eukaryotic translation initiation factor 3 complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. (Gene Ontology, GO_0005852)
External Link http://amigo.geneontology.org/amigo/term/GO:0005852
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Genes

16 proteins localized to the eukaryotic translation initiation factor 3 complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
COPS5 COP9 signalosome subunit 5
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M