniocalcin 2 0.212627
GCOM1 GRINL1A complex locus 1 0.212627
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.209169
ULBP3 UL16 binding protein 3 0.207451
AQP7 aquaporin 7 0.206423
ERI1 exoribonuclease 1 0.206082
MIR107 microRNA 107 0.205399
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.204718
APP amyloid beta (A4) precursor protein 0.203699
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.202684
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.201672
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.200999
CD247 CD247 molecule 0.200328
DENND1A DENN/MADD domain containing 1A 0.197993
WDR92 WD repeat domain 92 0.196999
F8 coagulation factor VIII, procoagulant component 0.196669
NXF1 nuclear RNA export factor 1 0.196669
DLL4 delta-like 4 (Drosophila) 0.194045
GFM2 G elongation factor, mitochondrial 2 0.192746
IK IK cytokine, down-regulator of HLA II 0.192423
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.1921
MMP1 matrix metallopeptidase 1 0.191456
WNT11 wingless-type MMTV integration site family, member 11 0.190175
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.189857
RBMX RNA binding motif protein, X-linked 0.188905
SESN1 sestrin 1 0.188274
TGFB1 transforming growth factor, beta 1 0.187333
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.186087
RAI1 retinoic acid induced 1 0.185469
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.183328
LCN2 lipocalin 2 0.182122
ITSN2 intersectin 2 0.181823
DAB2IP DAB2 interacting protein 0.180045
ANXA1 annexin A1 0.175745
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.174635
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.173273
SNAPIN SNAP-associated protein 0.172468
TET3 tet methylcytosine dioxygenase 3 0.170371
DNAH8 dynein, axonemal, heavy chain 8 0.170114
TNNT1 troponin T type 1 (skeletal, slow) 0.169604
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.169604
DEK DEK proto-oncogene 0.16935
ANGPTL7 angiopoietin-like 7 0.168847
HRAS Harvey rat sarcoma viral oncogene homolog 0.168349
ERVFRD-1 endogenous retrovirus group FRD, member 1 0.168349
EFNA4 ephrin-A4 0.168101
LTV1 LTV1 ribosome biogenesis factor 0.165463
ERAP1 endoplasmic reticulum aminopeptidase 1 0.165
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.164542
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.164315
RAP2A RAP2A, member of RAS oncogene family 0.16298
NCAM1 neural cell adhesion molecule 1 0.161484
BIRC5 baculoviral IAP repeat containing 5 0.161068
HLA-C major histocompatibility complex, class I, C 0.158315
BACE1 beta-site APP-cleaving enzyme 1 0.157039