eukaryotic translation initiation factor 4f complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome. (Gene Ontology, GO_0016281)
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77 proteins co-occuring with the eukaryotic translation initiation factor 4f complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EIF4E eukaryotic translation initiation factor 4E 3.48218
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 3.37949
EIF4B eukaryotic translation initiation factor 4B 2.79099
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.48466
PABPC1 poly(A) binding protein, cytoplasmic 1 1.79906
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.79442
NGDN neuroguidin, EIF4E binding protein 1.78517
MKNK1 MAP kinase interacting serine/threonine kinase 1 1.59257
EIF4H eukaryotic translation initiation factor 4H 1.5656
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.5367
EIF4A2 eukaryotic translation initiation factor 4A2 1.49831
RPS6 ribosomal protein S6 1.42993
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.34665
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.27664
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 1.16081
PAIP2 poly(A) binding protein interacting protein 2 1.1603
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.099
EIF4E3 eukaryotic translation initiation factor 4E family member 3 1.04582
EIF5 eukaryotic translation initiation factor 5 0.952096
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.943059
PAIP1 poly(A) binding protein interacting protein 1 0.926543
EEF2 eukaryotic translation elongation factor 2 0.923259
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.881016
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.840564
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 0.82037
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.801104
PAIP2B poly(A) binding protein interacting protein 2B 0.74322
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.735115
RBM38 RNA binding motif protein 38 0.71457
EIF5B eukaryotic translation initiation factor 5B 0.66726
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.620529
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.604017
EIF4A1 eukaryotic translation initiation factor 4A1 0.589714
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.585942
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.585523
EIF3E eukaryotic translation initiation factor 3, subunit E 0.576747
DDIT4 DNA-damage-inducible transcript 4 0.561358
INS insulin 0.554318
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.503099
SSB Sjogren syndrome antigen B (autoantigen La) 0.49661
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.487711
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.485289
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 0.48005
NCBP2 nuclear cap binding protein subunit 2, 20kDa 0.47844
F11 coagulation factor XI 0.47844
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.463997
CCND1 cyclin D1 0.458803
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.454418
EEF2K eukaryotic elongation factor 2 kinase 0.447656
EIF4A3 eukaryotic translation initiation factor 4A3 0.434985
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.423174
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.400916
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.361659
LGTN ligatin 0.35899
TRIM22 tripartite motif containing 22 0.353662
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.34645
SH2D3C SH2 domain containing 3C 0.344935
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.332472
FAM155B family with sequence similarity 155, member B 0.328708
CSN1S1 casein alpha s1 0.326453
EIF6 eukaryotic translation initiation factor 6 0.308867
RPTOR regulatory associated protein of MTOR, complex 1 0.281085
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.250751
HSPA4 heat shock 70kDa protein 4 0.24894
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.24424
EIF3C eukaryotic translation initiation factor 3, subunit C 0.234891
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.216111
GEMIN5 gem (nuclear organelle) associated protein 5 0.213322
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.211587
IGF1 insulin-like growth factor 1 (somatomedin C) 0.206423
MRPL13 mitochondrial ribosomal protein L13 0.195353
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.18702
VEGFA vascular endothelial growth factor A 0.178011
BMF Bcl2 modifying factor 0.165231
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.158882
PRKCA protein kinase C, alpha 0.158129
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.157397