exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. (Gene Ontology, GO_0016796)
External Link http://amigo.geneontology.org/amigo/term/GO:0016796
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Genes

43 genes performing the exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APTX aprataxin
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT2 CCR4-NOT transcription complex, subunit 2
CNOT6 CCR4-NOT transcription complex, subunit 6
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNOT7 CCR4-NOT transcription complex, subunit 7
CNOT8 CCR4-NOT transcription complex, subunit 8
DCLRE1A DNA cross-link repair 1A
DCP2 decapping mRNA 2
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
ERI1 exoribonuclease 1
ERI2 ERI1 exoribonuclease family member 2
ERI3 ERI1 exoribonuclease family member 3
EXO1 exonuclease 1
EXO5 exonuclease 5
EXOSC2 exosome component 2
EXOSC3 exosome component 3
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC7 exosome component 7
EXOSC9 exosome component 9
FEN1 flap structure-specific endonuclease 1
ISG20 interferon stimulated exonuclease gene 20kDa
MEIOB meiosis specific with OB domains
MGME1 mitochondrial genome maintenance exonuclease 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAN3 PAN3 poly(A) specific ribonuclease subunit
PARN poly(A)-specific ribonuclease
PDE12 phosphodiesterase 12
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
RAD1 RAD1 checkpoint DNA exonuclease
RAD9A RAD9 homolog A (S. pombe)
REXO2 RNA exonuclease 2
TREX1 three prime repair exonuclease 1
TREX2 three prime repair exonuclease 2
USB1 U6 snRNA biogenesis 1
XRN2 5'-3' exoribonuclease 2