eucatropine-3416 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the eucatropine-3416 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACVR1B activin A receptor, type IB
ADM adrenomedullin
AJAP1 adherens junctions associated protein 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOD apolipoprotein D
APOM apolipoprotein M
ARHGAP4 Rho GTPase activating protein 4
ARID1A AT rich interactive domain 1A (SWI-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPN asporin
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BTBD7 BTB (POZ) domain containing 7
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CARF calcium responsive transcription factor
CASP5 caspase 5, apoptosis-related cysteine peptidase
CFLAR CASP8 and FADD-like apoptosis regulator
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL9A3 collagen, type IX, alpha 3
CTAGE5 CTAGE family, member 5
DIEXF digestive organ expansion factor homolog (zebrafish)
DPF1 D4, zinc and double PHD fingers family 1
E2F4 E2F transcription factor 4, p107/p130-binding
ELSPBP1 epididymal sperm binding protein 1
FADS3 fatty acid desaturase 3
FSCN1 fascin actin-bundling protein 1
FSTL1 follistatin-like 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
HDAC11 histone deacetylase 11
HEG1 heart development protein with EGF-like domains 1
HIST1H4F histone cluster 1, H4f
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KIAA0754 KIAA0754
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL24 kelch-like family member 24
LAMA2 laminin, alpha 2
LDLR low density lipoprotein receptor
LPAR4 lysophosphatidic acid receptor 4
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAOB monoamine oxidase B
MTMR8 myotubularin related protein 8
MTSS1L metastasis suppressor 1-like
MUC1 mucin 1, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGLY1 N-glycanase 1
NKX3-2 NK3 homeobox 2
NMT2 N-myristoyltransferase 2
NRSN2 neurensin 2
OASL 2'-5'-oligoadenylate synthetase-like
PARD3 par-3 family cell polarity regulator
PCDHGA10 protocadherin gamma subfamily A, 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCH1 phospholipase C, eta 1
POLL polymerase (DNA directed), lambda
POU4F1 POU class 4 homeobox 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RABGAP1 RAB GTPase activating protein 1
RGS12 regulator of G-protein signaling 12
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A8 S100 calcium binding protein A8
SDC2 syndecan 2
SDC3 syndecan 3
SH3BP2 SH3-domain binding protein 2
SLIT2 slit homolog 2 (Drosophila)
SMTN smoothelin
SNCG synuclein, gamma (breast cancer-specific protein 1)
SRPX sushi-repeat containing protein, X-linked
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TACR1 tachykinin receptor 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBX19 T-box 19
TK2 thymidine kinase 2, mitochondrial
TLE2 transducin-like enhancer of split 2
TMEM45A transmembrane protein 45A
TRIM36 tripartite motif containing 36
TTLL5 tubulin tyrosine ligase-like family member 5
UBE3A ubiquitin protein ligase E3A
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTRN utrophin
VASH2 vasohibin 2
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZCCHC4 zinc finger, CCHC domain containing 4
ZFHX4 zinc finger homeobox 4
ZIC3 Zic family member 3
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADIRF adipogenesis regulatory factor
ADRA2C adrenoceptor alpha 2C
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC7 armadillo repeat containing 7
ATF3 activating transcription factor 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C16ORF59 chromosome 16 open reading frame 59
CASP3 caspase 3, apoptosis-related cysteine peptidase
CENPQ centromere protein Q
CEP97 centrosomal protein 97kDa
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CLEC16A C-type lectin domain family 16, member A
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CORO2A coronin, actin binding protein, 2A
CRLF1 cytokine receptor-like factor 1
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FAM86C1 family with sequence similarity 86, member C1
FCHSD2 FCH and double SH3 domains 2
FKBP14 FK506 binding protein 14, 22 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
GPR87 G protein-coupled receptor 87
GPX2 glutathione peroxidase 2
HIRA histone cell cycle regulator
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
KLHL26 kelch-like family member 26
KRT86 keratin 86, type II
LIN37 lin-37 DREAM MuvB core complex component
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEH1 melanoma antigen family H1
MATK megakaryocyte-associated tyrosine kinase
MTCL1 microtubule crosslinking factor 1
MTMR12 myotubularin related protein 12
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PGP phosphoglycolate phosphatase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POR P450 (cytochrome) oxidoreductase
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PQLC1 PQ loop repeat containing 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RFTN1 raftlin, lipid raft linker 1
RIN2 Ras and Rab interactor 2
RNF126 ring finger protein 126
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRAGB Ras-related GTP binding B
SIRT6 sirtuin 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC46A3 solute carrier family 46, member 3
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX5 syntaxin 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARP TCR gamma alternate reading frame protein
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM2 transmembrane protein 2
TNS2 tensin 2
TPST1 tyrosylprotein sulfotransferase 1
TRAIP TRAF interacting protein
TRIM66 tripartite motif containing 66
TTBK2 tau tubulin kinase 2
TTC30A tetratricopeptide repeat domain 30A
TUBGCP5 tubulin, gamma complex associated protein 5
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMYM3 zinc finger, MYM-type 3
ZNF165 zinc finger protein 165
ZNF219 zinc finger protein 219