etynodiol-6678 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the etynodiol-6678 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM22 ADAM metallopeptidase domain 22
AKR1C2 aldo-keto reductase family 1, member C2
ANGEL2 angel homolog 2 (Drosophila)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF53 chromosome 17 open reading frame 53
C1QL1 complement component 1, q subcomponent-like 1
CEP295 centrosomal protein 295kDa
CERS4 ceramide synthase 4
CFLAR CASP8 and FADD-like apoptosis regulator
CLTCL1 clathrin, heavy chain-like 1
CNR2 cannabinoid receptor 2 (macrophage)
COBL cordon-bleu WH2 repeat protein
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTNA dystrobrevin, alpha
DUSP2 dual specificity phosphatase 2
EPHA5 EPH receptor A5
EPHB2 EPH receptor B2
EPS8L1 EPS8-like 1
ETV1 ets variant 1
ETV7 ets variant 7
FAM63A family with sequence similarity 63, member A
FCAR Fc fragment of IgA receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLJ42627 uncharacterized LOC645644
GBP2 guanylate binding protein 2, interferon-inducible
GOLGA8A golgin A8 family, member A
GREB1L growth regulation by estrogen in breast cancer-like
GSN gelsolin
H2AFX H2A histone family, member X
HEMK1 HemK methyltransferase family member 1
HFE hemochromatosis
HKDC1 hexokinase domain containing 1
HRASLS2 HRAS-like suppressor 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IDS iduronate 2-sulfatase
ING4 inhibitor of growth family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK3 Janus kinase 3
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
KRT85 keratin 85, type II
LMO2 LIM domain only 2 (rhombotin-like 1)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRN3 leucine rich repeat neuronal 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MATK megakaryocyte-associated tyrosine kinase
MTCP1 mature T-cell proliferation 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCAM1 neural cell adhesion molecule 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NOX1 NADPH oxidase 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGFR opioid growth factor receptor
PCDHA9 protocadherin alpha 9
PDE5A phosphodiesterase 5A, cGMP-specific
PGP phosphoglycolate phosphatase
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PKNOX2 PBX/knotted 1 homeobox 2
PRDM2 PR domain containing 2, with ZNF domain
PRMT2 protein arginine methyltransferase 2
PRR5 proline rich 5 (renal)
PTPRF protein tyrosine phosphatase, receptor type, F
PVR poliovirus receptor
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNX13 sorting nexin 13
TGFB1 transforming growth factor, beta 1
TLN2 talin 2
TNPO2 transportin 2
TYMP thymidine phosphorylase
WSB1 WD repeat and SOCS box containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM23 ADAM metallopeptidase domain 23
ALPK1 alpha-kinase 1
ATAD5 ATPase family, AAA domain containing 5
BMP15 bone morphogenetic protein 15
C14ORF105 chromosome 14 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD101 CD101 molecule
CD70 CD70 molecule
CDH7 cadherin 7, type 2
CFAP69 cilia and flagella associated protein 69
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPED1 cadherin-like and PC-esterase domain containing 1
CST1 cystatin SN
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDN dendrin
DNAH17 dynein, axonemal, heavy chain 17
DSPP dentin sialophosphoprotein
FGF23 fibroblast growth factor 23
FOXN2 forkhead box N2
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GPR19 G protein-coupled receptor 19
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
HAMP hepcidin antimicrobial peptide
HIST1H2AJ histone cluster 1, H2aj
HIST1H3A histone cluster 1, H3a
IFNA14 interferon, alpha 14
IL36RN interleukin 36 receptor antagonist
IL7 interleukin 7
IREB2 iron-responsive element binding protein 2
ITGB7 integrin, beta 7
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
KLK7 kallikrein-related peptidase 7
LY6D lymphocyte antigen 6 complex, locus D
MAGEH1 melanoma antigen family H1
MFGE8 milk fat globule-EGF factor 8 protein
MFSD11 major facilitator superfamily domain containing 11
MGP matrix Gla protein
MILR1 mast cell immunoglobulin-like receptor 1
MRAS muscle RAS oncogene homolog
MTERF4 mitochondrial transcription termination factor 4
MTSS1L metastasis suppressor 1-like
MXRA8 matrix-remodelling associated 8
MYBBP1A MYB binding protein (P160) 1a
NBEAL2 neurobeachin-like 2
NLGN1 neuroligin 1
NME5 NME/NM23 family member 5
NPIPB15 nuclear pore complex interacting protein family, member B15
ODF2 outer dense fiber of sperm tails 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PICK1 protein interacting with PRKCA 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PROL1 proline rich, lacrimal 1
PROX1 prospero homeobox 1
RAB40A RAB40A, member RAS oncogene family
RNF39 ring finger protein 39
RPH3A rabphilin 3A
SAMD9 sterile alpha motif domain containing 9
SCEL sciellin
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRT6 sirtuin 6
SIX3 SIX homeobox 3
SLC16A6 solute carrier family 16, member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAGLN transgelin
TEAD3 TEA domain family member 3
TENM1 teneurin transmembrane protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBI transforming growth factor, beta-induced, 68kDa
TM6SF1 transmembrane 6 superfamily member 1
TMEM140 transmembrane protein 140
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
USB1 U6 snRNA biogenesis 1
ZNF480 zinc finger protein 480
ZNF528 zinc finger protein 528