eukaryotic translation initiation factor 2b complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. (Gene Ontology, GO_0005851)
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85 proteins co-occuring with the eukaryotic translation initiation factor 2b complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 3.26634
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.69746
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 2.48726
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.47515
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.74574
EIF4E eukaryotic translation initiation factor 4E 1.74193
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.72619
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.68787
EIF5 eukaryotic translation initiation factor 5 1.67083
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.65693
NGDN neuroguidin, EIF4E binding protein 1.60243
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.46099
RPS6 ribosomal protein S6 1.38294
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.32221
EEF2 eukaryotic translation elongation factor 2 1.1803
AGO1 argonaute RISC catalytic component 1 1.02929
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.981473
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.946382
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.938795
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.871806
GCDH glutaryl-CoA dehydrogenase 0.85388
ATF4 activating transcription factor 4 0.818075
USP24 ubiquitin specific peptidase 24 0.801104
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.797895
INS insulin 0.775014
EEF2K eukaryotic elongation factor 2 kinase 0.770451
BZW2 basic leucine zipper and W2 domains 2 0.766804
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.759069
CSN1S1 casein alpha s1 0.681591
MRI1 methylthioribose-1-phosphate isomerase 1 0.658619
EIF5B eukaryotic translation initiation factor 5B 0.657326
RALY RALY heterogeneous nuclear ribonucleoprotein 0.624355
FIGLA folliculogenesis specific basic helix-loop-helix 0.620104
TRMT61A tRNA methyltransferase 61A 0.609932
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.572162
NOBOX NOBOX oogenesis homeobox 0.54771
DAOA D-amino acid oxidase activator 0.498636
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.451631
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.442896
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.41612
ELF2 E74-like factor 2 (ets domain transcription factor) 0.41612
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.401693
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.397035
GRM3 glutamate receptor, metabotropic 3 0.392001
PDIA4 protein disulfide isomerase family A, member 4 0.387365
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 0.382739
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.381969
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.381584
EIF4A1 eukaryotic translation initiation factor 4A1 0.377738
RGS2 regulator of G-protein signaling 2 0.371599
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.362804
GSK3B glycogen synthase kinase 3 beta 0.357086
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 0.356324
EIF3F eukaryotic translation initiation factor 3, subunit F 0.351382
FOXO3 forkhead box O3 0.351382
DPYSL2 dihydropyrimidinase-like 2 0.344178
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.323825
PDLIM5 PDZ and LIM domain 5 0.323075
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.315586
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.315586
RGS4 regulator of G-protein signaling 4 0.307749
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.295489
EIF4B eukaryotic translation initiation factor 4B 0.294748
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.292897
IGF1 insulin-like growth factor 1 (somatomedin C) 0.290678
XPOT exportin, tRNA 0.290308
ASPA aspartoacylase 0.270068
IPO13 importin 13 0.262025
NRF1 nuclear respiratory factor 1 0.258745
PDIA6 protein disulfide isomerase family A, member 6 0.255834
PFKM phosphofructokinase, muscle 0.248216
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.24713
RPS17 ribosomal protein S17 0.234533
IL1RN interleukin 1 receptor antagonist 0.229888
DRD3 dopamine receptor D3 0.218563
NRG1 neuregulin 1 0.218212
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.217511
DTNBP1 dystrobrevin binding protein 1 0.198991
NCK1 NCK adaptor protein 1 0.198991
XPO5 exportin 5 0.194371
BMP15 bone morphogenetic protein 15 0.19307
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.177724
HIP1R huntingtin interacting protein 1 related 0.169604
TFG TRK-fused gene 0.168598
PER3 period circadian clock 3 0.167366