ewing's family tumor cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The Ewing's family of tumors includes Ewing's tumor of bone, extraosseus Ewing's sarcoma, primitive neuroectodermal tumors, and Askin's tumor. All of these tumors are derived from the same primordial stem cell, the primitive nerve cell. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004255)
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Genes

263 proteins co-occuring with the tissue ewing's family tumor cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 3.12909
FLI1 Fli-1 proto-oncogene, ETS transcription factor 2.84282
ZNF43 zinc finger protein 43 1.4589
CD99 CD99 molecule 1.408
SH2D1B SH2 domain containing 1B 1.3878
C21ORF33 chromosome 21 open reading frame 33 1.27695
IGF1R insulin-like growth factor 1 receptor 1.19223
LIPI lipase, member I 1.09518
APOL6 apolipoprotein L, 6 1.07706
ZNF253 zinc finger protein 253 1.06074
DRAM1 DNA-damage regulated autophagy modulator 1 1.0603
ZMYM3 zinc finger, MYM-type 3 1.02644
ETV1 ets variant 1 1.01375
ETV4 ets variant 4 0.871061
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.868107
ABHD6 abhydrolase domain containing 6 0.860942
C8A complement component 8, alpha polypeptide 0.849585
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.816486
B3GAT1 beta-1,3-glucuronyltransferase 1 0.803961
EYA3 EYA transcriptional coactivator and phosphatase 3 0.803961
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.798125
TP53 tumor protein p53 0.79146
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.778986
CENPV centromere protein V 0.77857
SH2D4B SH2 domain containing 4B 0.744214
STOML2 stomatin (EPB72)-like 2 0.73803
AMELY amelogenin, Y-linked 0.70968
AMELX amelogenin, X-linked 0.699853
STK24 serine/threonine kinase 24 0.696581
GSTM4 glutathione S-transferase mu 4 0.689634
PCDH7 protocadherin 7 0.689226
ENO2 enolase 2 (gamma, neuronal) 0.679025
PDGFC platelet derived growth factor C 0.672913
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.668436
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.665995
IGF1 insulin-like growth factor 1 (somatomedin C) 0.632335
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.631527
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.62991
STAG2 stromal antigen 2 0.624658
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.621831
REST RE1-silencing transcription factor 0.617796
AMBN ameloblastin (enamel matrix protein) 0.60893
BCOR BCL6 corepressor 0.594451
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.580818
CD226 CD226 molecule 0.575216
XAGE1E X antigen family, member 1E 0.575216
XAGE1B X antigen family, member 1B 0.565232
TNK2 tyrosine kinase, non-receptor, 2 0.558856
SLAMF6 SLAM family member 6 0.539
PARP1 poly (ADP-ribose) polymerase 1 0.529508
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.527139
MDM4 MDM4, p53 regulator 0.523194
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.505887
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.497266
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.493745
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.481648
LAMB3 laminin, beta 3 0.478923
STK26 serine/threonine protein kinase 26 0.472315
PIR pirin (iron-binding nuclear protein) 0.467273
ITGA6 integrin, alpha 6 0.435672
HINT1 histidine triad nucleotide binding protein 1 0.43146
PROM1 prominin 1 0.430695
HDGF hepatoma-derived growth factor 0.421529
IGFBP3 insulin-like growth factor binding protein 3 0.407453
ZNF629 zinc finger protein 629 0.405555
ZNF763 zinc finger protein 763 0.405555
ZNF501 zinc finger protein 501 0.405555
ZNF569 zinc finger protein 569 0.402144
MIR31 microRNA 31 0.396465
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.391931
JUN jun proto-oncogene 0.389289
ZNF44 zinc finger protein 44 0.388912
CCND1 cyclin D1 0.387781
CD248 CD248 molecule, endosialin 0.383637
APLP2 amyloid beta (A4) precursor-like protein 2 0.383637
REEP5 receptor accessory protein 5 0.381003
SIM1 single-minded family bHLH transcription factor 1 0.380251
LONP1 lon peptidase 1, mitochondrial 0.375368
ZNF436 zinc finger protein 436 0.366754
BCL6B B-cell CLL/lymphoma 6, member B 0.36526
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.363393
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.358174
