eukaryotic translation initiation factor 2 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA. (Gene Ontology, GO_0005850)
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Genes

117 proteins co-occuring with the eukaryotic translation initiation factor 2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 3.56405
EIF5 eukaryotic translation initiation factor 5 2.87736
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.77527
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2.47256
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 2.05612
EIF4B eukaryotic translation initiation factor 4B 2.04885
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 1.89316
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.69154
ATF4 activating transcription factor 4 1.63956
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.63301
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.62236
EIF5B eukaryotic translation initiation factor 5B 1.62236
EIF4E eukaryotic translation initiation factor 4E 1.5943
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.54235
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.46043
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 1.42711
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 1.40019
EIF3C eukaryotic translation initiation factor 3, subunit C 1.37575
NGDN neuroguidin, EIF4E binding protein 1.25075
EEF2 eukaryotic translation elongation factor 2 1.23818
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.2179
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.2086
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.15672
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.15109
CSN1S1 casein alpha s1 1.14904
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.13574
GCDH glutaryl-CoA dehydrogenase 1.12143
AGO1 argonaute RISC catalytic component 1 1.03929
EIF5A eukaryotic translation initiation factor 5A 1.03479
DTD1 D-tyrosyl-tRNA deacylase 1 0.984393
BZW2 basic leucine zipper and W2 domains 2 0.96792
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.956874
CDC123 cell division cycle 123 0.94876
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.886551
RPS6 ribosomal protein S6 0.883782
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.880094
ATF6 activating transcription factor 6 0.862609
CELF1 CUGBP, Elav-like family member 1 0.840564
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.834138
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.815322
DDIT3 DNA-damage-inducible transcript 3 0.809359
XBP1 X-box binding protein 1 0.759524
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.753623
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.750904
DCD dermcidin 0.707924
ERN1 endoplasmic reticulum to nucleus signaling 1 0.695148
LGTN ligatin 0.662072
ELF2 E74-like factor 2 (ets domain transcription factor) 0.625206
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.598538
CPNE6 copine VI (neuronal) 0.587199
NCK1 NCK adaptor protein 1 0.563017
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.540294
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 0.534951
ATF5 activating transcription factor 5 0.49742
TXNL4B thioredoxin-like 4B 0.4958
ATF3 activating transcription factor 3 0.486904
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.486096
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.485693
INS insulin 0.460401
ATL2 atlastin GTPase 2 0.458803
TRMT61A tRNA methyltransferase 61A 0.444482
NRF1 nuclear respiratory factor 1 0.430647
RALY RALY heterogeneous nuclear ribonucleoprotein 0.427497
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.41221
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.402859
BAG5 BCL2-associated athanogene 5 0.397423
EEF2K eukaryotic elongation factor 2 kinase 0.39626
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.387365
EEF1B2 eukaryotic translation elongation factor 1 beta 2 0.368153
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.367006
MTIF2 mitochondrial translational initiation factor 2 0.362422
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.359371
DENR density-regulated protein 0.355183
PYGB phosphorylase, glycogen; brain 0.352522
PYGL phosphorylase, glycogen, liver 0.352142
PYGM phosphorylase, glycogen, muscle 0.350243
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.338884
RPS5 ribosomal protein S5 0.337373
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.333979
USP9Y ubiquitin specific peptidase 9, Y-linked 0.313344
RNASEH2A ribonuclease H2, subunit A 0.302168
BCAP29 B-cell receptor-associated protein 29 0.291047
SPDEF SAM pointed domain containing ETS transcription factor 0.290308
CSDE1 cold shock domain containing E1, RNA-binding 0.277406
BAG3 BCL2-associated athanogene 3 0.276304
SSB Sjogren syndrome antigen B (autoantigen La) 0.257652
HARS histidyl-tRNA synthetase 0.257652
HSPA4 heat shock 70kDa protein 4 0.255834
MAPK1 mitogen-activated protein kinase 1 0.250751
EIF4H eukaryotic translation initiation factor 4H 0.249302
CSN2 casein beta 0.243879
OPN3 opsin 3 0.240636
EMC10 ER membrane protein complex subunit 10 0.239557
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.238837
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.238478
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.235249
CNGB3 cyclic nucleotide gated channel beta 3 0.234174
EIF4A1 eukaryotic translation initiation factor 4A1 0.227752
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.219969
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.210894
UBE2B ubiquitin-conjugating enzyme E2B 0.208137
EIF3G eukaryotic translation initiation factor 3, subunit G 0.20574
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.201672
EIF3E eukaryotic translation initiation factor 3, subunit E 0.190814
IPO5 importin 5 0.189222
ACLY ATP citrate lyase 0.181524
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.179167
CNGA3 cyclic nucleotide gated channel alpha 3 0.177154
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.170371
RIPK4 receptor-interacting serine-threonine kinase 4 0.170371
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.16477
TSFM Ts translation elongation factor, mitochondrial 0.162546
PEX10 peroxisomal biogenesis factor 10 0.161693
LARS leucyl-tRNA synthetase 0.161068
IFNA2 interferon, alpha 2 0.160254
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.159074
XPOT exportin, tRNA 0.158315