eukaryotic translation initiation factor 3 complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. (Gene Ontology, GO_0005852)
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15 proteins localized to the eukaryotic translation initiation factor 3 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EIF3F eukaryotic translation initiation factor 3, subunit F 0.663342
EIF3E eukaryotic translation initiation factor 3, subunit E 0.663342
EIF3B eukaryotic translation initiation factor 3, subunit B 0.663342
EIF3A eukaryotic translation initiation factor 3, subunit A 0.663342
EIF3M eukaryotic translation initiation factor 3, subunit M 0.663342
EIF3L eukaryotic translation initiation factor 3, subunit L 0.663342
EIF3K eukaryotic translation initiation factor 3, subunit K 0.663342
EIF3J eukaryotic translation initiation factor 3, subunit J 0.663342
EIF3I eukaryotic translation initiation factor 3, subunit I 0.663342
EIF3H eukaryotic translation initiation factor 3, subunit H 0.663342
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.663342
EIF3G eukaryotic translation initiation factor 3, subunit G 0.663342
EIF3D eukaryotic translation initiation factor 3, subunit D 0.663342
EIF3C eukaryotic translation initiation factor 3, subunit C 0.663342
COPS5 COP9 signalosome subunit 5 0.237908