WRN Werner syndrome, RecQ helicase-like 0.352598
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.352227
PBK PDZ binding kinase 0.34926
PRAME preferentially expressed antigen in melanoma 0.348519
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.347408
ZYX zyxin 0.344818
BCR breakpoint cluster region 0.344079
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.344079
CCKAR cholecystokinin A receptor 0.341863
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.335968
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.327896
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.324605
DGCR8 DGCR8 microprocessor complex subunit 0.324605
CCKBR cholecystokinin B receptor 0.322414
CAV1 caveolin 1, caveolae protein, 22kDa 0.32132
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.320956
EDNRA endothelin receptor type A 0.318042
PDGFB platelet-derived growth factor beta polypeptide 0.307167
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.303919
IL15 interleukin 15 0.302118
MECOM MDS1 and EVI1 complex locus 0.301758
NUMBL numb homolog (Drosophila)-like 0.30032
KLF10 Kruppel-like factor 10 0.291008
GLI1 GLI family zinc finger 1 0.289939
IFITM2 interferon induced transmembrane protein 2 0.28213
KDM1A lysine (K)-specific demethylase 1A 0.277197
POU4F1 POU class 4 homeobox 1 0.276145
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.276145
PRIMA1 proline rich membrane anchor 1 0.265381
BECN1 beclin 1, autophagy related 0.261284
WEE1 WEE1 G2 checkpoint kinase 0.256902
CCK cholecystokinin 0.246442
MIR145 microRNA 145 0.245807
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.244232
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.235457
CA6 carbonic anhydrase VI 0.23459
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.229299
PLD2 phospholipase D2 0.228497
CD177 CD177 molecule 0.226155
FUS FUS RNA binding protein 0.21883
CXCL12 chemokine (C-X-C motif) ligand 12 0.218186
AURKA aurora kinase A 0.21673
GYG2 glycogenin 2 0.215681
ZEB2 zinc finger E-box binding homeobox 2 0.214388
PTCH1 patched 1 0.214388
LOX lysyl oxidase 0.213833
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.213291
FES FES proto-oncogene, tyrosine kinase 0.213112
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.212936
GYG1 glycogenin 1 0.194177
SFRP5 secreted frizzled-related protein 5 0.193732
CLSPN claspin 0.193279
LYN LYN proto-oncogene, Src family tyrosine kinase 0.192147
SFRP1 secreted frizzled-related protein 1 0.191234
MIR130B microRNA 130b 0.189859
SFRP2 secreted frizzled-related protein 2 0.188864
LDB3 LIM domain binding 3 0.188706
WNT5A wingless-type MMTV integration site family, member 5A 0.187307
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.18674
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.186471
COL11A2 collagen, type XI, alpha 2 0.186443
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.185419
FGFR1 fibroblast growth factor receptor 1 0.185159
MRPS7 mitochondrial ribosomal protein S7 0.184797
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.184225
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.183376
MDK midkine (neurite growth-promoting factor 2) 0.182368
ZNF77 zinc finger protein 77 0.181147
GLI2 GLI family zinc finger 2 0.180609
GLYCTK glycerate kinase 0.179064
FAM84B family with sequence similarity 84, member B 0.178374
KCMF1 potassium channel modulatory factor 1 0.178189
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.17601
TAPBP TAP binding protein (tapasin) 0.175989
CDK4 cyclin-dependent kinase 4 0.175875
MIR186 microRNA 186 0.173611
BIRC5 baculoviral IAP repeat containing 5 0.17253
KLK4 kallikrein-related peptidase 4 0.172159
PYY peptide YY 0.170218
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.168985
CFLAR CASP8 and FADD-like apoptosis regulator 0.16741
TRIB1 tribbles pseudokinase 1 0.165959
KIF1A kinesin family member 1A 0.164007
FER fer (fps/fes related) tyrosine kinase 0.163949
AXL AXL receptor tyrosine kinase 0.163249
VIPR2 vasoactive intestinal peptide receptor 2 0.162284
SCG2 secretogranin II 0.161262
CIITA class II, major histocompatibility complex, transactivator 0.161157
KIF1B kinesin family member 1B 0.16103
NGF nerve growth factor (beta polypeptide) 0.16018
FZD3 frizzled class receptor 3 0.156694
KMT2A lysine (K)-specific methyltransferase 2A 0.156545
FTL ferritin, light polypeptide 0.155487
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.155232
NPY neuropeptide Y 0.15513
FTH1 ferritin, heavy polypeptide 1 0.154999
HPSE heparanase 0.154657
PCCA propionyl CoA carboxylase, alpha polypeptide 0.154
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.152917
DVL3 dishevelled segment polarity protein 3 0.151602
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.151373
MTSS1 metastasis suppressor 1 0.151086
CGB7 chorionic gonadotropin, beta polypeptide 7 0.147863
CGB5 chorionic gonadotropin, beta polypeptide 5 0.14755
TSPO translocator protein (18kDa) 0.147175
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.146704
DMBT1 deleted in malignant brain tumors 1 0.146382
CGB chorionic gonadotropin, beta polypeptide 0.146222
CGB8 chorionic gonadotropin, beta polypeptide 8 0.146125
C5 complement component 5 0.145515
GLB1 galactosidase, beta 1 0.145418
ULBP1 UL16 binding protein 1 0.144955
CA2 carbonic anhydrase II 0.144856
DVL2 dishevelled segment polarity protein 2 0.143081
NF1 neurofibromin 1 0.141979
VEGFB vascular endothelial growth factor B 0.141
MTAP methylthioadenosine phosphorylase 0.139167
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.139093
WNT2B wingless-type MMTV integration site family, member 2B 0.138801
CHGB chromogranin B 0.137954
JAK1 Janus kinase 1 0.13649
DCXR dicarbonyl/L-xylulose reductase 0.136183
MICB MHC class I polypeptide-related sequence B 0.135876
FGFR2 fibroblast growth factor receptor 2 0.135685
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.13417
VIPR1 vasoactive intestinal peptide receptor 1 0.133739
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.133266
MAP1B microtubule-associated protein 1B 0.132464
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.132383
WNT3A wingless-type MMTV integration site family, member 3A 0.132063
DVL1 dishevelled segment polarity protein 1 0.130923
NEFM neurofilament, medium polypeptide 0.129438
GRP gastrin-releasing peptide 0.12902
FHIT fragile histidine triad 0.127458
CHGA chromogranin A 0.127075
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.126174
WNT10B wingless-type MMTV integration site family, member 10B 0.125826
WNT11 wingless-type MMTV integration site family, member 11 0.125435
TNIP1 TNFAIP3 interacting protein 1 0.124872
NEFH neurofilament, heavy polypeptide 0.124609
LRP6 low density lipoprotein receptor-related protein 6 0.123769
SHH sonic hedgehog 0.12368
FZD1 frizzled class receptor 1 0.122841
PIDD1 p53-induced death domain protein 1 0.122256
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.122031
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.121986
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.121851
S100A4 S100 calcium binding protein A4 0.121177
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.120402
PI3 peptidase inhibitor 3, skin-derived 0.119078
PLA2G1B phospholipase A2, group IB (pancreas) 0.117777
NRG1 neuregulin 1 0.117128
CDKN2A cyclin-dependent kinase inhibitor 2A 0.116656
PROS1 protein S (alpha) 0.115996
ANXA5 annexin A5 0.115996
FGF2 fibroblast growth factor 2 (basic) 0.114623
FADD Fas (TNFRSF6)-associated via death domain 0.112562
CDC25A cell division cycle 25A 0.112513
IGF2 insulin-like growth factor 2 0.11116
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.110327
RB1 retinoblastoma 1 0.110131
OXA1L oxidase (cytochrome c) assembly 1-like 0.10974
CADM1 cell adhesion molecule 1 0.108163
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.107025
MAP4 microtubule-associated protein 4 0.106574
VCAN versican 0.106324
COL1A1 collagen, type I, alpha 1 0.105575
MICA MHC class I polypeptide-related sequence A 0.104673
NOTCH2NL notch 2 N-terminal like 0.104572
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.10442
NOTCH2 notch 2 0.104218
HRAS Harvey rat sarcoma viral oncogene homolog 0.104016
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.10311
MCF2 MCF.2 cell line derived transforming sequence 0.102908
IRS1 insulin receptor substrate 1 0.102704
FOS FBJ murine osteosarcoma viral oncogene homolog 0.102093
NKX2-2 NK2 homeobox 2 0.101636
TGFB3 transforming growth factor, beta 3 0.101433
PDPN podoplanin 0.101179
YBX1 Y box binding protein 1 0.100516
TERT telomerase reverse transcriptase 0.100413